Results 21 to 30 of about 36,039 (270)

Human Cytomegalovirus Infection Suppresses CD34⁺ Progenitor Cell Engraftment in Humanized Mice

Microorganisms, 2020
Human cytomegalovirus (HCMV) infection is a serious complication in hematopoietic stem cell transplant (HSCT) recipients due to virus-induced myelosuppression and impairment of stem cell engraftment.
Lindsey B. Crawford, Rebecca Tempel, Daniel N. Streblow, Andrew D. Yurochko, Felicia D. Goodrum, Jay A. Nelson, Patrizia Caposio   +6 more
doaj   +1 more source

A preliminary study on effect of carbon ion radiotherapy on bone marrow suppression

Radiation Medicine and Protection, 2022
Objective: To explore the effect of carbon ion radiotherapy (CIRT) on the bone marrow adjacent to or within the treatment fields, and to observe the bone marrow toxicities after CIRT alone.
Ying Qi, Xin Pan, Caixia Lyu, Wanguo Li, Huixiang Lu, Sha Li, Yanshan Zhang, Xiaoli Lu, Dongji Chen, Yee-Min Jen   +9 more
doaj   +1 more source

Multivariate analysis of febrile neutropenia occurrence in patients with non-Hodgkin lymphoma: data from the INC-EU Prospective Observational European Neutropenia Study [PDF]

, 2008
Summary Myelosuppression, particularly febrile neutropenia (FN), are serious dose-limiting toxicities that occur frequently during the first cycle of chemotherapy.
Impact of Neutropenia in Chemotherapy-European Study Group (INC-, Paridaens, R, Szucs, Thomas D., Matthias Schwenkglenks, Pettengell, R, Bosly, André, Schwenkglenks, Matthias, Jackisch, C, Jackisch, Christian, Thomas D. Szucs, Manuel Constenla, Constenla, Manuel, Szucs, T D, Schwenkglenks, M, André Bosly, Leonard, Robert, Paridaens, Robert, Christian Jackisch, Robert Leonard, Pettengell, Ruth, Ruth Pettengell, Robert Paridaens, Bosly, A, Impact of Neutropenia in Chemotherapy-European Study Group,, Szucs, TD, Leonard, R, Constenla, M   +26 more
core   +1 more source

Dosage Strategy of Linezolid According to the Trough Concentration Target and Renal Function in Chinese Critically Ill Patients

Frontiers in Pharmacology, 2022
Background: Linezolid is associated with myelosuppression, which may cause failure in optimally treating bacterial infections. The study aimed to define the pharmacokinetic/toxicodynamic (PK/TD) threshold for critically ill patients and to identify a ...
Fan Wu, Xiao-Shan Zhang, Ying Dai, Zi-Ye Zhou, Chun-Hong Zhang, Lu Han, Fang-Min Xu, Ye-Xuan Wang, Da-Wei Shi, Guan-Yang Lin, Xu-Ben Yu, Fang Chen   +11 more
doaj   +1 more source

Myeloprotective activity of crude methanolic leaf extract of Cassia occidentalis in cyclophosphamide-induced bone marrow suppression in Wistar rats

Advanced Biomedical Research, 2015
Background: Myelosuppression is the most common dose-limiting side effect of chemotherapy. Cassia occidentalis plays a vital role in preventing health disorders, but its hematological effects have not been documented much.
Emeka E Neboh, Silas A Ufelle
doaj   +1 more source

Genotype-based Treatment With Thiopurine Reduces Incidence of Myelosuppression in Patients With Inflammatory Bowel Diseases

, 2020
BACKGROUND & AIMS: Thiopurine-related myelosuppression (most frequently leukopenia) interferes with thiopurine therapy for patients with inflammatory bowel diseases (IBD).
정성애, 문창모
core   +2 more sources

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Modulation of Animal and Human Hematopoiesis by β-Glucans: A Review

Molecules, 2011
β-Glucans are cell wall constituents of bacteria, yeast, fungi, and plants. They are not expressed in mammalian cells, but they are recognized by mammalian cells as pathogen-associated molecular patterns by pattern recognition receptors and thus act as ...
Milan Pospíšil, Michal Hofer
doaj   +1 more source

Activation of Nrf2-ARE signaling mitigates cyclophosphamide-induced myelosuppression

, 2016
Myelosuppression is the most common dose-limiting adverse effect of chemotherapies. In the present study, we investigated the involvement of nuclear erythroid 2-related factor 2 (Nrf2) in cyclophosphamide-induced myelosuppression in mice, and evaluated ...
He, Liu, Yu, Siwang, Que, Linling, Cao, Baoshan, Yu, Chenshu, Yin, Wencheng, Ma, Liwen   +6 more
core   +1 more source

Contribution of the local RAS to hematopoietic function: a novel therapeutic target

Frontiers in Endocrinology, 2013
The renin angiotensin system (RAS) has long been a known endocrine system that is involved in regulation of blood pressure and fluid balance. Over the last 2 decades, evidence has accrued that shows that there are local RAS that can affect cellular ...
Kathleen E. Rodgers, Gere S. diZerega, Gere S. diZerega   +2 more
doaj   +1 more source