Results 81 to 90 of about 49,427 (236)

Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms [PDF]

, 2017
Baobing Zhao, Yang Mei, Lan Cao, Jingxin Zhang, Ronen Sumagin, Jing Yang, Juehua Gao, Matthew J. Schipma, Yanfeng Wang, Chelsea Thorsheim, Liang Zhao, Timothy J. Stalker, Brady L. Stein, Qiang Wen, John D. Crispino, Charles S. Abrams, Peng Ji   +16 more
openalex   +1 more source

Targeted cancer exome sequencing reveals recurrent mutations in myeloproliferative neoplasms [PDF]

, 2014
With the intent of dissecting the molecular complexity of Philadelphia-negative myeloproliferative neoplasms (MPN), we designed a target enrichment panel to explore, using next-generation sequencing (NGS), the mutational status of an extensive list of 2 ...
A. M. Vannucchi, A. Pancrazzi, ARTUSI, VALENTINA, ARTUSO, LUCIA, BERNARDIS, ISABELLA, BIANCHI, Elisa, C. Bogani, C. Mannarelli, E. Roncaglia, F. Biamonte, FERRARI, Sergio, G. Rotunno, L. Pieri, MALAGOLI TAGLIAZUCCHI, GUIDANTONIO, MANFREDINI, Rossella, P. Guglielmelli, T. Fanelli, TAGLIAFICO, Enrico, TENEDINI, Elena   +18 more
core   +1 more source

Autoimmunity and the risk of myeloproliferative neoplasms

Haematologica, 2010
The causes of myeloproliferative neoplasm (MPN) are unknown. We conducted a large population-based study including 11,039 myeloproliferative neoplasm patients and 43,550 matched controls with the aim of assessing the associations between a personal ...
Sigurdur Y. Kristinsson, Ola Landgren, Jan Samuelsson, Magnus Björkholm, Lynn R. Goldin   +4 more
doaj   +1 more source

Biomolecular and histological features in pediatric essential thrombocythemia: adequacy of who diagnostic criteria [PDF]

, 2017
Myeloproliferative neoplasms (MPN), Essential Thrombocythemia (ET), Polycythemia Vera (PV) and primary myelofibrosis (PMF), are clonal disorders of the hematopoietic stem cell.
Bertozzi, Irene
core   +1 more source

KITD816V+ systemic mastocytosis associated with KITD816V+ acute erythroid leukaemia: first case report with molecular evidence for same progenitor cell derivation [PDF]

, 2009
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
H-P Horny, K K Reichard, K Sotlar, M K Foucar, S A McClintock-Treep   +4 more
core   +1 more source

P198 | BONE MARROW FIBROSIS IN POLYCYTHEMIA VERA AND ESSENTIAL THROMBOCYTHEMIA: CLINICAL, MOLECULAR AND PROGNOSTIC IMPLICATIONS

Haematologica
Background Mild BM fibrosis (MF-1) can be identified in up to 20% of patients (pts) with polycythemia vera (PV) and essential thrombocytemia (ET), and may play a role –albeit still poorly defined–in pathophysiology, clinical presentation ad long-term ...
G. Coltro, G. Borgi, V. Boldrini, F. Gesullo, F. Violi, M. Balliu, P. Guglielmelli   +6 more
doaj  

Twenty-five years of epidemiological recording on myeloid malignancies: data from the specialized registry of hematologic malignancies of Côte d’Or (Burgundy, France)

Haematologica, 2011
Background Epidemiological data on myeloid malignancies are very rare in the literature due to a lack of registration by cancer registries until 2000.
Marc Maynadié, François Girodon, Ines Manivet-Janoray, Morgane Mounier, Francine Mugneret, François Bailly, Bernardine Favre, Denis Caillot, Tony Petrella, Michel Flesch, Paule-Marie Carli   +10 more
doaj   +1 more source

C030 | GENOTYPE-PHENOTYPE CORRELATES AND OUTCOMES OF EXTRAMEDULLARY ACUTE MYELOID LEUKEMIA

Haematologica
Background: Genomic abnormalities associated with extramedullary (EM) acute myeloid leukemia (eAML) and their impact on clinical outcomes are not well understood since previous studies were limited to small case series with controversial results.
G.G. Loscocco, F. Mannelli, M. Piccini, B. Scappini, F. Crupi, G. Ciolli, L. Fasano, G. Rotunno, F. Pancani, C. Maccari, L. Signori, P. Guglielmelli, A.M. Vannucchi   +12 more
doaj  

JAK2 p.V617F detection and allele burden measurement in peripheral blood and bone marrow aspirates in patients with myeloproliferative neoplasms [PDF]

, 2013
Koichi Takahashi, Keyur P. Patel, Hagop M. Kantarjian, Rajyalakshmi Luthra, Sherry Pierce, Jörge E. Cortes, Srđan Verstovšek   +6 more
openalex   +1 more source

Clinical Discernment, Bone Marrow, and Molecular Diagnostics Are Equally Important to Solve the Phenotypic Mimicry among Subtypes of Myeloproliferative Neoplasms [PDF]

, 2021
Susann Schulze, Nadia Jaekel, Christin Le Hoa Naumann, Anja Haak, Marcus Bauer, Claudia Wickenhauser, Haifa Kathrin Al‐Ali   +6 more
openalex   +1 more source