Sperm protein 17 (Sp17) in multiple myeloma: opportunity for myeloma-specific donor T cell infusion to enhance graft-versus-myeloma effect without increasing graft-versus-host disease risk [PDF]
Maurizio Chiriva‐Internati+5 more
openalex +1 more source
Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang+4 more
wiley +1 more source
Prognostic impact of dynamic changes of type I melanoma antigen gene proteins CT7 (<i>MAGE-C1/CT7</i>) transcripts in multiple myeloma. [PDF]
Dou X+10 more
europepmc +1 more source
Protein kinase C δ and η isoenzymes control the shedding of the interleukin 6 receptor α in myeloma cells [PDF]
Wilfrid Thabard+3 more
openalex +1 more source
Tumour Cell Size Control and Its Impact on Tumour Cell Function
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley +1 more source
Exploring the role of circulating proteins in multiple myeloma risk: a Mendelian randomization study. [PDF]
Lee MA+5 more
europepmc +1 more source
Antisense inhibition of macrophage inflammatory protein 1-α blocks bone destruction in a model of myeloma bone disease [PDF]
Sun Jin Choi+6 more
openalex +1 more source
ABSTRACT The treatment of elderly, nonfit acute myeloid leukemia (AML)/MDS patients with relapsed/refractory (R/R) disease remains challenging. As histone demethylase LSD1 (KDM1A) is a rational therapeutic target in AML, we conducted a phase I trial (“rolling‐six design”) with the LSD1 inhibitor tranylcypromine (TCP, dose levels [DL] 20, 40, 60, 80 mg ...
Michael Kruszewski+22 more
wiley +1 more source
A Rare Type of Myeloma: A Case of Monoclonal IgD-Lambda. [PDF]
Kaya R+3 more
europepmc +1 more source