Results 111 to 120 of about 232,812 (303)
Immune microenvironment and its influence on CAR-T treatment outcomes in B-NHL
Discover OncologyB-cell non-Hodgkin’s lymphoma (B-NHL) is a highly heterogeneous tumor. Currently, CAR-T cells have been widely used in the treatment of B-cell lymphomas, with a complete response rate reaching 40%-60%.Danyang Li, Zhonghua Fu, Rui Liu, Fan Yang, Ting Zhang, Lixia Ma, Yuelu Guo, Miaomiao Cao, Biping Deng, Alex H. Chang, Xiaoyan Ke, Kai Hu +11 moredoaj +1 more sourceDental respects of myeloma multiplex
, 2018 Multiple myeloma (MM) is a blood dyscrasia associated with malignant plasma cells, producing monoclonal immunoglobulins (Igs). Oral manifestation associated with multiple myeloma is often overlooked as pathological Igs invade multiple organs giving rise ...Upreti, Bhumikacore Circulating tumor plasma cells quantification in newly diagnosed transplant ineligible real world multiple myeloma patients: Comparison of single‐platform flow cytometry versus next generation flow
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract
Circulating tumor plasma cells (CTCs) at diagnosis are independent prognostic markers in newly diagnosed multiple myeloma (NDMM). Flow cytometry (FC) enables sensitive and cost‐effective CTC quantification, but prognostic cut‐offs vary across studies.Elona Saraci, Alessandra Larocca, Roberto Ria, Silvia Mangiacavalli, Giulia Benevolo, Nicola Giuliani, Renato Zambello, Angelo Belotti, Ilaria Rizzello, Antonietta Pia Falcone, Iolanda Donatella Vincelli, Mariagrazia Michieli, Sonia Ronconi, Patrizia Tosi, Maria letizia Mosca Siez, Alessandro Allegra, Maide Maria Cavalli, Matilde Scaldaferri, Ilaria Fedele, Marco Burdisso, Tania Villanova, Cristina Velluti, Marcello Capriata, Donato Mannina, Anna Maria Cafro, Elisabetta Antonioli, Sonia Morè, Mario Boccadoro, Benedetto Bruno, Sara Bringhen, Mattia D'Agostino +30 morewiley +1 more sourceEvaluation of a multiple myeloma synthetic cell mimic as an assay control for flow cytometry
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract
The reliability of clinical flow cytometry assays hinges on the availability of robust assay controls that accurately reflect representative samples. Widely used conventional assay controls, such as cell lines, often fail to replicate the phenotypical and biophysical properties of representative primary samples resulting in gating variability ...Dhong Hyun Lee, Mike Liu, Kanwal Palla, Subhanip Biswas, Swetha Pratyusha Gunturu, Brian Kerfs, Kristine Valenteros, Sarah Kotanchiyev, Shari Kaiser, Justine Dell'Aringa +9 morewiley +1 more sourceP1195: A PROSPECTIVE STUDY OF TARGETED SEQUENTIAL IMMUNOTHERAPY. IN PATIENTS WITH RELAPSED REFRACTORY PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA.
