A BALB/c Mouse IgA Myeloma Protein That Binds Salmonella Flagellar Protein [PDF]
, 1975 Alan Smith, M Potter
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Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, EarlyView.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
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The interaction between protein A and immunoglobulin G as studied with the Fc‐fragment of a myeloma protein by circular dichroism [PDF]
, 1975 Ingvar Sjöholm
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Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture
International Journal of Cancer, EarlyView.Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert +3 more
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Suppression of MOPC‐167 Growth In Vivo by Immunization against the Idiotype of the MOPC‐167 Myeloma Protein [PDF]
, 1979 Nobuo Sakato +2 more
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Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
International Journal of Cancer, EarlyView.Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
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Studies on the initiation of protein synthesis in mouse myeloma tumors [PDF]
, 1975 George H. Jones
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International Journal of Cancer, EarlyView.Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li +7 more
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Monovalent cations and the cut-off of host-cell protein synthesis in mouse myeloma cells infected with an alphavirus [PDF]
, 1979 K.P. Cusack
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CD86, the double agent: Significance of CD86 expression in B‐cell malignancies
International Journal of Cancer, EarlyView.Abstract Bypassing the anti‐tumor functions of the immune system is one of the keys to tumor survival. Tumors, especially hematological tumors, produce or express factors that retune T and B cells to inhibit the immune response. Coreceptors CD28 and CTLA‐4, and their ligands, CD80 and CD86, are involved in the immunological synapse and play an ...
Gábor Barna +4 more
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