Results 211 to 220 of about 76,403 (315)

High-Throughput Drug Screening of Clear Cell Ovarian Cancer Organoids Reveals Vulnerability to Proteasome Inhibitors and Dinaciclib and Identifies AGR2 as a Therapeutic Target. [PDF]

Cancer Res Commun
Yoshimura T, Kamatani T, Ookubo A, Takahashi M, Itoh M, Ebisudani T, Masugi Y, Toyonaga T, Hamamoto J, Saotome K, Sakai K, Yoshihama T, Moritoki N, Shibata S, Yasuda H, Sato T, Sato TA, Aoki D, Yamagami W, Tsunoda T, Chiyoda T.   +20 more
europepmc   +1 more source

Daratumumab and isatuximab differentially affect CD38 detection on plasma cells in myeloma: Anti‐CD38 nanobody (clone JK36) and CD319 combination improve flow cytometric identification of plasma cells after targeted therapies

British Journal of Haematology, EarlyView.
Daratumumab and isatuximab differentially affect plasma cell identification by anti‐CD38 detection antibodies. HB‐7 and JK36 bind to CD38 epitopes E1 and E3, respectively, and co‐staining of plasma cells in the absence of CD38‐directed drugs results in a diagonal staining pattern (top left).
Afshin Shameli, Tori Catey, Valerie Woodings, Orrin Koepke, Jonathan R. Fromm, Sindhu Cherian   +5 more
wiley   +1 more source

Revolutions at the frontline of multiple myeloma treatment: lessons and challenges to finding a cure. [PDF]

Front Oncol
Kort J, Rivera A, Senigarapu S, Driscoll JJ.   +3 more
europepmc   +1 more source

PROTEINS IN MULTIPLE MYELOMA

Journal of Biological Chemistry, 1957
Frank W. Putnam, Aiko Miyake
openaire   +3 more sources

ZIP10 as a potential therapeutic target in acute myeloid leukaemia

British Journal of Haematology, EarlyView.
Increased intracellular zinc levels in acute myeloid leukaemia blasts with upregulated expression of zinc influx transporters ZIP6 and ZIP10. Targeting ZIP10 with a surface antibody represents a potential therapeutic strategy. Created in BioRender. Rolles, B. (2025) https://BioRender.com/bwrtof1.
Benjamin Rolles, Nicolas Chatain, Richard Görg, Margherita Vieri, Nora Tillmann‐Tröster, Marcel G. Bourgeois, Deborah Christen, Jeanette Walter, Addison C. Hillerbrand, Kyle A. Romine, Kathryn M. Taylor, Jens Bertram, Edgar Jost, Steffen Koschmieder, Fabian Beier, Maximilian Stahl, Tim H. Brümmendorf, Lothar Rink, Inga Wessels   +18 more
wiley   +1 more source

Screening for monoclonal gammopathy of undetermined significance is contraindicated. [PDF]

Br J Haematol
Singh G.
europepmc   +1 more source

Acute kidney injury after chimeric antigen receptor T‐cell therapy is associated with inferior survival in patients with relapsed/refractory large B‐cell lymphoma

British Journal of Haematology, EarlyView.
Summary Baseline risk factors for acute kidney injury (AKI) during chimeric antigen receptor T‐cell (CAR‐T) therapy are not well described. Hence, we evaluated the incidence and risk factors associated with AKI among patients undergoing CAR‐T for relapsed/refractory large B‐cell lymphoma. Among 155 patients, 28 (18%) developed AKI with a median time‐to‐
John Sharp, Qiuhong Zhao, Timothy J. Voorhees, David A. Bond, Yazeed Sawalha, John Reneau, Audrey Sigmund, Walter Hanel, Lalit Sehgal, Lapo Alinari, Robert Baiocchi, Jonathan E. Brammer, Kami Maddocks, Beth Christian, Evandro Bezerra, Nathan Denlinger, Sumithira Vasu, Marcos De Lima, Jason Prosek, Narendranath Epperla   +19 more
wiley   +1 more source

Sensitivity to an inhibitor of translation elongation in solid and hematologic cancers. [PDF]

Sci Rep
Gomes N, Frederick B, Tentler J, Su TT.
europepmc   +1 more source

Clusterin and pentraxin 3 are markers of severity during febrile neutropenia in adults with haematological malignancies receiving intensive chemotherapy

British Journal of Haematology, EarlyView.
During febrile neutropenia in patients with haematological malignancies, pentraxin 3 (PTX3), a soluble innate immunity receptor, increases with severe sepsis, while clusterin, a chaperon protein involved in extracellular histones clearance, decreases in patients with quick SOFA score (qSOFA) ≥2.
Coralie Mallebranche, Carole Mosnier, Corentin Orvain, Jérémie Riou, Sylvain Thepot, Pascale Pignon, Simon Blanchard, Nathalie Tortevoie, Isabelle Pellier, Mathilde Hunault‐Berger, Pascale Jeannin, Yves Delneste, Aline Schmidt‐Tanguy, Céline Beauvillain   +13 more
wiley   +1 more source

Dynamic monitoring of M-protein quantification by immunotyping using capillary zone electrophoresis during the chemotherapy of patients with multiple myeloma. [PDF]

Sci Rep
Jia Z, Lu Q.
europepmc   +1 more source