Results 121 to 130 of about 65,744 (296)

Reirradiation: Standards, challenges, and patient‐focused strategies across tumor types

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract Reirradiation (reRT), defined as administering a course of radiation therapy to a specific area previously irradiated, is an evolving treatment strategy for locoregionally recurrent cancer that offers significant potential and poses inherent challenges.
Arnaud Beddok, Jonas Willmann, Anna Embring, Ane L. Appelt, Panagiotis Balermpas, Kevin Chua, J. Isabelle Choi, Bernice Simone Elger, Dorota Gabrys, Peter Hoskin, Maximilian Niyazi, David Pasquier, Kelly Paradis, Orit Kaidar‐Person, Corien Plaisier, Nicole C. Schmitt, Conor E. Steuer, Juliette Thariat, Sue S. Yom, Philip Poortmans, Eliana Vasquez Osorio, Nicolaus Andratschke   +21 more
wiley   +1 more source

Canine NAPEPLD-associated models of human myelin disorders [PDF]

, 2018
Canine leukoencephalomyelopathy (LEMP) is a juvenile-onset neurodegenerative disorder of the CNS white matter currently described in Rottweiler and Leonberger dogs. Genome-wide association study (GWAS) allowed us to map LEMP in a Leonberger cohort to dog
Bannasch, D L, Becker, D, Bellekom, S R, Cassidy, J P, Drogemuller, C, Drogemuller, M, Ekenstedt, K J, Fischer, A, Flegel, T, Furrow, E, Henke, D, Jagannathan, V, Kelly, P A, Leegwater, P A J, Letko, A, Lucot, K, Mandigers, P J J, Martineau, H, Matiasek, K, Mickelson, J R, Minor, K M, Muir, C F, Oevermann, A, Patterson, E E, Platt, S R, Priestnall, S L, Putschbach, K, Shelton, G D, Stassen, QEM   +28 more
core   +5 more sources

Natural History and Diagnostic Findings in an Adult Man Diagnosed With Attenuated Krabbe Disease

American Journal of Medical Genetics Part A, Volume 197, Issue 7, July 2025.
ABSTRACT Krabbe disease (KD), or globoid cell leukodystrophy, is a rare autosomal recessive lysosomal storage disorder caused by a deficiency in galactocerebrosidase (GALC), leading to psychosine (galactosylsphingosine) accumulation and myelin damage.
Eamon P. McCarron, Andrew Oldham, Amit Herwadkar, Sarah Jenkinson, Christopher Campbell, Kate Neal, Heather J. Church, James A. Cooper, Karolina M. Stepien   +8 more
wiley   +1 more source

Outcomes of Fusions From the Cervical Spine to the Pelvis. [PDF]

, 2018
Study designRetrospective cohort study.ObjectiveDetermine the indications, complications, and clinical outcomes in patients requiring fusions from the cervical spine to the pelvis.
Albert, Todd J, Ames, Christopher P, Boachie-Adjei, Oheneba, Burch, Shane, Deviren, Vedat, Iyer, Sravisht, Kim, Han Jo, Kleinberg, Eric O, Lenke, Lawrence G, Mizutani, Jun, Nemani, Venu M, Protopsaltis, Themistocles S, Scheer, Justin K, Smith, Justin S, Theologis, Alexander   +14 more
core   +1 more source

Pathobiology of cervical spondylotic myelopathy

European spine journal, 2015
In this narrative review, we aim to outline what is currently known about the pathophysiology of cervical spondylotic myelopathy (CSM), the most common cause of spinal cord dysfunction.
Spyridon K. Karadimas, G. Gatzounis, M. Fehlings   +2 more
semanticscholar   +1 more source

High‐resolution and high‐fidelity diffusion tensor imaging of cervical spinal cord using 3D reduced‐FOV multiplexed sensitivity encoding (3D‐rFOV‐MUSE)

Magnetic Resonance in Medicine, Volume 94, Issue 1, Page 166-182, July 2025.
Abstract Purpose To develop a 3D isotropic high‐resolution and high‐fidelity cervical spinal cord DTI technique for addressing the current challenges existing in 2D cervical spinal cord DTI. Methods A 3D multi‐shot DWI acquisition and reconstruction technique was developed by combining 3D multiplexed sensitivity encoding (3D‐MUSE) with two reduced FOV ...
Chenglang Yuan, Shihui Chen, Liyuan Liang, Xiaorui Xu, Hailin Xiong, Yi Li, Tianbaige Liu, Nan‐Kuei Chen, Hing‐Chiu Chang   +8 more
wiley   +1 more source

Copper deficiency, a new triad: anemia, leucopenia, and myeloneuropathy

Journal of Community Hospital Internal Medicine Perspectives, 2017
Clinical copper deficiency is now more frequently recognized. Hematologically, it can present as anemia (microcytic, normocytic, or macrocytic) and neutropenia. Thrombocytopenia is relatively rare.
Shoaib M. Wazir, Ibrahim Ghobrial
doaj   +1 more source

Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects. [PDF]

, 2016
Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of ...
Blackburn, Elizabeth, Bruhn, Roberta, Lee, Tzong-Hae, Lin, Jue, Murphy, Edward L, Usadi, Benjamin   +5 more
core   +3 more sources

First Description of Atypical Aspergillus floccosus as Cause of Canine Systemic Aspergillosis With Discospondylitis

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
A case of disseminated aspergillosis in dog was described due to an atypical strain of Aspergillus floccosus. Aspergillosis should be considered in the differential diagnosis of dogs with neurological signs and nonspecific changes in CBC or CMP, particularly in German Shepherd dogs.
Talita Bordoni, Samuel Okonji, Filippo Maria Dini, Monica Cricca, Gualtiero Gandini, Monica Caffara, Roberta Galuppi   +6 more
wiley   +1 more source

Frequency estimation of disease-causing mutations in the Belgian population of some dog breeds, part 2 : retrievers and other breed types [PDF]

, 2016
A Belgian population of ten breeds with a low to moderately low genetic diversity or which are relatively popular in Belgium, i.e. Bichon frise, Bloodhound, Bouvier des Flandres, Boxer, Cavalier King Charles spaniel, Irish setter, Papillon, Rottweiler ...
Beckers, Evy, Peelman, Luc, Ronsyn, L, Van Poucke, Mario   +3 more
core