Results 61 to 70 of about 11,706 (220)

Obstruction of Bowel due to Lesion in the Myenteric Plexus [PDF]

BMJ, 1969
Two patients are described who were found to have a destructive lesion of the myenteric plexus. In one the upper small intestine was involved and the clinical picture was of recurrent pseudo-obstruction; in the other the lesion was in the distal colon and resulted in intractable constipation.
N H, Dyer, A M, Dawson, B F, Smith, I P, Todd   +3 more
openaire   +2 more sources

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, EarlyView.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

Myenteric plexus abnormalities associated with epiphrenic diverticula☆ [PDF]

European Journal of Cardio-Thoracic Surgery, 2009
To (1) categorize histologic esophageal myenteric plexus abnormalities in patients undergoing surgical treatment for epiphrenic diverticulum, and (2) correlate histologic changes with associated esophageal motility disorders and hiatal hernia.From January 1987 to May 2008, 40 patients had surgery for epiphrenic diverticulum.
Thomas W, Rice, John R, Goldblum, Martha M, Yearsley, Steven S, Shay, Scott I, Reznik, Sudish C, Murthy, David P, Mason, Eugene H, Blackstone   +7 more
openaire   +2 more sources

Beta-3 Adrenoceptor Agonism Protects the Enteric Nervous Tissue Against Hyperoxia-Induced Damage

Cells
The beta-3 adrenergic receptor (β3-AR), whose expression is modulated by oxygen levels, was found to play a key role in organ maturation, and its agonism was reported to mitigate hyperoxia-induced large bowel damage by preventing organ hypoplasia ...
Patrizia Nardini, Luca Filippi, Virginia Zizi, Marta Molino, Camilla Fazi, Matteo Chivetti, Alessandro Pini   +6 more
doaj   +1 more source

Feed-Forward Inhibition of CD73 and Upregulation of Adenosine Deaminase Contribute to the Loss of Adenosine Neuromodulation in Postinflammatory Ileitis

Mediators of Inflammation, 2014
Purinergic signalling is remarkably plastic during gastrointestinal inflammation. Thus, selective drugs targeting the “purinome” may be helpful for inflammatory gastrointestinal diseases. The myenteric neuromuscular transmission of healthy individuals is
Cátia Vieira, Maria Teresa Magalhães-Cardoso, Fátima Ferreirinha, Isabel Silva, Ana Sofia Dias, Julie Pelletier, Jean Sévigny, Paulo Correia-de-Sá   +7 more
doaj   +1 more source

Prenatal intestinal obstruction affects the myenteric plexus and causes functional bowel impairment in fetal rat experimental model of intestinal atresia. [PDF]

PLoS ONE, 2013
BACKGROUND: Intestinal atresia is a rare congenital disorder with an incidence of 3/10,000 birth. About one-third of patients have severe intestinal dysfunction after surgical repair. We examined whether prenatal gastrointestinal obstruction might effect
Naziha Khen-Dunlop, Sabine Sarnacki, Anais Victor, Celine Grosos, Sandrine Menard, Rodolphe Soret, Nicolas Goudin, Maud Pousset, Frederique Sauvat, Yann Revillon, Nadine Cerf-Bensussan, Michel Neunlist   +11 more
doaj   +1 more source

Parkinson's disease constipation effect of electroacupuncture at ST25 through colonic motility and enteric neuropathology

Frontiers in Neurology, 2023
BackgroundThe enteric nervous system (ENS) plays a central role in developing Parkinson's disease (PD) constipation, and the regulation of the ENS may be a key component in treating PD constipation.
Li-zhe-xiong Song, Li-zhe-xiong Song, Yuan Li, Yuan Li, Xu Qian, Xu Qian, Na Xu, Na Xu, Zhi Yu, Zhi Yu, Jing-wen Dai, Bin Xu, Bin Xu, Xuan-ming Hu   +13 more
doaj   +1 more source

Evaluating integrative strategies for incorporating phenotypic features in spatial transcriptomics

Journal of Microscopy, EarlyView.
Abstract The key advantage of spatial transcriptomics (ST) technologies lies in the spatial domain: these techniques not only offer an unprecedented opportunity to interrogate intact biological samples in a spatially informed manner, but also set the stage for integration with other imaging‐based modalities.
Levin M Moser, Ahmad Kamal Hamid, Esteban Miglietta, Nodar Gogoberidze, Beth A Cimini   +4 more
wiley   +1 more source

Mechanisms regulating somatostatin release and somatostatin-induced acetylcholine release from the myenteric plexus [PDF]

, 1990
The present studies were performed to characterize the molecular form(s) of somatostatin present in the myenteric plexus and to examine some aspects of the regulatory mechanisms underlying somatostatin release and somatostatin-induced release of ...
Owyang, Chung, Wiley, John, Yuanxu Lu,
core   +1 more source

The ciliary neurotrophic factor induces Stat3 phosphorylation in distinctive cytotypes of organs involved in body metabolism: An immunohistochemical study

Journal of Anatomy, EarlyView.
p‐STAT3‐positive cells in metabolically relevant peripheral organs and tissues from mice administered with recombinant CNTF (0.3 mg/kg). Abstract Administration of ciliary neurotrophic factor (CNTF) reduces food intake and body weight in both humans and experimental animals, where it also ameliorates hyperglycemia, hyperinsulinemia, and dyslipidemia ...
Chiara Galli, Georgia Colleluori, Jessica Perugini, Edoardo Scopini, Ilenia Severi, Gaia Grandin, Antonio Giordano   +6 more
wiley   +1 more source