Results 161 to 170 of about 115,857 (253)

Haematopoietic Cells Deficient for Calreticulin or Expressing Its Oncogenic Variants Maintain Functional Antigen Presentation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Intact antigen presentation in cancer cells is a key prerequisite for endogenous anticancer T cell responses and a starting point for immunotherapy. Calreticulin was postulated as a chaperone and integral part of the peptide‐loading complex of MHC‐I.
Maria Höhrhan, Laura Antonio‐Herrera, Henrique G. Colaço, Anja Wagner, Markus Unterwurzacher, Cecilia Varga, Klaus Kratochwill, Andreas Bergthaler, Robert Kralovics   +8 more
wiley   +1 more source

Genomic Medicine Sweden: Advancing precision medicine at the national level

Journal of Internal Medicine, Volume 300, Issue 4, Page 397-419, October 2026.
Abstract High‐throughput sequencing has transformed clinical diagnostics of rare diseases (RD), cancer and infectious diseases by enabling the identification of disease‐causing genetic alterations and facilitating individualised treatment and care.
Anders Edsjö, Anna Lindstrand, Panagiotis Baliakas, David Gisselsson, Paula Mölling, Mia Wadelius, Åsa Johansson, Hannes Olauson, Hans Ehrencrona, Lovisa Lovmar, Christian G. Giske, Henrik Green, Ann Nordgren, Fulya Taylan, Martin Hallbeck, Erika Tång Hallbäck, Anna Green, Markus Heidenblad, Kina Höglund, Anders Jemt, Carl Mårten Lindqvist, Maria Johansson Soller, Magnus Sabel, Colum Walsh, Hartmut Vogt, Craig E. Wheelock, Martin Bergö, Jens Enoksson, Ann Ekberg Jansson, Cecilia Fagerström, Jan Holgersson, Stephanie Anja Juran, Mats G. Karlsson, Frida Lundmark, Eva Tiensuu Janson, Andreas Muranyi Scheutz, Malin Sund, Päivi Östling, Sofia Gruvberger‐Saal, Marene Landström, Malin Melin, Lars Palmqvist, Richard Palmqvist, Bianca Stenmark, Anna Wedell, Malin Karnå, Katarina Nyström, Tobias Strid, Per Sikora, Maria Johansson, Therese Fagerqvist, Mirja Carlsson Möller, Oskar Frisell, Mats Ulfendahl, Mikaela Friedman, Lucia Cavelier, Valtteri Wirta, Thoas Fioretos, Richard Rosenquist   +58 more
wiley   +1 more source

Epigenetic Rewiring and Context-Dependent Therapeutic Vulnerabilities in Myeloproliferative Neoplasms. [PDF]

Hematol Oncol
Abdelgawwad El-Sehrawy AAM, Al-Khreisat MJ, Kubaev A, Rajapov A, Ismael SH, Alhasso B, Kaur I, Bainsal N.   +7 more
europepmc   +1 more source

Liver and Spleen Stiffness as Non‐Invasive Tools Assessing Liver Congestion in Patients With Budd‐Chiari Syndrome

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background and Aims Assessing liver congestion and portal hypertension (PHT) in Budd–Chiari syndrome (BCS) remains challenging. We evaluated liver and spleen stiffness measurements (LSM, SSM) obtained by transient elastography as non‐invasive tools for identifying clinically meaningful liver congestion in BCS.
Andreea Fodor, Marcos A. Thompson, Oana Nicoara‐Farcau, Ernesto Belmonte, Ángeles Garcia‐Criado, Anna Darnell, Valeria Pérez‐Campuzano, Pamela Vizcarra, Isabel Requejo, Ángeles Falga, Marina Veléz, Irene Fernandez, Adriana Sueiras, Sonia Torres, Jakub Gazda, Anna Baiges, Sarah Shalaby, Asunción Ojeda, Diego San Martin, Bogdan Procopet, Virginia Hernández‐Gea, Fanny Turon, Juan Carlos García‐Pagan   +22 more
wiley   +1 more source

Are Myeloproliferative Neoplasms-Unclassifiable Really Unclassifiable? [PDF]

EJHaem
Barosi G, Rosti V, Gale RP.
europepmc   +1 more source

Clinical management of clonal hematopoiesis

Cancer, Volume 132, Issue 18, 15 September 2026.
ABSTRACT Clonal hematopoiesis, particularly clonal hematopoiesis of indeterminate potential and clonal cytopenia of undetermined significance, is an age‐related premalignant condition characterized by the expansion of hematopoietic clones carrying somatic mutations.
Kelly S. Chien, Guillermo Garcia‐Manero   +1 more
wiley   +1 more source

Immunotherapeutic targeting of calreticulin mutant myeloproliferative neoplasms. [PDF]

Leukemia
Hertz C, Spyrou N, Hoffman R, Cimen Bozkus C, Bhardwaj N, Tremblay D, Kremyanskaya M, Mascarenhas J.   +7 more
europepmc   +1 more source

Ophthalmological and epidemiological profiles of Brazilian patients with philadelphia-negative Myeloproliferative neoplasms. [PDF]

Hematol Transfus Cell Ther
Piloni-Parreira R, Barbosa MS, Neves LL, Santana HL, Rodrigues JMRDS, Tavares RS, Isaac DLC, Pereira de Ávila M.   +7 more
europepmc   +1 more source

Increased glioblastoma risk in patients with myeloproliferative neoplasms and myelodysplastic syndromes. [PDF]

Clin Exp Med
Zhou H, Jin S, Huang L, Liu W.
europepmc   +1 more source

Genomic characterization of spleens in patients with myelofibrosis

Haematologica, 2018
Eran Zimran, Joseph Tripodi, Raajit Rampal, Franck Rappoport, Sharon Zirkiev, Ronald Hoffman, Vesna Najfeld   +6 more
doaj   +1 more source