Results 131 to 140 of about 145,724 (263)

Caffeic acid mitigates myocardial fibrosis via suppressing MAPKs/CREB-mediated inflammation in myocardial ischemia-reperfusion injury mice. [PDF]

Chin Med
Xiang M, Ouyang X, Song S, Yang M, Sarapultsev A, Luo S, Dong Y, Hu D.   +7 more
europepmc   +1 more source

The Vicious Cycle of Arrhythmia and Myocardial Fibrosis [PDF]

European Journal of Heart Failure, 2019
Piek, Arnold, Sillje, Herman H. W., de Boer, Rudolf A.   +2 more
openaire   +3 more sources

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

ADAMTS4 mediates LPS-induced cardiac injury and myocardial fibrosis through proteolytic cleavage of TSP1. [PDF]

Clin Transl Med
Zhang ZW, Wan SY, Li W, Lu X, Chen R, Xing X, Lai W, Sheng SY, Mosebetsi MM, Meng QT, Lu ZL, Fan D, Jiang WL.   +12 more
europepmc   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu, Zhenbang Gu, Wengen Zhu, Shenghui Feng   +3 more
wiley   +1 more source

Multiple triggering mechanisms of myocardial fibrosis: Comparison and integration in different disease contexts. [PDF]

iScience
Zhao B, Chen X, Feng S, Pang J, Liu H, Yang H, Li W, Chen H.   +7 more
europepmc   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

Natural Products Targeting Myocardial Fibrosis: Pharmacological Basis, Molecular Mechanisms and Translational Barriers. [PDF]

Int J Mol Sci
Long T, Ma J, Hu W, Wang Q, Xie Z, Wu S, Wu H.   +6 more
europepmc   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Focal Myocardial Fibrosis Mimicking Hypertrophy in INOCA and the Energetic Cost of Supranormal Ejection Fraction. [PDF]

JACC Case Rep
Nguyen TH, Nakamura T, Sato A.
europepmc   +1 more source