HemaSphere, 2023 Yuelu Guo, Kai Hu, Xiaoyan Ke, Teng Xu, Shaomei Feng, Peihao Zheng, Lixia MA, Fan Yang, Hui Shi, Biping Deng, Liu Rui, Zhonghua Fu +11 moredoaj +1 more sourceEpigenetic regulation of CD38/CD48 by KDM6A mediates NK cell response in multiple myeloma
Nature CommunicationsAnti-CD38 monoclonal antibodies like Daratumumab (Dara) are effective in multiple myeloma (MM); however, drug resistance ultimately occurs and the mechanisms behind this are poorly understood.Jiye Liu, Lijie Xing, Jiang Li, Kenneth Wen, Ning Liu, Yuntong Liu, Gongwei Wu, Su Wang, Daisuke Ogiya, Tian-Yu Song, Keiji Kurata, Johany Penailillo, Eugenio Morelli, Tingjian Wang, Xiaoning Hong, Annamaria Gulla, Yu-Tzu Tai, Nikhil Munshi, Paul Richardson, Ruben Carrasco, Teru Hideshima, Kenneth C. Anderson +21 moredoaj +1 more sourcePrevalence of transthyretin cardiac amyloidosis in undifferentiated heart failure with preserved ejection fraction
ESC Heart Failure, Volume 12, Issue 2, Page 1176-1182, April 2025.Abstract Aims
Transthyretin amyloid cardiomyopathy (ATTR‐CM) is an increasinglyrecognized cause of heart failure with preserved ejection fraction (HFpEF), which may be diagnosed non‐invasively using 99mTc 3,3‐diphosphono‐1,2‐propanodicarboxylic acid (DPD) scintigraphy‐based diagnostic criteria.L. Healy, G. Giblin, A. Gray, N. Starr, L. Murphy, D. O'Sullivan, E. Kavanagh, C. Howley, C. Tracey, E. Morrin, A. McDaid, A. Clarke, J.O. O'Neill, E. Joyce, M. O'Connell, N. G. Mahon +15 morewiley +1 more sourceComprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes. [PDF]
Multiple myeloma is a treatable, but currently incurable, hematological malignancy of plasma cells characterized by diverse and complex tumor genetics for which precision medicine approaches to treatment are lacking.Cho, Hearn Jay, Jewell, Scott, DeRome, Mary, Donnelly, Andrea, Christofferson, Austin W., Aldrich, Jessica, Nasser, Sara, Boateng, Martin, Carpten, John, Rohrer, Daniel, Cho, Hearn, Orloff, Gregory, Cuyugan, Lori, Auclair, Daniel, Livermore, Brianne, McBride, Kyle, Jakubowiak, Andrzej, Helland, Adrienne, Reiman, Rebecca, Stumph, Jennifer, Anderson, Kenneth, Wolf, Jeffrey, Jagannath, Sundar, Usmani, Saad Z., Turner, Bryce, Liang, Winnie, Berdeja, Jesus, Skerget, Sheri, Stephenson, Kristi, Kidd, Pam, Adkins, Jonathan R., Vij, Ravi, Miller, Chase, Keats, Jonathan J., Niesvizky, Ruben, Anderson, Kenneth C., Usmani, Saad, Adkins, Jonathan, Aldrich, Jessica L., Kyman, Shari, DAgostino, Mattia, Jakubowiak, Andrzej J., Keats, Jonathan, Chari, Ajai, Kirchhoff, Meghan, Liang, Winnie S., Benard, Brooks, Kurdoglu, Ahmet, Tassone, Erica, Berdeja, Jesús G., D’Agostino, Mattia, Christofferson, Austin, Yellapantula, Venkata, Collison, Kimberly, Zaugg, Barbara, Siegel, David S., Jewell, Scott D., Lonial, Sagar, Levy, Moshe, Gutierrez, Norma, Legendre, Christophe, Gamella, Manuela, Penaherrera, Daniel, Toone, Maureen, McDonald, Jackie, Siegel, David, Washington, Megan, Rohrer, Daniel C., Rogers, Jennifer, Gutiérrez, Norma Carmen, Blanski, Alex, Craig, David, Liles, Darla +72 morecore +1 more sourceLongitudinal Swallowing and Salivary Changes With CLR 131 and Re‐Irradiation in Recurrent Head and Neck Cancer
Head &Neck, EarlyView.ABSTRACT Background
Patients with recurrent head and neck cancer (HNC) often present with severe, persistent dysphagia and xerostomia following prior chemoradiation. Although swallowing impairments and salivary dysfunction have been reported in this population, prior longitudinal studies have not examined changes in salivary composition or how these ...Jenni Wu, Sara Gustafson, Meredith Hyun, Roxana Alexandridis, Mark Nicosia, Timothy McCulloch, Justine Bruce, Randall Kimple, Nicole Rogus‐Pulia +8 morewiley +1 more source
