Results 191 to 200 of about 5,867,860 (378)

MiR-379 inhibits proliferation and induces apoptosis in multiple myeloma by targeting Y-box binding protein 1

, 2020
Yunyun Wang, Dexiang Ji, Guoan Chen
openalex   +2 more sources

Machine Learning for Predictive Modeling in Nanomedicine‐Based Cancer Drug Delivery

Med Research, EarlyView.
The integration of AI/ML into nanomedicine offers a transformative approach to therapeutic design and optimization. Unlike conventional empirical methods, AI/ML models (such as classification, regression, and neural networks) enable the analysis of complex clinical and formulation datasets to predict optimal nanoparticle characteristics and therapeutic
Rohan Chand Sahu, Sanchit Arora, Dinesh Kumar, Ashish Kumar Agrawal   +3 more
wiley   +1 more source

[Multiple myeloma with biclonal M protein: 6 cases report and literatures review].

, 2016
Qian Yang, J Hou, W M Chen, Xiao‐Jun Huang, Jin Lu   +4 more
openalex   +2 more sources

Myeloma proteins as tumor-specific transplantation antigens.

Proceedings of the National Academy of Sciences of the United States of America, 1972
R. Lynch, R. Graff, S. Sirisinha, E. Simms, H. Eisen   +4 more
semanticscholar   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

Protein arginine methyltransferase 5 has prognostic relevance and is a druggable target in multiple myeloma

, 2017
Annamaria Gullà, Teru Hideshima, Giada Bianchi, Mariateresa Fulciniti, Mehmet Samur, Jun Qi, Y-T Tai, Takeshi Harada, Eugenio Morelli, Nicola Amodio, Ruben D. Carrasco, Pierosandro Tagliaferri, Nikhil C. Munshi, Pierfrancesco Tassone, Kenneth C. Anderson   +14 more
openalex   +1 more source

Monovalent cations and the cut-off of host-cell protein synthesis in mouse myeloma cells infected with an alphavirus [PDF]

, 1979
K.P. Cusack
openalex   +1 more source

Immunochemical analysis of the cross-reacting idiotypes of mouse myeloma proteins with anti-dextran activity and normal anti-dextran antibody.

Proceedings of the National Academy of Sciences of the United States of America, 1973
D. Carson, M. Weigert
semanticscholar   +1 more source

Neurological Peculiarities of POEMS Syndrome: Experience From a Brazilian University Center

Muscle &Nerve, EarlyView.
ABSTRACT Aim Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome is a rare paraneoplastic syndrome associated with significant neurologic morbidity. Better understanding of the manifestations of this disease is crucial to early diagnosis and improvement of prognosis.
Renan Fabri Rosenstein, Jose Pedro Soares Baima, Thales Dalessandro Meneguin Pereira, Gracia Aparecida Martinez, Carlos Otto Heise, Angelina Maria Martins Lino   +5 more
wiley   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source