Results 101 to 110 of about 13,305 (193)

The Effect of 14 Weeks of Endurance Training on MYH7 and MYH7β Gene Expression and Left Ventricular Structural Changes in Male Wistar Rats

Armaghane Danesh Bimonthly Journal, 2019
Background & aim:  MYH7 and MYH7β genes play important roles in cardiac function. Endurance activity, on the other hand, challenges the structure and function of the heart. The aim of the present study was to determine and evaluate the effect of 14 weeks
R Rezaei, M Fathi
doaj  

Prevalence and Phenotypic Expression of Mutations in the MYH7, MYBPC3 and TNNT2 Genes in Families with Hypertrophic Cardiomyopathy in the South of Brazil: A Cross-Sectional Study

Arquivos Brasileiros de Cardiologia
Background: Mutations in sarcomeric genes are found in 60-70% of individuals with familial forms of hypertrophic cardiomyopathy (HCM). However, this estimate refers to northern hemisphere populations. The molecular-genetic profile of HCM has been subject
Beatriz Piva e Mattos, Fernando Luís Scolari, Marco Antonio Rodrigues Torres, Laura Simon, Valéria Centeno de Freitas, Roberto Giugliani, Úrsula Matte   +6 more
doaj   +1 more source

Ebstein\u27s anomaly may be caused by mutations in the sarcomere protein gene MYH7

Ebstein\u27s anomaly is a rare congenital heart malformation characterised by adherence of the septal and posterior leaflets of the tricuspid valve to the underlying myocardium.
Moorman AFM, Helderman-van den Enden ATJM, Sperling SR, Goodship J, Mulder BJM, van Engelen K, van de Meerakker JBA, Keavney B, Klaassen S, Postma AV, Vliegen HW, Baars MJH, Sels JW, Roos-Hesselink JW, Rahman T, Bauer U, Pickardt T   +16 more
core   +2 more sources

T3-bound TRs (T3/TRs) repress TEAD-induced activity of the MYH7 promoter.

, 2014
(A) and (B) T3/TRβ1 represses promoter activity of the MYH7 gene induced by TEAD-3 (A) or TEAD-1 (B). MYH7-CAT (wild-type) was transfected into CV-1 cells along with the expression plasmid for human TRβ1, mouse TEAD-3, or TEAD-1 ...
Hiroyuki Iwaki (335243), Akio Matsushita (335242), Keiko Ishizuka (335246), Hirotoshi Nakamura (335250), Shigekazu Sasaki (335241), Hiroko Misawa (335240), Hideyuki Matsunaga (335244), Kenji Ohba (255704), Takafumi Suda (509192), Yutaka Oki (308231)   +9 more
core   +2 more sources

A polymorphism of the MYH7 gene

Nucleic Acids Research, 1990
M A, Siewertsen, H P, Vosberg, D W, Cox
openaire   +3 more sources

Report on the Post-Translational Modifications (PTMs) Prediction in Hypertrophic Cardiomyopathy-Associated Proteins MYH7, MYBPC3, TNNT2, and TNNI3, and Five Unknown PTMs in MYH7 (K129, K1451) and MYBPC3 (K14, R44, T705)

Cardiogenetics
In this study, we have performed computational PTM analysis on a panel of hypertrophic cardiomyopathy (HCM)-associated proteins: MYH7, MYBPC3, TNNT2, and TNNI3.
Natasha Trajkovska, Lenche Jovova, Done Stojanov   +2 more
doaj   +1 more source

Gut microbiota-mediated betaine regulates skeletal muscle fiber type transition by affecting m6A RNA methylation and Myh7 expression

Gut Microbes
Skeletal muscle fiber composition is essential for maintaining muscle function and overall health. Growing evidence underscores the pivotal role of the gut-muscle axis in mediating the influence of gut microbiota on skeletal muscle development.
Chao Yan, Yilong Yao, Zhaobo Zhang, Fanqinyu Li, Danyang Fan, Wen Liu, Xinhao Fan, Lingna Xu, Yanwen Liu, Shilong Wang, Mengling Hu, Yalan Yang, Zhonglin Tang   +12 more
doaj   +1 more source

Sex-Specific Expression Patterns of MYH6 and MYH7 Gene Transcripts in Large Cohorts of Non-Failing and Failing Human Left Ventricular Tissues

Journal of Cardiovascular Development and Disease
The transcriptional regulation of MYH6 and MYH7 genes has been extensively investigated in healthy versus failing hearts; however, their expression dynamics in healthy human hearts across age and sex, particularly in the context of cardiovascular risk ...
Zdenko Červenák, Ján Somorčík, Yashar Jalali, Žaneta Zajacová, Marian Baldovič, Andrea Gažová, Ján Kyselovič   +6 more
doaj   +1 more source

Hypertrophic Cardiomyopathy is a Disease of Sarcomere Proteins. [PDF]

Methodist Debakey Cardiovasc J
Marian AJ.
europepmc   +1 more source

Model Matters: Genetic Architecture and Cardiovascular Physiology in Translational Medicine. [PDF]

JACC Basic Transl Sci
Kleinbongard P, Vilahur G.
europepmc   +1 more source