Biomarkers of Cellular Senescence in Type 2 Diabetes Mellitus
In cohorts of lean controls, obese participants without Type 2 Diabetes Mellitus (T2DM) and obese T2DM participants, we find that T‐cell expression of senescence biomarkers is altered only in the T2DM participants and not with obesity alone. Moreover, high T‐cell p16 expression in the T2DM participants is associated with impaired bone cortical indices.
Caroline Hoong+9 more
wiley +1 more source
Reassessment of the relationship between M-protein decrement and survival in multiple myeloma [PDF]
Martin Palmer+3 more
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Individuals who may develop multiple myeloma within 5 years. Stage I (left) identifies patient and control groups and variables that differ between them. Stage II (middle) develops a complex SGBOOST model to predict future MM patients. Stage III (right) develops a simplified model.
Moshe Mittelman+8 more
wiley +1 more source
Separation of human myeloma cells from bone marrow aspirates in multiple myeloma and their proliferation and M-protein secretion in vitro [PDF]
Koji Iwato+5 more
openalex +1 more source
The progression of multiple myeloma is regulated by LILRB1 via the GATA2–SAGE1 pathway
Summary Multiple myeloma (MM) is a haematological malignancy characterized by the clonal expansion of plasma cells within the bone marrow, thus resulting in the overproduction of monoclonal immunoglobulins. Despite the availability of various immunotherapeutic strategies, patient survival rates remain disappointingly low, thus underscoring the need for
Chiqi Chen+8 more
wiley +1 more source
MAFB: a key regulator of myeloid commitment involved in hematological diseases. [PDF]
Ventura AB+7 more
europepmc +1 more source
The circular dichroism of phosphocholine-specific mouse hybridoma and myeloma proteins: Unusual properties of the hybridoma protein 101.6g6 [PDF]
N. Martin Young+2 more
openalex +1 more source
Polymorphisms in Necroptosis Pathway Genes: Novel Prognostic Markers for Multiple Myeloma Treatment Outcomes. [PDF]
Sokołowski M+4 more
europepmc +1 more source
Thymine and guanine base specificity of human myeloma proteins with anti-DNA activity. [PDF]
Moncef Zouali, B. David Stollar
openalex +1 more source
Impact of proteostasis workload on sensitivity to proteasome inhibitors in multiple myeloma. [PDF]
Sedlacek J.
europepmc +1 more source