Results 11 to 20 of about 8,496 (180)

scRNA-Seq Reveals New Enteric Nervous System Roles for GDNF, NRTN, and TBX3Summary

Cellular and Molecular Gastroenterology and Hepatology, 2021
Background and Aims: Bowel function requires coordinated activity of diverse enteric neuron subtypes. Our aim was to define gene expression in these neuron subtypes to facilitate development of novel therapeutic approaches to treat devastating enteric ...
Christina M. Wright, Sabine Schneider, Kristen M. Smith-Edwards, Fernanda Mafra, Anita J.L. Leembruggen, Michael V. Gonzalez, Deepika R. Kothakapa, Jessica B. Anderson, Beth A. Maguire, Tao Gao, Tricia A. Missall, Marthe J. Howard, Joel C. Bornstein, Brian M. Davis, Robert O. Heuckeroth   +14 more
doaj   +1 more source

Homeoprotein OTX1 and OTX2 involvement in rat myenteric neuron adaptation after DNBS-induced colitis [PDF]

PeerJ, 2020
Background Inflammatory bowel diseases are associated with remodeling of neuronal circuitries within the enteric nervous system, occurring also at sites distant from the acute site of inflammation and underlying disturbed intestinal functions ...
Michela Bistoletti, Giovanni Micheloni, Nicolò Baranzini, Annalisa Bosi, Andrea Conti, Viviana Filpa, Cristina Pirrone, Giorgia Millefanti, Elisabetta Moro, Annalisa Grimaldi, Roberto Valli, Andreina Baj, Francesca Crema, Cristina Giaroni, Giovanni Porta   +14 more
doaj   +2 more sources

Neurochemical phenotypes of myenteric neurons in the rhesus monkey [PDF]

Journal of Comparative Neurology, 2011
AbstractUnderstanding the neurochemical composition of the enteric nervous system (ENS) is critical for elucidating neurological function in the gastrointestinal (GI) tract in health and disease. Despite their status as the closest models of human neurological systems, relatively little is known about enteric neurochemistry in nonhuman primates.
Ali Reza, Noorian, Georgia M, Taylor, Dana M, Annerino, James G, Greene   +3 more
openaire   +2 more sources

Expression of substance P, vasoactive intestinal peptide and galanin in cultured myenteric neurons from the ovine abomasums

Veterinární Medicína, 2009
Enteric neurons are able to alter their neurotransmitter content during adaptation to new artificial conditions. The aim of the present study was to investigate changes in vasoactive intestinal peptide (VIP), substance P (SP) and galanin expression ...
M.B. Arciszewski, S. Barabasz, J. Calka
doaj   +1 more source

Location, distribution, and quantification of myenteric plexus neurons of the jejunum of quails fed with different levels of commercial Macleaya cordata extract

Ciência Rural, 2021
: Coturniculture has been promising, progressing from a subsistence to a technical activity due to its quick production, low breeding investment, and rapid economic return.
Patrícia Franco Gonçalves Previato do Amaral, Wesley Alves Trindade, Paula Montanhini Favetta, Edson Gerônimo, Isabel Cristina da Silva, Grazielli de Fatima Serenini, Gustavo Costardi Palin, Tatiana Kaori Urano, Jean Marcos de Morais Oliveira, Lucas de Almeida Reati, Jaciele Caroline Pereira Dias, Luciana Kazue Otutumi, Andréia Assunção Soares, Ricardo de Melo Germano   +13 more
doaj   +1 more source

Morphology and Chemical Coding of Rat Duodenal Enteric Neurons following Prenatal Exposure to Fumonisins

Animals, 2022
Fumonisins (FBs), including fumonisin B1 and B2 produced by the fungus Fusarium verticillioides, are widespread mycotoxins contaminating crop plants as well as processed food.
Katarzyna Kras, Halyna Rudyk, Siemowit Muszyński, Ewa Tomaszewska, Piotr Dobrowolski, Volodymyr Kushnir, Viktor Muzyka, Oksana Brezvyn, Marcin B. Arciszewski, Ihor Kotsyumbas   +9 more
doaj   +1 more source

Antagonism of ionotropic glutamate receptors attenuates chemical ischemia-induced injury in rat primary cultured myenteric ganglia.

PLoS ONE, 2014
Alterations of the enteric glutamatergic transmission may underlay changes in the function of myenteric neurons following intestinal ischemia and reperfusion (I/R) contributing to impairment of gastrointestinal motility occurring in these pathological ...
Elisa Carpanese, Paola Moretto, Viviana Filpa, Silvia Marchet, Elisabetta Moro, Francesca Crema, Gianmario Frigo, Cristina Giaroni   +7 more
doaj   +1 more source

Three distinct classes of myenteric ganglia in mice and humans: insights from quantitative analyses [PDF]

PeerJ
Background The myenteric plexus primarily consists of the myenteric ganglia, which include enteric neurons, synaptic neuropils, and glial cells. Abnormal myenteric plexus formation can result in gastrointestinal disorders.
Luyao Wu, Lei Xiang, Yingjian Chen, Handan Mao, Xinyao Meng, Jing Wang, Honglin Li, Xuyong Chen, Jiexiong Feng, Jun Xiao   +9 more
doaj   +2 more sources

Cholera Toxin Induces Sustained Hyperexcitability in Myenteric, but Not Submucosal, AH Neurons in Guinea Pig Jejunum

Frontiers in Physiology, 2017
Background and Aims: Cholera toxin (CT)-induced hypersecretion requires activation of secretomotor pathways in the enteric nervous system (ENS). AH neurons, which have been identified as a population of intrinsic sensory neurons (ISNs), are a source of ...
Joel C. Bornstein, Katerina Koussoulas, Rachel M. Gwynne, Jaime P. P. Foong   +3 more
doaj   +1 more source

Types of Neurons in the Human Colonic Myenteric Plexus Identified by Multilayer Immunohistochemical CodingSummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background and Aims: Gut functions including motility, secretion, and blood flow are largely controlled by the enteric nervous system. Characterizing the different classes of enteric neurons in the human gut is an important step to understand how its ...
Bao Nan Chen, Adam Humenick, Wai Ping Yew, Rochelle A. Peterson, Lukasz Wiklendt, Phil G. Dinning, Nick J. Spencer, David A. Wattchow, Marcello Costa, Simon J.H. Brookes   +9 more
doaj   +1 more source