Results 281 to 290 of about 5,867,860 (378)

Continued M Protein Responses Beyond Day 100 After Autologous Transplantation for Myeloma: Implications for Post Transplant Strategies

, 2009
Shaji Kumar, Angela Dispenzieri, Martha Q. Lacy, Suzanne R. Hayman, Francis K. Buadi, David Dingli, S. Vincent Rajkumar, Mark R. Litzow, Morie A. Gertz   +8 more
openalex   +1 more source

Epidemiology of Monoclonal Gammopathies in Sub‐Saharan Africa: A Systematic Review and Meta‐Analysis of MGUS and Multiple Myeloma

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) are reported to occur more frequently in Black populations, particularly African Americans. However, despite Sub‐Saharan Africa (SSA) being home to the largest Black population globally, epidemiological data on MGUS and MM in the region remain scarce.
Iyanuloluwa S. Ojo, Olurotimi John Badero, Toluwalope Olawale Oluwalana, Nicholas Aderinto, Faridat Ibidun, Onur Oral, Emmanuel Oyesiji, Evelyn Faith Ogungbemi   +7 more
wiley   +1 more source

NSD Family-Mediated H3K36 Methylation in Human Cancer: Mechanisms and Therapeutic Opportunities. [PDF]

Biomedicines
Park JE, Nguyen MT, Kim J, Lee CH, Nam JW, Chung H, Park MK, Lee JY.   +7 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Serum proteome profiling identified thrombospondin-1 and lactoferrin as biomarkers of relapsed multiple myeloma. [PDF]

Front Med (Lausanne)
Wu X, Guo J, Deng H, Chen W.
europepmc   +1 more source

Extramedullary Disease—Achilles Heel in Myeloma?

American Journal of Hematology, Volume 101, Issue 3, Page 521-536, March 2026.
ABSTRACT Despite advances in therapy, extramedullary disease (EMD) remains an aggressive form of multiple myeloma associated with poor outcomes. Patients with true EMD, in which plasmacytomas have become completely independent of bone, have a particularly poor prognosis. The pathogenesis of EMD is driven by complex mechanisms involving loss of adhesion
Shaji Kumar, Joshua Richter, Saad Z. Usmani, Yael C. Cohen, Jing Christine Ye, María‐Victoria Mateos, Vania Hungria, Elena Zamagni   +7 more
wiley   +1 more source

Targeting of SKP2 to combat drug resistance in multiple myeloma. [PDF]

Sci Rep
Faruq O, Ngo J, Iyer D, Nesson J, Shrestha M, Chang H.   +5 more
europepmc   +1 more source

Metastatic Spine Disease Alters Vertebral Load‐To‐Strength Ratios in Cancer Patients Compared to Healthy Individuals

JOR SPINE, Volume 9, Issue 1, March 2026.
This study investigated the effect of spinal bone metastasis (BM) on the biomechanical environment of the spine through estimates of load, strength, and the load‐to‐strength ratio (LSR). Our study suggests that task‐specific differences related to cancer, lesion type, and vertebral location differentially affect the biomechanical environment of the ...
Dennis E. Anderson, Mario Keko, Joanna James, Brett T. Allaire, David Kozono, Patrick F. Doyle, Heejoo Kang, Sarah Caplan, Tracy Balboni, Alexander Spektor, Mai Anh Huynh, Mary L. Bouxsein, David B. Hackney, Ron N. Alkalay   +13 more
wiley   +1 more source

Automated detection of free monoclonal light chains by enhanced-sensitivity modified immunofixation electrophoresis with antisera against free light chains. [PDF]

Lab Med
Singh G, Saldaña EJ, Spencer J, Bollag RJ.   +3 more
europepmc   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, Volume 46, Issue 2, Page 352-381, March 2026.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source