Hematopoietic Effects of Angelica gigas Nakai Extract on Cyclophosphamide-Induced Myelosuppression
Plants, 2022 Myelosuppression is a major adverse effect of chemotherapy. With the increasing number of cancer patients worldwide, there is a growing interest in therapeutic approaches that reduce the adverse effects of chemotherapy.
Mincheol Kang +5 more
doaj +2 more sources
Association between Prognostic Nutritional Index and myelosuppression in gastric cancer patients undergoing chemotherapy: a retrospective cohort study [PDF]
Frontiers in NutritionObjectiveTo investigate the association between Prognostic Nutritional Index (PNI) and chemotherapy-induced myelosuppression in gastric cancer patients.MethodsThis retrospective cohort study analyzed 562 gastric cancer patients receiving chemotherapy at ...
Kexia Chen +6 more
doaj +2 more sources
Frontiers in Pharmacology, 2021 The aim of this study was to investigate the correlation between genetic polymorphisms of azathioprine-metabolizing enzymes and adverse reactions of myelosuppression. To this end, a retrospective analysis was performed on 1,419 Chinese patients involving
Zhao-Yang Chen +16 more
doaj +2 more sources
Risk factors analysis and nomogram development for myelosuppression in diffuse large B-cell lymphoma patients undergoing first-line chemotherapy: a dual-centre retrospective cohort study [PDF]
PeerJObjective The primary objective of this research was to examine the characteristics of myelosuppression following first-line chemotherapy in patients suffering from diffuse large B-cell lymphoma (DLBCL).
Xuexing Wang +6 more
doaj +3 more sources
Linezolid-Induced Myelosuppression
Annals of Internal Medicine: Clinical CasesLinezolid is an antibiotic effective against resistant gram-positive bacteria. While side effects are typically mild, myelosuppression can occur, with pancytopenia being a rare but serious condition.
Kristiana Jordan, Kristen D. Kelley
doaj +2 more sources
Frontiers in Oncology, 2021 Chemotherapy-induced damage of hematopoietic stem and progenitor cells (HPSCs) often results in myelosuppression that adversely affects patient health and quality of life. Currently, chemotherapy-induced myelosuppression is managed with chemotherapy dose
Gary H. Lyman +3 more
doaj +1 more source
Cancer Medicine, 2023 Purpose Whether the addition of tislelizumab to gemcitabine and cisplatin (GC) chemotherapy increases the incidence of myelosuppression has not been well established.
Zhimin Gao +8 more
doaj +1 more source
Overcoming myelosuppression due to synthetic lethal toxicity for FLT3-targeted acute myeloid leukemia therapy. [PDF]
, 2014 Activating mutations in FLT3 confer poor prognosis for individuals with acute myeloid leukemia (AML). Clinically active investigational FLT3 inhibitors can achieve complete remissions but their utility has been hampered by acquired resistance and ...
He, Bai-Liang +9 more
core +5 more sources
A preliminary study on effect of carbon ion radiotherapy on bone marrow suppression
Radiation Medicine and Protection, 2022 Objective: To explore the effect of carbon ion radiotherapy (CIRT) on the bone marrow adjacent to or within the treatment fields, and to observe the bone marrow toxicities after CIRT alone.
Ying Qi +9 more
doaj +1 more source
Mechanism-based model characterizing bidirectional interaction between PEGylated liposomal CKD-602 (S-CKD602) and monocytes in cancer patients [PDF]
, 2012 S-CKD602 is a PEGylated liposomal formulation of CKD-602, a potent topoisomerase I inhibitor. The objective of this study was to characterize the bidirectional pharmacokinetic-pharmacodynamic (PK-PD) interaction between S-CKD602 and monocytes.
Bang YJ +12 more
core +2 more sources