Results 251 to 260 of about 696,855 (303)

S100A9 promotes pulmonary arterial hypertension by regulating mitochondria–endoplasmic reticulum interaction‐mediated inflammatory injury of endothelial cells

Interdisciplinary Medicine, EarlyView.
Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong, Long Chen, Yiting Zhao, Xiaohe Wang, Qiang Yuan, Xiaofeng Fang, Liuyi Li, Yinbo Xu, Shumei Jiang, Guangwen Xu, Ke Meng, Delong Wang, Kangli Cao, Jianlong Sheng, Liling Guo, Shichun Shen   +15 more
wiley   +1 more source

Epicardial adipose tissue density, myocardial fibrosis, and heart failure with preserved ejection fraction in postmenopausal women: a mediation analysis. [PDF]

Quant Imaging Med Surg
Jiang JS, Li L, Wang XY, Ruan XW, Zheng KL, Gao D, Huang S, Wang TL, Qi RX.   +8 more
europepmc   +1 more source

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan, Meryem İlkay Karagül, Hatice Oruç Demirbağ, Ebru Balli   +3 more
wiley   +1 more source

Comment on "Apical Sparing of Longitudinal Strain and Myocardial Fibrosis in Hypertensive Patients and Spontaneously Hypertensive Rats: Based on Speckle Tracking and Histological Analysis". [PDF]

Clin Cardiol
Bilal H.
europepmc   +1 more source

Detailed Association Between Electrocardiogram Abnormality and Primary Myocardial Fibrosis. [PDF]

Clin Cardiol
Nomoto Y, Kataoka N, Imamura T.
europepmc   +1 more source

FGF23 Controls Myocardial Fibrosis Progression via Promoting Cardiac Fibroblast Proliferation and Activation in Mice. [PDF]

Biology (Basel)
Shen L, Hu M, Xue M, Li S.
europepmc   +1 more source

Apical myocardial fibrosis burden identifies a high-risk phenotype and predicts cardiac mortality after LVAD implantation. [PDF]

ESC Heart Fail
Demir İ, Ecemiş B, Zorba A, Barış Iİ, Keskin B, Cantürk E, Yıldız Y, Karaca İO, Erkanlı K.   +8 more
europepmc   +1 more source

Evaluating left ventricular function and myocardial fibrosis in hypertrophic obstructive cardiomyopathy with corrected myocardial work. [PDF]

Echo Res Pract
Zhang X, Fang L, Xie Y, Li Y, Li H, Liu M, Sun C, Yang Y, Zhang R, Xu J, Wang J, Zhang L, Lv Q, Chen S, Wu W, Xie M.   +15 more
europepmc   +1 more source

Association Between HIV Infection Duration and Left Ventricular Concentric Remodeling and Myocardial Fibrosis: A Cross-Sectional Study Using Cardiac MRI. [PDF]

J Magn Reson Imaging
Deng C, Sun W, Gao T, Chen H, Liu L, Li R.   +5 more
europepmc   +1 more source

Targeting Hypertensive Myocardial Fibrosis

High Blood Pressure & Cardiovascular Prevention, 2005
In normal myocardium, myocytes represent only one-third of all cells, with the remaining two-thirds including fibroblasts and small cellular populations. While several weeks post partum the myocyte count stops increasing, the connective tissue cell count does not. In the early phases of arterial hypertension, adaptive left ventricular (LV) hypertrophy (
M.M. Ciulla, R. Paliotti, C. Cuspidi
openaire   +2 more sources