Results 131 to 140 of about 145,768 (387)
Redox properties of myeloperoxidase
Redox Report, 2003 The heme-containing enzyme myeloperoxidase (MPO) is secreted from polymorphonuclear leukocytes and monocytes. It is involved in host defence and inflammation by oxidation of numerous small molecules. This review summarises our current results on the determination of redox properties of all intermediates involved in the halogenation and peroxidase cycle
Paul G. Furtmüller +2 more
openaire +3 more sources
Advanced Science, EarlyView.Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou +15 more
wiley +1 more source
Urinary CE-MS peptide marker pattern for detection of solid tumors [PDF]
, 2018 Urinary profiling datasets, previously acquired by capillary electrophoresis coupled to mass-spectrometry were investigated to identify a general urinary marker pattern for detection of solid tumors by targeting common systemic events associated with ...
Belczacka, Iwona +8 more
core +2 more sources
Role of Myeloperoxidase in Patients with Chronic Kidney Disease
Oxidative Medicine and Cellular Longevity, 2016 Chronic kidney disease (CKD) is a worldwide public health problem. Patients with CKD have a number of disorders in the organism, and the presence of oxidative stress and systemic inflammation in these patients is the subject of numerous studies.
B. Kisić +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao +13 more
wiley +1 more source
Evolution of pulmonary inflammation and nutritional status in infants and young children with cystic fibrosis [PDF]
, 2011 Introduction Improved nutrition is the major proven benefit of newborn screening programmes for cystic fibrosis (CF) and is associated with better clinical outcomes.
Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF) +6 more
core +1 more source
Journal of clinical biochemistry and nutrition, 2016 Myeloperoxidase is an inflammatory enzyme that generates reactive hypochlorous acid in the presence of hydrogen peroxide and chloride ion. However, this enzyme also uses bromide ion or thiocyanate as a substrate to form hypobromous or hypothiocyanous ...
Y. Kato
semanticscholar +1 more source
Theranostic Toolbox for Neutrophil Functionalization
Advanced Science, EarlyView.Here, neutrophil‐specific fluorine nanoparticles additionally equipped with either activating or inhibiting peptides for a background‐free 19F MRI‐based nanotheranostic approach are engineered. It is demonstrated that this approach is suitable to visualize and concomitantly direct neutrophil functionality depending on the specific requirements to ...
Pascal Bouvain +11 more
wiley +1 more source
Inflammatory bowel disease-specific autoantibodies in HLA-B27-associated spondyloarthropathies: Increased prevalence of ASCA and pANCA [PDF]
, 2004 Aims: An association between inflammatory bowel disease (IBD) and spondyloarthropathies (SpA) has repeatedly been reported. The aim of the present study was to investigate whether serologic markers of IBD, e. g.
Brumberger, V. +7 more
core +1 more source
Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease.
Brain : a journal of neurology, 2015 Impaired mitochondrial function, oxidative stress and formation of excessive levels of reactive oxygen species play a key role in neurodegeneration in Parkinson's disease.
A. Jucaite +15 more
semanticscholar +1 more source