Results 271 to 280 of about 218,133 (348)

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

PINP levels in patients with newly diagnosed heart failure are associated with myocardial fibrosis and clinical outcomes. [PDF]

BMC Cardiovasc Disord
Liu M, Liu H, Du Q, Lei S, Hu T, Geng J, Zhang Q.   +6 more
europepmc   +1 more source

Magnetocardiography combined with machine learning for pulmonary hypertension detection and improved short‐term risk assessment

Interdisciplinary Medicine, EarlyView.
Magnetocardiography (MCG) enables non‐invasive mapping of cardiac magnetic fields. In this study, an MCG‐based machine learning model detects pulmonary hypertension with robust performance. Furthermore, MCG features may improve the accuracy of short‐term risk assessment.
Yuankun Qi, Jiaqi Liang, Kai Ma, Xiaoyu Hu, Yu Zhang, Xiaole Han, Dong Xu, Xu Zhang, Xiaopei Cui, Min Xiang, Hongyu Zhang, Jiancheng Fang   +11 more
wiley   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

The Role of Myocardial Fibrosis and Bioenergetic Dysfunction in Heart Failure Prognosis: A Study Protocol. [PDF]

Cureus
Barbosa M, Melicio A, Matias A, Santos M, Lopes JM, Aguiar L, Ferreira J, Inácio Â, Bicho M, Falcão LM.   +9 more
europepmc   +1 more source

Myocardial interstitial fibrosis in experimental uremia—Implications for cardiac compliance

, 1988
Gerhard Mall, M. Rambausek, Andrea Neumeister, Sylvia Kollmar, F. Vetterlein, Eberhard Ritz   +5 more
openalex   +1 more source

Cardiac MR Fingerprinting at 0.55T Using a Deep Image Prior for Joint T1, T2, and M0 Mapping

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background 0.55T systems offer unique advantages and may support expanded access to cardiac MRI. Purpose To assess the feasibility of 0.55T cardiac MR Fingerprinting (MRF), leveraging a deep image prior reconstruction to mitigate noise. Study Type Phantom and prospective in vivo assessment.
Zhongnan Liu, Zexuan Liu, Imran Rashid, Mauricio Stanzione Galizia, Christopher Scoma, William Truesdell, Prachi Agarwal, Nicole Seiberlich, Liyue Shen, Jesse Hamilton   +9 more
wiley   +1 more source

Acute binge alcohol increases risk of arrhythmias and myocardial fibrosis in a mouse model of arrhythmogenic cardiomyopathy. [PDF]

Am J Physiol Heart Circ Physiol
Shiel EA, Farra W, Medarev S, Ariyaratne GHDN, Cannon EN, Steiner JL, Chelko SP.   +6 more
europepmc   +1 more source

Towards Clinical Translation of Intravoxel Incoherent Motion MRI: Acquisition and Analysis Consensus Recommendations

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Intravoxel incoherent motion (IVIM) MRI allows for simultaneous assessment of tissue microcirculation (perfusion) and diffusion of water. In single‐center studies, IVIM has shown great potential for diagnosis, treatment outcome prediction, and treatment monitoring for many different diseases and organs.
Eric E. Sigmund, Susanne S. Rauh, Mami Iima, Christian Federau, Diego Hernando, Oscar Jalnefjord, Jacobus F. A. Jansen, Jonas Jasse, Neil Peter Jerome, Misha P. T. Kaandorp, Sila Kurugol, Frederik B. Laun, Mira M. Liu, Alexandra Ljimani, Thoralf Niendorf, David A. Reiter, Mohammed Salman Shazeeb, Amita Shukla‐Dave, Julia Stabinska, Andreas Wetscherek, Peter T. While, Dan Wu, Denis Le Bihan, Oliver J. Gurney‐Champion   +23 more
wiley   +1 more source

Targeting SYK with miR-512-3p provides therapeutic potential in myocardial fibrosis. [PDF]

Sci Rep
Li W, Yang W, Hou F, Li Y, Yang Y, Narigele, Nie Y, Zhi L, Liu J, Lu Y, Wu R.   +10 more
europepmc   +1 more source