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Platelet Function, Role in Thrombosis, Inflammation, and Consequences in Chronic Myeloproliferative Disorders [PDF]
Cells, 2021 Platelets are conventionally defined as playing a vital role in homeostasis and thrombosis. This role has over the years transformed as knowledge regarding platelets has expanded to include inflammation, cancer progression, and metastasis.
Lisa Repsold, Anna Margaretha Joubert
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Hereditary myeloproliferative disorders
Haematologica, 2010 Hereditary forms of myeloproliferative disorders (MPD) can be divided into two broad categories. First, inherited syndromes that affect a single lineage with Mendelian inheritance, high penetrance and polyclonal hematopoiesis, and second, inherited predisposition to true MPD, characterized by ...
Radek C. Skoda
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Pulmonary hypertension in patients with chronic myeloproliferative disorders [PDF]
European Respiratory Review, 2015 Pulmonary hypertension (PH) is a major complication of several haematological disorders. Chronic myeloproliferative diseases (CMPDs) associated with pulmonary hypertension have been included in group five of the clinical classification for pulmonary ...
Yochai Adir, Davide Elia, Sergio Harari
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Eosinophilic myeloproliferative disorders. [PDF]
Hematology Am Soc Hematol Educ Program, 2011 AbstractDespite recent attempts to define and classify patients with marked eosinophilia and features consistent with myeloproliferative disease, areas of controversy remain. These are particularly apparent in situations in which multiple lineages are involved in a clonal process and clinical manifestations are overlapping. Although the introduction of
Klion AD.
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A review of current knowledge of myeloproliferative disorders in the horse [PDF]
Acta Veterinaria Scandinavica, 2021 Myeloid disorders are conditions being characterized by abnormal proliferation and development of myeloid lineage including granulocytes (neutrophils, eosinophils and basophils), monocytes, erythroids, and megakaryocytes precursor cells. Myeloid leukemia,
Katy Satué +2 more
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Chorea and Cognitive Impairment in JAK2V617F-Positive Myeloproliferative Disorders: A Case Report and Literature Review [PDF]
Medicina, 2023 Chorea is a hyperkinetic movement disorder, accompanied by dystonia, myoclonus, tics, stereotypies, and tremors. It is characterized by excessive, purposeless movements that are distressing, irregularly timed, and randomly distributed.
Ioana Butnariu +7 more
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Erythromelalgia: An Uncommon Presentation Precipitated by Aspirin Withdrawal [PDF]
Case Reports in Medicine, 2012 Erythromelalgia is a rare disorder frequently associated with myeloproliferative disorders. We describe a case of elderly patient diagnosed with myeloproliferative disorder in remission.
Fatima Khalid +4 more
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Myelodysplastic/myeloproliferative disorders
Haematologica, 2008 Most patients with myelodysplastic syndromes present with anemia, while neutropenia, thrombocytopenia, or both may be found initially or may appear later.[1][1] Therefore cytopenia, frequently pancytopenia (i.e., reduced counts of red blood cells, white blood cells and platelets in peripheral ...
Luca Malcovati, Mario Cazzola
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JAK2 Inhibition: Reviewing a New Therapeutical Option in Myeloproliferative Neoplasms [PDF]
Advances in Hematology, 2012 JAK2 is a tyrosine kinase gene that plays an essential role in the development of normal haematopoiesis. Hyperactivation of JAK2 occurs in myeloproliferative neoplasms by different mechanisms.
Mar Bellido, Peter A. W. te Boekhorst
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Chronic Myeloproliferative Disorders
Hematology, 2003 AbstractThe Philadelphia chromosome-negative chronic myeloproliferative disorders (CMPD), polycythemia vera (PV), essential thrombocythemia (ET) and chronic idiopathic myelofibrosis (IMF), have overlapping clinical features but exhibit different natural histories and different therapeutic requirements.
Jerry L. Spivak +6 more
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