Results 111 to 120 of about 16,475 (253)
Abstract Background This study investigated the cross‐sectional association between periodontal status and left ventricular (LV) geometry and function, an early and prognostically relevant marker of cardiovascular disease. Methods Data were drawn from two population‐based cohorts in the Study of Health in Pomerania (SHIP): SHIP‐START‐2 (N = 2333) and ...
Maja Trost +8 more
wiley +1 more source
Abstract Background Transitions of care (TOC) between hospital and community settings are high‐risk periods for medication‐related problems (MRPs), often caused by inadequate information transfer between healthcare settings. Community pharmacists are well positioned to support continuity of care; however, they are frequently excluded from the ...
Melanie Bailey +3 more
wiley +1 more source
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
Multiomics Insights Into AL Amyloidosis
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang +6 more
wiley +1 more source
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du +10 more
wiley +1 more source
Mapping Causal Biology: Mendelian Randomization in the Era of Big Data
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen +10 more
wiley +1 more source
A Simple, Dynamic Geometric Phantom for MRI and CT Reconstruction Pipelines: Beyond Shepp–Logan
ABSTRACT A customizable, dynamic geometric phantom was developed to bridge the gap between simplistic static phantoms and highly realistic, complex 4D solutions. The phantom enables initial testing, helps detect implementation errors, and supports quantitative evaluation of new dynamic acquisition and reconstruction methods.
Tamás Hakkel +4 more
wiley +1 more source
ABSTRACT Purpose To develop a unified image reconstruction framework that bridges real‐time and gated cardiac MRI, including quantitative MRI. Methods We introduce generative multitasking, which learns subject‐ and dataset‐specific implicit neural temporal bases from sequence timings and an interpretable latent space for cardiac and respiratory motion.
Xinguo Fang, Anthony G. Christodoulou
wiley +1 more source
Early disease stages showed limited cortical atrophy and enrichment of synaptic and calcium signaling pathways, whereas advanced stages demonstrated widespread cortical degeneration associated with immune activation and extracellular matrix remodeling.
Yi Ji +6 more
wiley +1 more source
Myocardial infarction associated with myocardial bridging: A case report
Wanglu Bian, Yanming Wu, Biao Wang
doaj +1 more source

