Results 101 to 110 of about 16,475 (253)

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

iNew Medicine, EarlyView.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng, Wenhui Zhao, Min Wang, Xianwen Wang   +3 more
wiley   +1 more source

Impact of perioperative low-molecular-weight heparin therapy on clinical events of elderly patients with prior coronary stents implanted > 12 months undergoing non-cardiac surgery: a randomized, placebo-controlled trial

BMC Medicine
Background Little is known about the safety and efficacy of discontinuing antiplatelet therapy via LMWH bridging therapy in elderly patients with coronary stents implanted for > 12 months undergoing non-cardiac surgery. This randomized trial was designed
Bin Wang, Yanhui Su, Cong Ma, Lining Xu, Qunxia Mao, Wenjia Cheng, Qingming Lu, Ying Zhang, Rong Wang, Yan Lu, Jing He, Shihao Chen, Lei Chen, Tianzhi Li, Linggen Gao   +14 more
doaj   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

A Therapeutic Dilemma: Catastrophic ST‐Elevation Myocardial Infarction Following Antiplatelet Therapy Interruption in a Patient With JAK2‐Positive Polycythemia Vera

Clinical Case Reports
Polycythemia vera is associated with a thrombotic–hemorrhagic paradox. We report a 75‐year‐old woman with recurrent ST‐elevation myocardial infarction and stent thrombosis after premature dual antiplatelet therapy interruption.
Behrouz zarei, Amirhossein Rezaei Latifi, Mohammad Salari   +2 more
doaj   +1 more source

Diagnosis and treatment of coronary spasm in China: a case report

Frontiers in Cardiovascular Medicine
BackgroundCoronary vasospasm (CVS) is a common cardiovascular condition, yet its implications should not be underestimated. Regrettably, the current diagnostic and treatment standards for CVS in China are not standardized, severely affecting the quality ...
Hongyang Zhang, Hongyang Zhang, Xianglin Ye, Xianglin Ye, Haifeng Pei, Haifeng Pei   +5 more
doaj   +1 more source

Compressed Sensing‐Accelerated 3.0 T Noncontrast‐Enhanced CMRA: Diagnostic Efficacy for Coronary Artery Stenosis

iRADIOLOGY, EarlyView.
This bar chart illustrates the diagnostic performance of coronary magnetic resonance angiography (CMRA) for detecting ≥ 50.00% coronary artery stenosis at the segment, vessel, and patient levels, including sensitivity, specificity, positive predictive value, negative predictive value, and accuracy.
Zhengfu Wang, Yue Zhu, Yi Yin, Zewang Li, Mingming Huang, Bo Gao   +5 more
wiley   +1 more source

Myocardial bridging in obstructive hypertrophic cardiomyopathy: a risk factor for myocardial fibrosis

BMC Medicine
Background Myocardial bridging (MB) is common in patients with hypertrophic cardiomyopathy (HCM). There are sparse data on the impact of MB on myocardial fibrosis in HCM.
Changpeng Song, Shengwei Wang, Xinli Guo, Manyun Huang, Xinxin Zheng, Jie Lu, Keshan Ji, Shihua Zhao, Jingang Cui, Shuiyun Wang, Xiaohong Huang   +10 more
doaj   +1 more source

Performance of Free‐Running Cardiac and Respiratory Motion‐Resolved Whole‐Heart 5D MRI in Congenital Heart Disease Patients Using a Gadolinium Enhanced Fast‐Interrupted Steady‐State Sequence

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The performance of 5D imaging in CHD has been previously demonstrated using ferumoxytol rather than gadolinium. Purpose To evaluate the performance of gadolinium enhanced 5D MRI relative to 2D and 3D MRI in CHD patients. Study Type Retrospective.
Christopher W. Roy, Eva Vogeli, Alissia Megalo, Fabienne Dirbach, Jessica A. M. Bastiaansen, Jérôme Yerly, Marco Mueller, David Rodrigues, Jean‐Baptiste Ledoux, Juerg Schwitter, Milan Prša, Estelle Tenisch, Tobias Rutz, Matthias Stuber   +13 more
wiley   +1 more source