Results 101 to 110 of about 232,812 (303)
Background Autologous hematopoietic cell transplantation (ASCT) is a reasonable consolidation therapy for eligible patients with chemosensitive relapsed central nervous system lymphoma (CNSL) who have achieved complete remission (CR) and maintained the ...
Fan Yang +10 more
doaj +1 more source
New Treatment Approaches Multiple Myeloma
The thesis is on current treatment approach to multiple Myeloma.Though an incurable disease as of now, great leaps have been taken in Myeloma management. This thesis focuses on different treatmet regimens used to treat different class of myeloma patients:
Issack, Sadam Mohamed
core
Artificial intelligence to assist better myeloma care, is it the time?
Myeloma treatment made an enormous progress during the last decade. Armamentarium is grossly enlarging each year in the field of treatment. Parallel to the progress achieved to provide better care for myeloma patients, machine learning processes via ...
Sevindik, Ömür Gökmen
core +1 more source
From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs
New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
wiley +1 more source
Daratumumab kezeléssel szerzett tapasztalataink myeloma multiplexben
Munkámban a myeloma multiplex betegség leírásával és annak kezelésével foglalkoztam. Kitértem a betegség általános jellemzőire és kezelési módjaira. Mivel azonban a hematológia folyamatosan fejlődik, ezért a myeloma multiplex kezelésében is jelentek meg
Varga, Lilla
core
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley +1 more source
Multiple myeloma in young ages
A myeloma multiplex a malignus hematológiai betegségek kb. 10%-át teszi ki. Alapvetően az idősebb populációt érinti, diagnóziskor a betegek átlagéletkora 69 év. Ettől eltérően azonban, jóval fiatalabb életkorban is megjelenhet.
Pásztor, Janka
core
Abstract Manual gating for plasma cell (PC) identification in multiparametric flow cytometry (MFC) is time‐consuming and operator‐dependent, especially when PCs are scarce. Artificial intelligence approaches such as unsupervised clustering (e.g., FlowSOM) map high‐dimensional data that still require expert interpretation.
Ethan James Gantana +3 more
wiley +1 more source

