Results 231 to 240 of about 87,373 (338)
ABSTRACT Autologous hematopoietic stem cell transplantation (AHSCT) is the treatment for myeloma and lymphoma. posttreatment, significant nutritional and medical issues and malnutrition assessed by Subjective Global Assessment (SGA) arise. No established effective treatment for using either parenteral (PN) or enteral routes (EN) to improve nutritional ...
Janet Madill+9 more
wiley +1 more source
Myeloma mesenchymal stem cells' bioenergetics afford a novel selective therapeutic target. [PDF]
Komemi O+7 more
europepmc +1 more source
Physical and functional interactions between LDLR family members and CXCR4 in breast cancer
Here, we demonstrate that members of the low‐density lipoprotein receptor (LDLR) family can regulate C‐X‐C chemokine receptor type 4 (CXCR4) signaling and therefore affect CXCR4‐induced breast cancer metastasis. We found that very low‐density lipoprotein receptor (VLDLR), low‐density lipoprotein receptor‐related protein 8 (LRP8) and apolipoprotein E ...
Jiankang Zhang+7 more
wiley +1 more source
A novel indirubin- 3-monoxime derivative I3MV- 8b exhibits remarkable cytotoxicity against multiple myeloma by targeting TRIM28. [PDF]
Fang T+13 more
europepmc +1 more source
Extracellular vesicles in multiple myeloma: pathogenesis and therapeutic application
Multiple myeloma is characterised by the clonal proliferation of plasma cells in the bone marrow. Extracellular vesicles (EVs) are a key component of cell‐to‐cell communication within the bone marrow microenvironment, promoting tumour growth, bone remodelling, immune modulation, angiogenesis and therapeutic resistance.
Chloe Wylie+3 more
wiley +1 more source
Diagnosis and Management of Monoclonal Gammopathy of Undetermined Significance: A Review. [PDF]
Liu Y, Parks AL.
europepmc +1 more source
TENT5C is a suppressor of ERα and GR transcriptional activation. A specific LXXLL motif in TENT5C, absent in the other members of the TENT5 subfamily, mediates a stable interaction with the Ligand Binding Domain of ERα but not with that of GR.
Yin Li+5 more
wiley +1 more source
MYC alterations in multiple myeloma: Genetic insights and prognostic impact. [PDF]
Cristóbal-Vargas S+2 more
europepmc +1 more source
Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley +1 more source