Results 81 to 90 of about 232,812 (303)
Experimental Hematology & Oncology, 2017 B cell lymphoma and multiple myeloma (MM) are the most common hematological malignancies which benefit from therapeutic monoclonal antibodies (mAbs)-based immunotherapies.
Li Zhang +4 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló +5 more
wiley +1 more source
Frontiers in ImmunologyAutologous stem cell transplantation (ASCT) and chimeric antigen receptor T-cells (CAR-T) have been used as consolidation therapies for patients with refractory/relapsed B cell non-Hodgkin’s lymphoma (R/R B-NHL) in remission after second-line ...
Danyang Li +15 more
doaj +1 more source
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source
Widespread intronic polyadenylation diversifies immune cell transcriptomes
Nature Communications, 2018 Recognition of intronic polyadenylation (IpA) signals can lead to expression of truncated proteins lacking C terminal domains. Analysis of 3ʹ -seq and RNA-seq shows that IpA is widespread in circulating immune cells, while multiple myeloma cells show ...
Irtisha Singh +8 more
doaj +1 more source
Autológ őssejtátültetés szerepe a myeloma multiplex kezelésében
, 2013 Autológ őssejtátültetés szerepe a myeloma multiplex kezelésében Tamáska Péter (DEOEC – ÁOK, VI évfolyam 6. csoport) Összefoglalás: A myeloma multiplex a csontvelő multifokális, monoklonális, rosszindulatú plazmasejtes daganata.
Tamáska, Péter
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Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma
BMC Cancer, 2018 Background Multiple myeloma (MM) patients with t(14;20) have a poor prognosis and their outcome has not improved following the introduction of bortezomib (Bzb).
Ya-Wei Qiang +8 more
doaj +1 more source
Myelomatous Pleural Effusion [PDF]
Multiple myeloma (MM) is a common hematologic malignancy. Pleural effusion is a rare presenting feature of multiple myeloma which carries a poor prognosis.
غیاثی, تقی +3 more
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