EGCG Alleviates Obesity-Induced Myocardial Fibrosis in Rats by Enhancing Expression of SCN5A
ObjectObesity is an increase in body weight beyond the limitation of skeletal and physical requirement, as the result of an excessive accumulation of fat in the body. Obesity could increase the risk of myocardial fibrosis. (-)-Epigallocatechin-3-gallate (
Haoan Yi +10 more
doaj +1 more source
Myocardial fibrosis in athletes: Additional considerations [PDF]
[No abstract]
Łukasz A. Małek +1 more
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Non-Ischemic Myocardial Fibrosis in End-Stage Kidney Disease Patients: A New Perspective
Cardiovascular medicine, especially for ischemic heart disease, has evolved and advanced over the past two decades, leading to substantially improved outcomes for patients, even those with chronic kidney disease.
Kenji Nakata, Nobuhiko Joki
doaj +1 more source
Sphingosine 1-phosphate receptors: do they have a therapeutic potential in cardiac fibrosis? [PDF]
Sphingosine 1-phosphate (S1P) is a bioactive lipid that is characterized by a peculiar mechanism of action. In fact, S1P, which is produced inside the cell, can act as an intracellular mediator, whereas after its export outside the cell, it can act as ...
Frati, Alessia +4 more
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Myocardial fibrosis in athletes—Current perspective [PDF]
AbstractSeveral previous studies suggested that prolonged and extensive physical activity might lead to increased prevalence of myocardial fibrosis in athletes. The review summarizes these studies focusing on common patterns of myocardial fibrosis observed in athletes, their potential causes and significance.
Łukasz A. Małek +1 more
openaire +4 more sources
Background: In arterial hypertension (AH), adverse hemodynamic consequences in the left atrium (LA) are often observed. The prognostic significance of functional vs.
Artem Ovchinnikov +6 more
doaj +1 more source
Myocardial aging as a T-cell–mediated phenomenon [PDF]
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco +15 more
core +1 more source
Characterizing cardiac involvement in chronic kidney disease using CMR—a systematic review [PDF]
Purpose of Review: The aim of the review was to identify and describe recent advances (over the last 3 years) in cardiac magnetic resonance (CMR) imaging in patients with chronic kidney disease (CKD).
Mangion, Kenneth +3 more
core +1 more source
Hypereosinophilic syndrome and myocardial fibrosis [PDF]
A 62-year-old man was accepted to our institution because of hypereosinophilia, severe tricuspid regurgitation and isolated right restrictive myocardiopathy, with thrombi inside the right atrium and ventricle. Based on the diagnosis of hypereosinophilic syndrome plus eosinophilic myocarditis, the patient underwent a tricuspid valve repair and ...
Manuel, Carnero-Alcázar +3 more
openaire +2 more sources
Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. [PDF]
Non-human primates (NHPs) can serve as a human-like model to study cell therapy using induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs). However, whether the efficacy of NHP and human iPSC-CMs is mechanistically similar remains unknown.
Aguirre, Aitor +19 more
core +3 more sources

