Results 161 to 170 of about 76,403 (315)

The Hsp90β Isoform: An Attractive Target for Drug Development

Medicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury, Terin D'Amico, Brian S. J. Blagg   +2 more
wiley   +1 more source

DEK facilitates bortezomib resistance of multiple myeloma by modulating ferroptosis. [PDF]

Clin Exp Med
Wang H, Zhang J, Chen L, Ren H, Liu C, Wu HK, Qiu H, Lu J, Zhou L.   +8 more
europepmc   +1 more source

Thymine and guanine base specificity of human myeloma proteins with anti-DNA activity. [PDF]

, 1986
Moncef Zouali, B. David Stollar
openalex   +1 more source

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

Medicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar, Tobias Werner, Mihajlo Gajic, Holger Stark, Bassem Sadek   +4 more
wiley   +1 more source

Utilizing genomics to identify novel immunotherapeutic targets in multiple myeloma high-risk subgroups. [PDF]

Genome Med
Liu E, Jaouadi O, Sharma R, Becker N, Johnson TS, Sudha P, Chopra VS, Zafar F, Hamidi H, Pawlyn C, Suvannasankha A, Abonour R, Walker BA.   +12 more
europepmc   +1 more source

Plasma cell labeling index and beta 2-microglobulin predict survival independent of thymidine kinase and C-reactive protein in multiple myeloma [see comments] [PDF]

, 1993
PR Greipp, JA Lust, O'Fallon Wm, JA Katzmann, TE Witzig, RA Kyle   +5 more
openalex   +1 more source

A geriatrician's approach to managing the complex older adult with obesity

Obesity, EarlyView.
Abstract The prevalence of obesity in older adults is rapidly increasing due to the demographic shift occurring globally. Older adults with obesity face health care challenges due to multimorbidity, functional dependency, and disability. This population often has prior history of struggles through weight‐loss attempts during the middle years of life ...
Shenbagam Dewar
wiley   +1 more source

Molecular features responsible for the absence of immunoglobulin heavy chain protein synthesis in an IgH− subgroup of multiple myeloma [PDF]

, 2000
Tomasz Szczepański, Mars B. van ’t Veer, Ingrid L. M. Wolvers‐Tettero, Anton W. Langerak, Jacques J. M. van Dongen   +4 more
openalex   +2 more sources

Hypertrophic cardiomyopathy unveiling multiple myeloma: A diagnostic challenge. [PDF]

Radiol Case Rep
Nour El Houda L, Marwa B, El Ouafi N, Ismaili N.   +3 more
europepmc   +1 more source

C-reactive protein and beta-2 microglobulin produce a simple and powerful myeloma staging system [PDF]

, 1992
Régis Bataille, Mario Boccadoro, Bernard Klein, BrianG.M. Durie, Alessandro Pileri   +4 more
openalex   +1 more source