Recent Advances in Fluorescent Probes for Imaging Enzyme Activity in NETosis
Fluorescent probes enable real‐time visualization of neutrophil effector functions. This review summarizes current probe design strategies and emerging tools for imaging key enzymatic activities, with emphasis on mechanisms underlying NETosis, a lytic form of neutrophil extracellular trap (NET) formation. We discuss current limitations, challenges, and
Enebie Ramos Cáceres +2 more
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Microscopic Polyangiitis After Pulmonary Nontuberculous Mycobacterial Disease: A Case Report and Literature Review. [PDF]
Takahashi H +11 more
europepmc +1 more source
Objective To evaluate the six‐month effectiveness and safety of rituximab biosimilars compared to the originator in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), and outcomes following originator to biosimilar switching. Methods We recruited adults with GPA or MPA treated with the rituximab originator or a biosimilar for ...
Arielle Mendel +14 more
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Systemic toxicity assessment of tissue conditioners modified with nystatin and chlorhexidine in a rat model of denture stomatitis. [PDF]
Moraes GS +8 more
europepmc +1 more source
MSI‐H/dMMR colorectal cancer exhibits a distinct immune‐inflammatory profile characterised by lymphocyte enrichment, reduced tissue MPO/CD8 balance and context‐dependent systemic signals. Evidence synthesis suggests elevated NLR, while local data indicate attenuated inflammatory indices, highlighting discordance between systemic and tissue‐level immune
Yue Huang, Xuefei Chen, Zizhen Xu
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Coexistence of Microscopic Polyangiitis, Systemic Lupus Erythematosus, and Transthyretin Amyloidosis in an Elderly Japanese Patient With Splenic Marginal Zone Lymphoma: An Autopsy Case Report. [PDF]
Nagayama Y +4 more
europepmc +1 more source
The prosthetic group of myeloperoxidase
Wu, N.C., Schultz, J.
openaire +2 more sources
Placental insufficiency is a thromboinflammatory disorder driven by angiogenic imbalance, complement activation, endothelial dysfunction and coagulation dysregulation, leading to microvascular thrombosis, impaired uteroplacental perfusion and adverse maternal and fetal outcomes, including pre‐eclampsia, fetal growth restriction and stillbirth. Abstract
Emmanuel Ifeanyi Obeagu
wiley +1 more source
A Case of Eosinophilic Granulomatosis with Polyangiitis Emerging During Benralizumab Therapy: Successful Management Through a Switch to Mepolizumab Therapy. [PDF]
Saito Y +10 more
europepmc +1 more source
Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu +4 more
wiley +1 more source

