Results 81 to 90 of about 60,444 (298)

Rare tuberculosis in recipients of allogeneic hematopoietic stem cell transplantation successfully treated with contezolid–a typical case report and literature review

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundTuberculosis (TB) is a rare but potentially devastating complication in hematopoietic stem cell transplantation (HSCT) recipients. Myelosuppression-related antibiotics should be used cautiously in patients with hematological malignancies ...
Junhong Li, Junhong Li, Zhaoxian Yu, Zhaoxian Yu, Yingyi Jiang, Yingyi Jiang, Suihua Lao, Suihua Lao, Dexian Li, Dexian Li   +9 more
doaj   +1 more source

Rituximab in combination with high-dose methylprednisolone for the treatment of chronic lymphocytic leukemia. [PDF]

, 2009
We observed that high-dose methylprednisolone (HDMP) and rituximab was well tolerated and had promising activity when used in combination to treat patients with fludarabine-refractory chronic lymphocytic leukemia (CLL).
Bole, J, Castro, JE, Jain, S, James, DF, Kipps, TJ, Rassenti, L, Sandoval-Sus, JD   +6 more
core  

Rapid Genome and Exome Sequencing in Inpatients: Clinical Impact at a Tertiary Academic Medical Center

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The objective of this study is to describe outcomes of rapid exome (rES) and rapid genome sequencing (rGS) in an inpatient setting. This is a retrospective cohort of inpatients with rES or rGS during their hospitalization between April 2016 and November 2023.
Cecilia M. Kessler, Bryce A. Schuler, Elizabeth A. Jasper, Janet Talbert, Laura Duncan, Mackenzie Mosera   +5 more
wiley   +1 more source

Study on Hemostimulating Properties of Granulocyte-Macrophage Colony Stimulating Factor

Биопрепараты: Профилактика, диагностика, лечение, 2020
The hemostimulating properties of granulocyte-macrophage colony-stimulating factor (GM-CSF) make possible its clinical use in alleviating side effects of anti-cancer radio- and chemotherapy, in bone marrow transplantation, and in the treatment of some ...
G. G. Shimina, A. V. Bateneva, S. G. Gamaley, T. I. Esina, T. G. Tereshchenko, E. D. Danilenko   +5 more
doaj   +1 more source

Therapeutic Effects of Plant Extracts of Anoectochilus roxburghii on Side Effects of Chemotherapy in BALB/c Breast Cancer Mice

Plants, 2023
Breast cancer is the most common cancer in women, and chemotherapy is an effective treatment. However, chemotherapy often causes adverse side effects such as cardiotoxicity, myelosuppression, immunodeficiency, and osteoporosis.
Chi-Feng Cheng, Chen-Wen Lu, Wen-Jhen Wu, Li-Yu Su, Thi Kim Ngan Nguyen, Szu-Chuan Shen, Chia-Ying Lien, Wu-Chang Chuang, Ming-Chung Lee, Chung-Hsin Wu   +9 more
doaj   +1 more source

Immunomagnetic t-lymphocyte depletion (ITLD) of rat bone marrow using OX-19 monoclonal antibody [PDF]

, 1989
Graft versus host disease (GVHD) may be abrogated and host survival prolonged by in vitro depletion of T lymphocytes from bone marrow (BM) prior to allotransplantation. Using a mouse anti-rat pan T-lymphocyte monoclonal antibody (0×19) bound to monosized,
A. Pascualone, A.L. Hoffman, B.F. Banner, Barclay A, Berenson R J, Beschorner W E, Bril H, D.G. Sheahan, D.V. Cramer, Dallman M J, Elkins W L, Farnsworth A, Filipovich A H, Kvalheim G, L. Makowka, Lubaroff D M, Martin P J, Monchik G J, Oaks M K, P. Rettinger, Prentice H G, Reisner Y, Rodt H, Slavin R E, T.E. Starzl, Thtschka P J, Tsoi M-S, Van Bekkum D W, Vartdal F, Waldman H, X. Cai   +30 more
core   +1 more source

Atypical cause of prolonged myelosuppression

BMJ Case Reports, 2009
We present the case of a 57-year-old male with poor prognosis (trisomy 21 and monosomy 7) acute myeloid leukaemia (AML) who presented with rigors and fever during cytogenetic remission.Peripheral and central line blood cultures were positive forMycobacterium chelonaeand he commenced empiric treatment with meropenem, amikacin, clarithromycin and ...
Andrew, Smyth, Barry, Macdonagh, Helen, Tuite, Catherine, Fleming, Michael, O'Dwyer   +4 more
openaire   +3 more sources

A Doxorubicin‐Loaded Liposomes Baghdadite System for Localized Osteosarcoma Therapy and Bone Regeneration

Advanced NanoBiomed Research, EarlyView.
This study presents a multifunctional Baghdadite ceramic implant integrating doxorubicin‐loaded liposomes via ion‐assisted plasma polymer coating for localized osteosarcoma therapy. The platform enables drug retention, sustained release, tumor cell inhibition, osteoconductivity, and antibacterial activity, offering a mechanically robust strategy for ...
Sally Kortam, Zufu Lu, Iman Roohani, Ghazal Shineh, Leila Mamizadeh Janghour, Huu Nguyen Ngoc, Pooria Lesani, Behnam Akhavan, Hala Zreiqat   +8 more
wiley   +1 more source

Human Cytomegalovirus miRNAs Regulate TGF-β to Mediate Myelosuppression while Maintaining Viral Latency in CD34+ Hematopoietic Progenitor Cells.

Cell Host and Microbe, 2019
Infection with human cytomegalovirus (HCMV) remains a significant cause of morbidity and mortality following hematopoietic stem cell transplant (HSCT) because of various hematologic problems, including myelosuppression. Here, we demonstrate that latently
Meaghan H. Hancock, Lindsey B. Crawford, Andrew H. Pham, Jennifer Mitchell, Hillary M. Struthers, A. Yurochko, Patrizia Caposio, J. Nelson   +7 more
semanticscholar   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source