Results 191 to 200 of about 87,373 (338)

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng, Jasper F. Ooms, Erik H. J. Danen, Laura H. Heitman   +3 more
wiley   +1 more source

Dynamic monitoring of M-protein quantification by immunotyping using capillary zone electrophoresis during the chemotherapy of patients with multiple myeloma. [PDF]

Sci Rep
Jia Z, Lu Q.
europepmc   +1 more source

Structure-function relations in phosphorylcholine-binding mouse myeloma proteins.

, 1977
Andrew M. Goetze, John H. Richards
openalex   +1 more source

Streptococcus pyogenes type M12 protein shows selective binding to some human immunoglobulin G3 myeloma proteins [PDF]

, 1994
Peter Johansson, Christine C. Malone, Ralph C. Williams, Debbie S. Retnoningrum, P. Patrick Cleary   +4 more
openalex   +1 more source

A Myeloma Protein with Antibody Activity

Cold Spring Harbor Symposia on Quantitative Biology, 1967
C. Kirk Osterland, J. Russell Little, Herman N. Eisen, Ernest S. Simms   +3 more
openaire   +2 more sources

Cancer‐Type‐Specific DNA Methylation Is a Source of Vulnerability in Liver Cancer Cells

Cancer Science, EarlyView.
We profiled genome‐wide DNA methylation in 1165 human cancer cell lines representing 25 cancer types and identified 73 genes as potential liver cancer‐specific methylation‐silenced genes. We selected ASNS, BCAT2, FXYD5, and NQO1 genes for further experimental analysis and demonstrated that aberrant methylation of BCAT2 contributes to the vulnerability ...
Karen Minowa, Miho Seki, Yui Nagai, Satoshi Yamashita   +3 more
wiley   +1 more source

Idiotypic protein‐pulsed dendritic cell vaccination in multiple myeloma [PDF]

, 1999
Seah H. Lim, R Bailey-Wood
openalex   +1 more source

Immunosuppressive Effects of Multiple Myeloma‐Derived Extracellular Vesicles Through T Cell Exhaustion

Cancer Science, EarlyView.
Extracellular vesicles (EVs) derived from myeloma cells could potentially induce T cell exhaustion via the increase of the frequency of immune checkpoint marker‐positive CD8+ T cells and might thereby suppress T cell function. In addition, this immune escape mechanism from cytotoxic T cells is supported by the findings on SPHK1/S1P signaling from SPHK1‐
Shinya Hagiwara, Masaki Ri, Toru Ebina, Yoshiaki Marumo, Tomoyuki Nakamura, Kentaro Hirade, Takahiro Nakashima, Arisa Asano, Shiori Kinoshita, Tomotaka Suzuki, Tomoko Narita, Ayako Masaki, Hirokazu Komatsu, Shinsuke Iida   +13 more
wiley   +1 more source

Mass Spectrometry-Based Proteomics in Clinical Diagnosis of Amyloidosis and Multiple Myeloma: A Review (2012-2024). [PDF]

J Mass Spectrom
Kratka K, Sistik P, Olivkova I, Kusnierova P, Svagera Z, Stejskal D.   +5 more
europepmc   +1 more source

Targeting myeloma metabolism: How abnormal metabolism contributes to multiple myeloma progression and resistance to proteasome inhibitors

Neoplasia: An International Journal for Oncology Research
Multiple myeloma is a hematological malignancy that has evolved from antibody-secreting B lymphocytes. Like other types of cancers, myeloma cells have acquired functional capabilities which are referred to as “Hallmarks of Cancer”, and one of their most ...
Xiang Zhou, Rui He, Wei-Xin Hu, Saiqun Luo, Jingping Hu   +4 more
doaj