Results 21 to 30 of about 145,724 (263)

Myocardial fibrosis in athletes—Current perspective [PDF]

open access: yesClinical Cardiology, 2020
AbstractSeveral previous studies suggested that prolonged and extensive physical activity might lead to increased prevalence of myocardial fibrosis in athletes. The review summarizes these studies focusing on common patterns of myocardial fibrosis observed in athletes, their potential causes and significance.
Łukasz A. Małek   +1 more
openaire   +3 more sources

Lcz696 Alleviates Myocardial Fibrosis After Myocardial Infarction Through the sFRP-1/Wnt/β-Catenin Signaling Pathway

open access: yesFrontiers in Pharmacology, 2021
Background: Lcz696 (ARNI, angiotensin receptor–neprilysin inhibitor; sacubitril/valsartan) shows an inhibitory effect on fibrosis after myocardial infarction (MI). However, the underlying signaling mechanisms are poorly understood.
Jing Liu   +5 more
doaj   +1 more source

The Prognostic Role of the Left Atrium in Hypertensive Patients with HFpEF: Does Function Matter More than Structure?

open access: yesLife
Background: In arterial hypertension (AH), adverse hemodynamic consequences in the left atrium (LA) are often observed. The prognostic significance of functional vs.
Artem Ovchinnikov   +6 more
doaj   +1 more source

EGCG Alleviates Obesity-Induced Myocardial Fibrosis in Rats by Enhancing Expression of SCN5A

open access: yesFrontiers in Cardiovascular Medicine, 2022
ObjectObesity is an increase in body weight beyond the limitation of skeletal and physical requirement, as the result of an excessive accumulation of fat in the body. Obesity could increase the risk of myocardial fibrosis. (-)-Epigallocatechin-3-gallate (
Haoan Yi   +10 more
doaj   +1 more source

Diagnosis of Diffuse Myocardial Fibrosis [PDF]

open access: yesCirculation, 1959
Diffuse myocardial fibrosis is a disease of diverse etiology; the commonest cause is coronary artery disease. Physiologically, it produces a restriction of diastolic filling and thus resembles constrictive pericarditis and endocardial fibroelastosis. Clinically, it resembles constrictive pericarditis so closely that in many patients the differential ...
C S, BURWELL, E D, ROBIN
openaire   +2 more sources

Non-Ischemic Myocardial Fibrosis in End-Stage Kidney Disease Patients: A New Perspective

open access: yesKidney and Dialysis, 2023
Cardiovascular medicine, especially for ischemic heart disease, has evolved and advanced over the past two decades, leading to substantially improved outcomes for patients, even those with chronic kidney disease.
Kenji Nakata, Nobuhiko Joki
doaj   +1 more source

Effects of statins on functional capacity and cardiac remodeling in patients with heart failure and preserved ejection fraction: a randomized open-label pilot trial

open access: yesFrontiers in Cardiovascular Medicine
BackgroundSystemic inflammation is an essential pathophysiological factor of heart failure with preserved ejection fraction (HFpEF) that supports the use of statins.
Artem Ovchinnikov   +8 more
doaj   +1 more source

Myocardial fibrosis in stroke survivors [PDF]

open access: yesInternational Journal of Cardiology, 2015
Stroke survivors are most likely to die of cardiac death, yet few undergo comprehensive cardiac assessment to look for reversible causes. Myocardial fibrosis (MF) is not only the hallmark of cardiomyopathy, but also a substrate for sudden cardiac death, ventricular tachyarrhythmia and heart failure.
Wong, K.   +6 more
openaire   +3 more sources

Effects of empagliflozin on functional capacity, LV filling pressure, and cardiac reserves in patients with type 2 diabetes mellitus and heart failure with preserved ejection fraction: a randomized controlled open-label trial

open access: yesCardiovascular Diabetology
Background Clinical trials have established the prognostic benefits of sodium‒glucose cotransporter 2 (SGLT2) inhibitors in patients with type 2 diabetes mellitus (T2DM) and heart failure (HF) with preserved ejection fraction (HFpEF), although the ...
Artem Ovchinnikov   +6 more
doaj   +1 more source

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