Results 111 to 120 of about 87,247 (298)

Effective Performance of the 2022 American College of Rheumatology/EULAR Classification Criteria for Antineutrophil Cytoplasmic Antibody–Associated Vasculitis in Pediatric Patients: An ARChiVe Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective To assess the 2022 American College of Rheumatology (ACR)/EULAR classification criteria for antineutrophil cytoplasmic antibody–associated vasculitis (AAV) in children with chronic small‐to‐medium vessel vasculitis. Methods A cohort of 574 patients, identified by physician's diagnosis (MD‐diagnosis) in A Registry of Childhood Vasculitis, was ...
David A. Cabral   +41 more
wiley   +1 more source

Myeloperoxidase and Inflammatory Bowel Disease

open access: yes, 2020
Examining the relationship of neutrophil extracellular traps (NETs) in clinical IBD samples and the role of myeloperoxidase in modulating the gut ...
Chami, Belal
core  

Neutrophil myeloperoxidase (MPO) content.

open access: yes, 2012
MPO =  myeloperoxidase. MFI: mean fluorescence intensity revealed within neutrophils (CD45+, CD66b+, CD14− cells). ACS: acute coronary syndromes. STEMI: segment T elevated myocardial infarction. NSTEMI: no STEMI. UA: unstable angina.
Filippo Figini (155915)   +19 more
core   +1 more source

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci   +10 more
wiley   +1 more source

Biosynthesis of human myeloperoxidase

open access: yesArchives of Biochemistry and Biophysics, 2018
Members of Chordata peroxidase subfamily [1] expressed in mammals, including myeloperoxidase (MPO), eosinophil peroxidase (EPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO), express conserved motifs around the heme prosthetic group essential for their activity, a calcium-binding site, and at least two covalent bonds linking the heme group to ...
openaire   +3 more sources

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

open access: yesBMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu   +7 more
wiley   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

open access: yesBMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue   +4 more
wiley   +1 more source

Improved cardiac patient management through cardiac markers [PDF]

open access: yesJournal of Medical Biochemistry, 2008
Cardiac markers enable the diagnosis and characterization of cardiac diseases. While the highly sensitive troponin assay is specific for myocardial infarction, myeloperoxidase is a powerful tool for early determination of plaque formation.
Herzig Birgit
doaj  

Estudo do efeito anti-inflamatório da Rosmarinus officinalis L. utilizando o modelo da pleurisia induzida pela carragenina, em camundongos [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2013.Introdução: Rosmarinus officinalis L.
Rosa, Julia Salvan da
core  

Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy

open access: yesBiotechnology Progress, EarlyView.
Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung   +5 more
wiley   +1 more source

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