Results 41 to 50 of about 218,133 (348)

EGCG Alleviates Obesity-Induced Myocardial Fibrosis in Rats by Enhancing Expression of SCN5A

open access: yesFrontiers in Cardiovascular Medicine, 2022
ObjectObesity is an increase in body weight beyond the limitation of skeletal and physical requirement, as the result of an excessive accumulation of fat in the body. Obesity could increase the risk of myocardial fibrosis. (-)-Epigallocatechin-3-gallate (
Haoan Yi   +10 more
doaj   +1 more source

Non-Ischemic Myocardial Fibrosis in End-Stage Kidney Disease Patients: A New Perspective

open access: yesKidney and Dialysis, 2023
Cardiovascular medicine, especially for ischemic heart disease, has evolved and advanced over the past two decades, leading to substantially improved outcomes for patients, even those with chronic kidney disease.
Kenji Nakata, Nobuhiko Joki
doaj   +1 more source

Sphingosine 1-phosphate receptors: do they have a therapeutic potential in cardiac fibrosis? [PDF]

open access: yes, 2017
Sphingosine 1-phosphate (S1P) is a bioactive lipid that is characterized by a peculiar mechanism of action. In fact, S1P, which is produced inside the cell, can act as an intracellular mediator, whereas after its export outside the cell, it can act as ...
Frati, Alessia   +4 more
core   +2 more sources

Myocardial fibrosis in athletes—Current perspective [PDF]

open access: yesClinical Cardiology, 2020
AbstractSeveral previous studies suggested that prolonged and extensive physical activity might lead to increased prevalence of myocardial fibrosis in athletes. The review summarizes these studies focusing on common patterns of myocardial fibrosis observed in athletes, their potential causes and significance.
Łukasz A. Małek   +1 more
openaire   +4 more sources

The Prognostic Role of the Left Atrium in Hypertensive Patients with HFpEF: Does Function Matter More than Structure?

open access: yesLife
Background: In arterial hypertension (AH), adverse hemodynamic consequences in the left atrium (LA) are often observed. The prognostic significance of functional vs.
Artem Ovchinnikov   +6 more
doaj   +1 more source

Myocardial aging as a T-cell–mediated phenomenon [PDF]

open access: yes, 2017
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco   +15 more
core   +1 more source

Characterizing cardiac involvement in chronic kidney disease using CMR—a systematic review [PDF]

open access: yes, 2018
Purpose of Review: The aim of the review was to identify and describe recent advances (over the last 3 years) in cardiac magnetic resonance (CMR) imaging in patients with chronic kidney disease (CKD).
Mangion, Kenneth   +3 more
core   +1 more source

Hypereosinophilic syndrome and myocardial fibrosis [PDF]

open access: yesInteractive CardioVascular and Thoracic Surgery, 2008
A 62-year-old man was accepted to our institution because of hypereosinophilia, severe tricuspid regurgitation and isolated right restrictive myocardiopathy, with thrombi inside the right atrium and ventricle. Based on the diagnosis of hypereosinophilic syndrome plus eosinophilic myocarditis, the patient underwent a tricuspid valve repair and ...
Manuel, Carnero-Alcázar   +3 more
openaire   +2 more sources

Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. [PDF]

open access: yes, 2018
Non-human primates (NHPs) can serve as a human-like model to study cell therapy using induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs). However, whether the efficacy of NHP and human iPSC-CMs is mechanistically similar remains unknown.
Aguirre, Aitor   +19 more
core   +3 more sources

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