Results 151 to 160 of about 76,403 (315)

Characterizing Cellular Expansion of Idecabtagene Vicleucel and Association with Clinical Efficacy and Safety in Patients with Triple‐Class‐Exposed Relapsed/Refractory Multiple Myeloma

The Journal of Clinical Pharmacology, EarlyView.
Abstract Idecabtagene vicleucel (ide‐cel, ABECMA) is an autologous, B‐cell maturation antigen‐directed, chimeric antigen receptor (CAR) T‐cell therapy, which has demonstrated significantly improved progression‐free survival (PFS) and overall response rate (ORR) in patients with triple‐class‐exposed relapsed/refractory multiple myeloma (TCE RRMM). Here,
Fan Wu, Xirong Zheng, Joseph Burnett, Madhan Masilamani, Wanying Zhang, Xiaobo Zhong, Andrea Caia, Mark Cook, Julia Piasecki, Anna Kondic, Manisha Lamba, Jian Zhou   +11 more
wiley   +1 more source

Causal insights into multiple myeloma: The impact of circulating inflammatory proteins and metabolites. [PDF]

Medicine (Baltimore)
Zhang P, Li H, Huang Y, Sha H.
europepmc   +1 more source

The role of artificial intelligence in pharmacy: Revolutionizing drug development and beyond

Journal of Intelligent Medicine, EarlyView.
This comprehensive review explores the integration of artificial intelligence (AI) in the field of pharmacy, covering advancements in drug discovery, personalized medicine, medication management, and patient care. It synthesizes current research, methodologies, and future prospects, offering insights into how AI technologies are reshaping ...
Usman Shettima Usman, Farogh Ahsan, Muhammad Alanjiro, Saidu Yahaya Bataba, Jibrin Abdullahi Dallatu, Tarique Mahmood, Shahzadi Bano, Jamal Akhtar Ansari, Saba Parveen   +8 more
wiley   +1 more source

Sensitive inhibitory effect of interferon-alpha on M-protein secretion of human myeloma cells [PDF]

, 1989
H Tanaka, O Tanabe, K Iwato, Hideki Asaoku, Hideaki Ishikawa, M Nobuyoshi, Masanori Kawano, Atsushi Kuramoto   +7 more
openalex   +1 more source

Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond

Macromolecular Bioscience, EarlyView.
Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley   +1 more source

Integrative analysis of bulk and single-cell gene expression profiles to identify bone marrow mesenchymal cell heterogeneity and prognostic significance in multiple myeloma. [PDF]

J Transl Med
Ju FE, Huang BH, Wu H, Zou B, Chen SN, Sang XY, Liang WY, Liu ZX, Zhang ZX, Yang ZY, Liang YT, Liang YL, Liu H, Dong ZX, Liu XQ, Zheng LY, Zeng JC, Wang JH, Qi L, Zhang XD, Zheng Y, Li J.   +21 more
europepmc   +1 more source

The circular dichroism of phosphocholine-specific mouse hybridoma and myeloma proteins: Unusual properties of the hybridoma protein 101.6g6 [PDF]

, 1985
N. Martin Young, Ross E. Williams, J L Claflin   +2 more
openalex   +1 more source

The Dual Role of Exosomes in the Tumor Microenvironment: From Pro‐Tumorigenic Signaling to Immune Modulation

Med Research, EarlyView.
Tumor‐derived exosomes influence proliferation, invasion, angiogenesis, metabolic adaptation, and resistance to therapy. They also shape the immune landscape by modulating antigen presentation, suppressing cytotoxic lymphocyte activity, and promoting the expansion of immunosuppressive cell populations. Although frequently associated with immune evasion,
Jiale Li, Jun Peng, Jiachong Wang, Zigui Chen   +3 more
wiley   +1 more source

Transcriptional analysis of BMP2 and BMP6 in patients with newly diagnosed multiple myeloma. [PDF]

Oncol Lett
Stoikos P, Giannakoulas A, Kouvata E, Stefani G, Vassilopoulos G, Giannakoulas N.   +5 more
europepmc   +1 more source

Idiotype-anti-idiotype regulation. I. Immunization with a levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the activation of silent clones. [PDF]

, 1981
Constantin A. Bona, Ellen Heber‐Katz, W E Paul   +2 more
openalex   +1 more source