Results 51 to 60 of about 60,444 (298)

Astragaloside IV and Saponins of Rhizoma Polygonati Cure Cyclophosphamide-Induced Myelosuppression in Lung Adenocarcinoma via Down-Regulating miR-142-3p

Frontiers in Oncology, 2021
Our previous study revealed that Shuanghuang Shengbai granule could cure the myelosuppression induced by cyclophosphamide (CTX) in lung cancer. However, its hematopoietic effects and molecular mechanisms remain not fully understood. Therefore, this study
Xian Gu, Ling-yu Zhu, Zhen-ye Xu, Ke-ping Shen   +3 more
doaj   +1 more source

Neoadjuvant endocrine therapy for luminal breast cancer treatment: a first-choice alternative in times of crisis such as the COVID-19 pandemic [PDF]

, 2020
The epidemiological emergency caused by CoV-2 (COVID-19) has changed priorities in breast cancer management. In those places where the pandemic has had the greatest effect, it is of paramount importance for most patients to be at home, reducing or ...
Martí, Covadonga, Sánchez-Méndez, José I.   +1 more
core   +1 more source

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease

Journal of the American Medical Association (JAMA), 2019
Importance Use of thiopurines may be limited by myelosuppression. TPMT pharmacogenetic testing identifies only 25% of at-risk patients of European ancestry.
G. Walker, James W. Harrison, G. Heap, M. Voskuil, V. Andersen, C. Anderson, A. Ananthakrishnan, J. Barrett, L. Beaugerie, C. Bewshea, A. Cole, Fraser Cummings, M. Daly, P. Ellul, R. Fedorak, E. Festen, T. Florin, D. Gaya, J. Halfvarson, A. Hart, N. Heerasing, P. Hendy, P. Irving, Samuel E. Jones, J. Koskela, J. Lindsay, J. Mansfield, D. McGovern, M. Parkes, R. Pollok, S. Ramakrishnan, D. Rampton, M. Rivas, R. Russell, M. Schultz, S. Sebastian, P. Seksik, Abhey Singh, K. So, H. Sokol, K. Subramaniam, A. Todd, V. Annese, R. Weersma, R. Xavier, R. Ward, M. Weedon, J. Goodhand, N. Kennedy, Tariq Ahmad   +49 more
semanticscholar   +1 more source

Targeted radiotherapy of neuroblastoma: future directions [PDF]

, 2017
No abstract ...
Gaze, Mark N., Mairs, Robert, Nile, Donna L., Rae, Colin, Tesson, Mathias   +4 more
core   +2 more sources

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Case report: NUDT15 polymorphism and severe azathioprine-induced myelosuppression in a young Chinese female with systematic lupus erythematosus: a case analysis and literature review

Frontiers in Pharmacology, 2023
Azathioprine is clinically used as an immunosuppressant for treating autoimmune diseases. However it has narrow therapeutic indices due to frequent myelosuppression.
Juan Gu, Yupei Lin, Yuhe Wang
doaj   +1 more source

Chemotherapy induced myelosuppression

East African Medical Journal, 2007
To evaluate chemotherapy induced myelosuppression, its management and outcome.Retrospective analysis of patients aged 13 years and above.Hurlingham Oncology Clinic and the Nairobi Hospital during the period of June 1998 to June 2003.Two hundred and two solid tumour and lymphoma patients treated with pulsed chemotherapy at Hurlingham Oncology Clinic and
Othieno-Abinya, N. A., Waweru, A., Nyabola, L. O.   +2 more
openaire   +4 more sources

The impact of myelosuppression on quality of life of patients treated with chemotherapy

Future Oncology
Side effects from chemotherapy-induced myelosuppression can negatively affect patients' quality of life (QoL). Neutropenia increases infection risk, and anemia frequently results in debilitating fatigue.
Jeffrey Crawford, D. Herndon, Katerina Gmitter, Jared Weiss   +3 more
semanticscholar   +1 more source

Thiopurine methyltransferase polymorphisms in children with acute lymphoblastic leukemia

Indian Journal of Medical and Paediatric Oncology, 2014
Introduction: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. 6-mercaptopurine (6-MP) and methotrexate are backbone drugs for maintenance phase of treatment. Purine Analogs 6-MP/6-thioguanine/azathiopurine are metabolized to
Vijay Gandhi Linga, Dorra Babu Patchva, Krishna Mohan Mallavarapu Venkata Tulasi, Krishnamani Iyer Kalpathi, Ashok Pillai, Sadashivudu Gundeti, Senthil J Rajappa, Raghunadharao Digumarti   +7 more
doaj   +1 more source

Evaluating the Effects of Prostate Radiotherapy Intensified with Pelvic Nodal Radiotherapy and Androgen Deprivation Therapy on Myelosuppression: Single-Institution Experience

Current Oncology
Background: Prostate cancer (PCa) management commonly involves the utilization of prostate radiotherapy (PRT), pelvic nodal radiotherapy (PNRT), and androgen deprivation therapy (ADT). However, the potential association of these treatment modalities with
Yousef Katib, Steven Tisseverasinghe, Ian J. Gerard, Benjamin Royal-Preyra, Ahmad Chaddad, Tania Sasson, Boris Bahoric, Federico Roncarolo, Tamim Niazi   +8 more
doaj   +1 more source