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Platelet Function, Role in Thrombosis, Inflammation, and Consequences in Chronic Myeloproliferative Disorders [PDF]

open access: yesCells, 2021
Platelets are conventionally defined as playing a vital role in homeostasis and thrombosis. This role has over the years transformed as knowledge regarding platelets has expanded to include inflammation, cancer progression, and metastasis.
Lisa Repsold, Anna Margaretha Joubert
doaj   +3 more sources

A review of current knowledge of myeloproliferative disorders in the horse [PDF]

open access: goldActa Veterinaria Scandinavica, 2021
Myeloid disorders are conditions being characterized by abnormal proliferation and development of myeloid lineage including granulocytes (neutrophils, eosinophils and basophils), monocytes, erythroids, and megakaryocytes precursor cells. Myeloid leukemia,
Katy Satué   +2 more
doaj   +4 more sources

Hereditary myeloproliferative disorders

open access: yesHaematologica, 2010
Hereditary forms of myeloproliferative disorders (MPD) can be divided into two broad categories. First, inherited syndromes that affect a single lineage with Mendelian inheritance, high penetrance and polyclonal hematopoiesis, and second, inherited predisposition to true MPD, characterized by ...
Radek C. Skoda
doaj   +4 more sources

JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders [PDF]

open access: goldF1000Research, 2018
JAK inhibitors have been developed following the discovery of the JAK2V617F in 2005 as the driver mutation of the majority of non- BCR-ABL1 myeloproliferative neoplasms (MPNs).
William Vainchenker   +5 more
openalex   +2 more sources

Bone Marrow Fibrosis in Chronic myeloid leukemia (CML) and other Myeloproliferative Disorders Evaluated by Using Special Histochemical Stains for Collagen.

open access: hybridمجلة كلية الطب, 2011
Background: It is still difficult to give a final diagnosis in chronic myeloproliferative disorders (CMPDs) because of the overlap of the common pathological and clinical features of these disorders like bone marrow fibrosis which is considered important
Ali Khalil I. Al-Khafaji   +2 more
doaj   +3 more sources

Eosinophilic Myeloproliferative Disorders [PDF]

open access: yesHematology, 2011
AbstractDespite recent attempts to define and classify patients with marked eosinophilia and features consistent with myeloproliferative disease, areas of controversy remain. These are particularly apparent in situations in which multiple lineages are involved in a clonal process and clinical manifestations are overlapping. Although the introduction of
A. Klion
openaire   +3 more sources

Chorea and Cognitive Impairment in JAK2V617F-Positive Myeloproliferative Disorders: A Case Report and Literature Review [PDF]

open access: yesMedicina, 2023
Chorea is a hyperkinetic movement disorder, accompanied by dystonia, myoclonus, tics, stereotypies, and tremors. It is characterized by excessive, purposeless movements that are distressing, irregularly timed, and randomly distributed.
Ioana Butnariu   +7 more
doaj   +2 more sources

Pulmonary hypertension in patients with chronic myeloproliferative disorders. [PDF]

open access: yesEur Respir Rev, 2015
Pulmonary hypertension (PH) is a major complication of several haematological disorders. Chronic myeloproliferative diseases (CMPDs) associated with pulmonary hypertension have been included in group five of the clinical classification for pulmonary ...
Adir Y, Elia D, Harari S.
europepmc   +2 more sources

Myeloproliferative Disorders

open access: yesAnnals of Surgery, 1975
Forty-three operative procedures were performed on a population of 250 patients with myeloproliferative disorders, including polycythemia vera, myeloid metaplasia (MM) and chronic myelogenous leukemia (CML). The overall operative mortality was approximately 7% and the incidence of excessive bleeding which could be related to coagulopathy was 5%. Twenty-
S. Schwartz
openaire   +4 more sources

Increased reactive oxygen species production and p47phox phosphorylation in neutrophils from myeloproliferative disorders patients with JAK2 (V617F) mutation

open access: yesHaematologica, 2013
Myeloproliferative disorders are associated with increased risk of thrombosis and vascular complications. The pathogenesis of these complications is not completely known.
Margarita Hurtado-Nedelec   +8 more
doaj   +2 more sources

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