Results 151 to 160 of about 145,768 (387)

Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage.

Free Radical Biology & Medicine, 2021
C. Hawkins, M. Davies
semanticscholar   +1 more source

Proteinase 3-ANCA Vasculitis versus Myeloperoxidase-ANCA Vasculitis.

Journal of the American Society of Nephrology, 2015
In patients with GN or vasculitis, ANCAs are directed against proteinase 3 (PR3) or myeloperoxidase (MPO). The differences between PR3-ANCA-associated vasculitis (AAV) and MPO-AAV described in the past have been supplemented during the last decade.
M. Hilhorst, P. van Paassen, J. C. Tervaert   +2 more
semanticscholar   +1 more source

The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression

Advanced Science, EarlyView.
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu, Mengxi Xiu, Shijun Yu, Zhiqin Chen, Yandong Li, Yong Gao   +5 more
wiley   +1 more source

Chlorinated lipid species in activated human neutrophils: lipid metabolites of 2-chlorohexadecanal

Journal of Lipid Research, 2010
Neutrophils are important in the host response against invading pathogens. One chemical defense mechanism employed by neutrophils involves the production of myeloperoxidase (MPO)-derived HOCl.
Dhanalakshmi S. Anbukumar, Laurie P. Shornick, Carolyn J. Albert, Melissa M. Steward, Raphael A. Zoeller, William L. Neumann, David A. Ford   +6 more
doaj  

Role of the Phagocyte in Host-Parasite Interactions XII. Hydrogen Peroxide-Myeloperoxidase Bactericidal System in the Phagocyte [PDF]

, 1967
R. J. McRipley, Anthony J. Sbarra
openalex   +1 more source

Adipose Tissue Macrophages as Initiators of Exacerbated Periodontitis in Estrogen‐Deficient Environments via the Amplifier Extracellular Vesicles

Advanced Science, EarlyView.
Chronic systemic inflammation, worsened by estrogen deficiency, underlies and exacerbates periodontitis. Proinflammatory macrophages within visceral adipose tissue are hyperactivated due to hyper‐DNA methylation, releasing small extracellular vesicles (sEVs) similar to those of their parent cells.
Danfeng Li, Tian Yang, Yuqian Li, Xinwei Lyu, Cheng Hu, Jiayin Yan, Jiali Tan   +6 more
wiley   +1 more source

Nitroblue Tetrazolium (NBT)‐Dye Test and the Myeloperoxidase Reaction of Human Leukocytes [PDF]

, 1974
Kenji Okuda, I Tadokoro, Yoshikuni Noguchi, Kyoko Okuda   +3 more
openalex   +1 more source

Cancer Cell‐Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA

Advanced Science, EarlyView.
Venous thromboembolism (VTE) is a major threat to cancer patients. Cancer‐derived large extracellular vesicles deliver CYBA (p22phox) to neutrophils, triggering reactive oxygen species (ROS) and citrullinated histone H3 (citH3) formation. This drives neutrophil extracellular traps formation (NETosis), elevating VTE risk.
Xiangji Li, Yingjiao Ju, Chenjie Xu, Shixiang Ma, Lan Sun, Qingdong Guo, Mingyuan Liu, Yibin Xie, Li Min   +8 more
wiley   +1 more source

Identification of glutathione adducts of α-chlorofatty aldehydes produced in activated neutrophils

Journal of Lipid Research, 2015
α-Chlorofatty aldehydes (α-ClFALDs) are produced by hypochlorous acid targeting plasmalogens during neutrophil activation. This study investigated the reaction of the α-chlorinated carbon of α-ClFALD with the nucleophile, GSH.
Mark A. Duerr, Rajeev Aurora, David A. Ford   +2 more
doaj  

Hemolysis and iodination of erythrocyte components by a myeloperoxidase- mediated system [PDF]

, 1975
SJ Klebanoff, Robert A. Clark
openalex   +1 more source