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Genetics of the myeloproliferative neoplasms
Current Opinion in Hematology, 2011Since the discovery of the JAK2V617F mutation in 2005, an increasing number of somatic and germline genetic events responsible for myeloproliferative neoplasm (MPN) pathogenesis have been uncovered. The purpose of this review is to outline the most recent discoveries of the genetic alterations found in patients with MPNs.In addition to the JAK2V617F ...
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Cytogenetics of Myeloproliferative Neoplasms
2011The introduction of JAK2 mutation testing has changed dramatically the diagnostic algorithms for myeloproliferative neoplasms (MPNs) but there is still a place for conventional cytogenetic analysis in the initial work-up of MPN cases, particularly as this group of myeloid disorders has been expanded to include chronic eosinophilic leukaemia and myeloid
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Myeloproliferative and Myelodysplastic/Myeloproliferative Neoplasms
2011Myeloproliferative syndromes (MPS) are characterized by clonal proliferation patterns of hematological precursor cells with a tendency to develop acute leukemia. Cytopenias typically seen in myelodysplastic syndrome (MDS) are uncommon, as are dysplastic morphological features.
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Cardiovascular Disease in Myeloproliferative Neoplasms
JACC: CardioOncology, 2022Gabriela Hobbs, Peter Libby, Orly Leiva
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