Results 101 to 110 of about 232,812 (303)

P860: THE DE NOVO DNA METHYLTRANSFERASE DNMT3B PLAYS AN IMPORTANT ROLE IN MM CELL GROWTH, CLONOGENICITY AND DRUG RESPONSE

open access: yesHemaSphere, 2022
C. Muylaert   +7 more
doaj   +1 more source

Outcomes in patients with refractory/relapsed CNS lymphoma treated in complete remission: autologous transplantation vs. CAR-T therapy

open access: yesCancer Immunology, Immunotherapy
Background Autologous hematopoietic cell transplantation (ASCT) is a reasonable consolidation therapy for eligible patients with chemosensitive relapsed central nervous system lymphoma (CNSL) who have achieved complete remission (CR) and maintained the ...
Fan Yang   +10 more
doaj   +1 more source

New Treatment Approaches Multiple Myeloma

open access: yes, 2018
The thesis is on current treatment approach to multiple Myeloma.Though an incurable disease as of now, great leaps have been taken in Myeloma management. This thesis focuses on different treatmet regimens used to treat different class of myeloma patients:
Issack, Sadam Mohamed
core  

Artificial intelligence to assist better myeloma care, is it the time?

open access: yes, 2019
Myeloma treatment made an enormous progress during the last decade. Armamentarium is grossly enlarging each year in the field of treatment. Parallel to the progress achieved to provide better care for myeloma patients, machine learning processes via ...
Sevindik, Ömür Gökmen
core   +1 more source

The Myeloma Globulins [PDF]

open access: yesBritish Journal of Cancer, 1960
P, HOUGHTON, N H, MARTIN
openaire   +2 more sources

From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
wiley   +1 more source

Daratumumab kezeléssel szerzett tapasztalataink myeloma multiplexben

open access: yes
Munkámban a myeloma multiplex betegség leírásával és annak kezelésével foglalkoztam. Kitértem a betegség általános jellemzőire és kezelési módjaira. Mivel azonban a hematológia folyamatosan fejlődik, ezért a myeloma multiplex kezelésében is jelentek meg
Varga, Lilla
core  

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Multiple myeloma in young ages

open access: yes, 2017
A myeloma multiplex a malignus hematológiai betegségek kb. 10%-át teszi ki. Alapvetően az idősebb populációt érinti, diagnóziskor a betegek átlagéletkora 69 év. Ettől eltérően azonban, jóval fiatalabb életkorban is megjelenhet.
Pásztor, Janka
core  

Automated B‐cell and plasma cell identification using unsupervised clustering by FlowSOM and an excel‐based classification model

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Manual gating for plasma cell (PC) identification in multiparametric flow cytometry (MFC) is time‐consuming and operator‐dependent, especially when PCs are scarce. Artificial intelligence approaches such as unsupervised clustering (e.g., FlowSOM) map high‐dimensional data that still require expert interpretation.
Ethan James Gantana   +3 more
wiley   +1 more source

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