Results 221 to 230 of about 92,132 (290)

Machine learning-based MPO and Lp-PLA2 profiling reveals asthma-predominant inflammatory signature in asthma-COPD overlap. [PDF]

World Allergy Organ J
Liu M, Chen J, Yao J, Zheng Y, Li X, Zhong H, Liu J, Zheng J, Ye R, Huang H, Zheng P, Sun B.   +11 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, Volume 20, Issue 11, Page 2656-2673, November 2026.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Author Response: NETosis Markers such as Citrullinated Histones Myeloperoxidase and Elastase should not be Recommended as Predictors of COVID-19 Severity. [PDF]

Indian J Crit Care Med
Kumar A.
europepmc   +1 more source

Identification of C3d Complement Fragments in Lesional Tissues in ANCA‐Associated Vasculitis

ACR Open Rheumatology, Volume 8, Issue 11, November 2026.
Objective Antineutrophil cytoplasmic antibody–associated vasculitis (AAV) is typically described as “pauci‐immune” due to the absence or weak detection of Igs and complement activation within AAV tissue lesions. However, complement fragments have been recently reported in significant amounts in damaged tissue in AAV, notably in traps formed by ...
Claire Galand, Fei Liu, Katherine A. Vernon, Ravi Vats, Christine Lian, V. Michael Holers, Michael Woodbury, H. Terence Cook, David Cuthbertson, Nader Khalidi, Curry Koening, Carol A. Langford, Carol A. McAlear, Paul A. Monach, Christian Pagnoux, Jason A. Campagna, Stefan Wawersik, Shelia Violette, Peter A. Merkel, for the Vasculitis Clinical Research Consortium   +19 more
wiley   +1 more source

Performance Status as a Prognostic Factor in Japanese Patients With Myeloperoxidase–Antineutrophil Cytoplasmic Antibody–Positive Microscopic Polyangiitis

ACR Open Rheumatology, Volume 8, Issue 11, November 2026.
Objective This observational study investigated the impact of performance status (PS) on prognosis following remission induction therapy in patients with myeloperoxidase (MPO)–antineutrophil cytoplasmic antibody–positive microscopic polyangiitis (MPA).
Tokio Katakura, Ken‐ei Sada, Masayoshi Harigai, Yuki Nakamura, Shouichi Fujimoto, Yukio Yuzawa, Kunihiro Yamagata, Masaki Kobayashi, Tatsuya Atsumi, Takahiko Sugihara, Naoto Tamura, Yoshihiro Arimura, Hirofumi Makino, Izaya Nakaya   +13 more
wiley   +1 more source

Clinical and Immunological Factors Associated with Disease Activity in MPO-ANCA-Associated Vasculitis. [PDF]

Open Access Rheumatol
Chen Y, Shuai Z.
europepmc   +1 more source

Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke

Annals of Neurology, Volume 100, Issue 5, Page 964-978, November 2026.
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary, Jean‐Philippe Desilles, Fatima Zemali, Astride Perrot, Lucas Di Meglio, Sara Zalghout, Jéromine Fasille, Jérémy Neel, Stéphane Loyau, Julien Labreuche, Marie‐Charlotte Bourrienne, Dorothée Faille, François Delvoye, Véronique Ollivier, Sébastien Dupont, Jasmina Rogozarski, Nahida Brikci‐Nigassa, Robert L. Medcalf, Nadine Ajzenberg, Mikael Mazighi, Benoît Ho‐Tin‐Noé, the compoCLOT Study Group   +21 more
wiley   +1 more source

Etanercept-Induced Cutaneous Necrotizing Vasculitis in a Patient With Rheumatoid Arthritis: A Case Report and Literature Review. [PDF]

Cureus
Nouri C, Tahiri L, Rkain H, Kronbi F, Allali F.   +4 more
europepmc   +1 more source

Therapeutic Potential of Propolis in Ulcerative Colitis: A Review of Preclinical Evidence

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review compiles preclinical evidence from studies that investigate the therapeutic potential of propolis extracts derived from different botanical origins, as well as their main bioactive constituents, in the context of ulcerative colitis. The observed beneficial effects are primarily attributed to their antioxidant, immunomodulatory, and anti ...
Thayná Fernandes Barros, Gabriel Gomes Vila Nova, Rosane Nassar Meireles Guerra, Flavia Raquel Fernandes do Nascimento, Afonso Gomes Abreu   +4 more
wiley   +1 more source

Engineered probiotic-mediated palmitoylethanolamide biosynthesis protects against colitis-associated liver injury. [PDF]

Front Pharmacol
Palenca I, Franzin SB, Sarnelli G, Esposito G.   +3 more
europepmc   +1 more source