Results 211 to 220 of about 232,812 (303)

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Long-term clinical outcomes from the smart start trial: rituximab, lenalidomide and ibrutinib in patients with newly diagnosed large B-cell lymphoma

Blood Cancer Journal
Karan L. Chohan, Eduardo Edelman Saul, R. Eric Davis, Fredrick Hagemeister, Raphael Steiner, Luis Fayad, Sairah Ahmed, Alma Rodriguez, Swaminathan P. Iyer, Ranjit Nair, Francisco Vega, Dai Chihara, Paolo Strati, Preetesh Jain, Luis Malpica Castillo, Chijioke Nze, Fateeha Furqan, Ayushi Chauhan, Mark P. Hamilton, Jared Henderson, Anath C. Lionel, Christopher R. Flowers, Sattva Neelapu, Michael R. Green, Jason Westin   +24 more
doaj   +1 more source

Synchronous Coexistence of JAK2 V617F-Positive Essential Thrombocythemia and IgG Kappa Multiple Myeloma in an Octogenarian Patient: A Case Report. [PDF]

Case Rep Med
Ribero-Vargas M, Ahumada-Córdoba F, Silva-Pérez NM, Ribero-Vargas D.   +3 more
europepmc   +1 more source

A prospective, phase IV study of ixazomib, pomalidomide and dexamethasone in patients with relapsed or refractory multiple myeloma

British Journal of Haematology, EarlyView.
Runfeng Zhang, Hong Yu, Miao Chen, Xiaoqi Qin, Jie Xiao, Yun Leng, Mingzhe Zhao, Jie Yu, Chunjie Qin, Xiuju Wang, Jingcheng Zhang, Wei Wang, Wenming Chen, Yanping Ma, Rong Fu, Junling Zhuang   +15 more
wiley   +1 more source

Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review

British Journal of Pharmacology, EarlyView.
Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß, Paul Goerke, Malte Kelm, Amin Polzin   +3 more
wiley   +1 more source

Narrative nursing for prolonged myelosuppression after autologous stem cell transplantation in multiple myeloma: A case report. [PDF]

Medicine (Baltimore)
Huang Q, Jiang M.
europepmc   +1 more source

Leveraging venetoclax‐induced autophagy to enhance AUTAC‐mediated Mcl1 degradation and overcome resistance in acute myeloid leukaemia

British Journal of Haematology, EarlyView.
Ahmed M. Elshazly, Nayyerehalsadat Hosseini, Janakiram R. Vangala, Xiaoyan Hu, Steven Grant, Senthil K. Radhakrishnan   +5 more
wiley   +1 more source

MCL‐1 inhibition triggers a largely reversible cardiac stress signature in a humanised mouse model

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Myeloid cell leukaemia‐1 (MCL‐1) is an essential anti‐apoptotic protein and a promising therapeutic target in oncology. Early clinical studies of MCL‐1 inhibitors reported unexpected elevations in cardiac troponin, raising concerns about potential cardiotoxicity.
Markus B. Heckmann, Zsanett Papdi, Nils J. Strauch, Daniel Finke, Marc‐Steffen Raab, Antje Blank, Norbert Frey, Lorenz H. Lehmann   +7 more
wiley   +1 more source

Plasmacytomas in Extramedullary Manifestation of Multiple Myeloma: A Case Report. [PDF]

Clin Med Insights Case Rep
Hmayed J, Fadel D, Albayeh A, Jreij C, Karam K, El Sett L, Fares C.   +6 more
europepmc   +1 more source

From infusion to pills in acute myeloid leukaemia: Reorganizing care beyond the infusion unit

British Journal of Haematology, EarlyView.
Fortunato Morabito, Enrica Antonia Martino, Antonella Bruzzese, Nicola Amodio, Santino Caserta, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Ernesto Vigna, Massimo Gentile   +11 more
wiley   +1 more source