Results 111 to 120 of about 28,496 (220)
ABSTRACT Background and Aim Deletion and single nucleotide polymorphisms in the BIM gene have been proposed as a potential contributor of intrinsic resistance to imatinib in patients with chronic myeloid leukemia (CML). Individual studies, particularly in East Asian population, have reported higher frequency of these gene variants and have suggested ...
Abhinav Bhattarai +4 more
wiley +1 more source
Chronotherapy in Hematological Malignancies: Evaluating the Rationale and Evidence
ABSTRACT Hematological malignancies remain one of the leading causes of morbidity and mortality despite advances in targeted therapies, immunotherapy, and stem cell transplantation. Emerging evidence indicates that treatment efficacy and toxicity depend not only on the choice of therapy but also on its timing relative to the patient's internal ...
Andrej Belančić +7 more
wiley +1 more source
We report a case of chronic myeloid leukaemia (CML) diagnosed during long‐term alectinib therapy in a patient with ALK‐positive non‐small cell lung cancer, in whom CML was confirmed by the presence of the BCR‐ABL1 fusion gene and concomitant nilotinib with continued alectinib achieved a rapid hematologic response without significant adverse events ...
Yuki Ikematsu +3 more
wiley +1 more source
Abstract A 5‐year‐old, male neutered, Bengal‐cross cat presented with progressive neurological signs (ataxia and torticollis). Initial haematology, serum biochemistry and electrolytes (including calcium) were unremarkable; however, ammonia was markedly elevated.
Kerry E. Rolph, Tim Scase, Owen Davies
wiley +1 more source
The microenvironment in myeloproliferative neoplasm
Simón Méndez-Ferrer, Claudia Korn
doaj +1 more source
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê +3 more
wiley +1 more source
Improvement of psoriasis with ruxolitinib in a patient with myeloproliferative neoplasm: a therapeutic observation. [PDF]
Gomide LV, Ribeiro AMQ.
europepmc +1 more source

