High-sensitivity troponin I concentrations are a marker of an advanced hypertrophic response and adverse outcomes in patients with aortic stenosis [PDF]
AIMS: High-sensitivity cardiac troponin I (cTnI) assays hold promise in detecting the transition from hypertrophy to heart failure in aortic stenosis.
Lang, Chim C. +30 more
core +1 more source
MicroRNAs in fibrosis: opportunities and challenges [PDF]
MicroRNAs (miRNAs) are small, non-coding RNAs that mediate mRNA cleavage, translational repression or mRNA destabilisation and are around 22-25 nucleotides in length via partial complementary binding to the 3' untranslated region in target transcripts ...
O'Reilly, Steven, Steven O’Reilly
core +1 more source
Cardiac magnetic resonance (CMR) is a unique tool for non-invasive tissue characterization, especially for identifying fibrosis. To present the existing data regarding the association of electrocardiographic (ECG) markers with myocardial fibrosis ...
Tse, Gary +10 more
core +1 more source
Fragmented QRS complex as a marker of myocardial fibrosis in patients with coronary artery disease [PDF]
Aim– to analyze the relationship between fQRS and myocardial fibrosis in CAD patients using SPECT. Material and methods.Retrospectively, we have analyzed the anamnesis and examinations of 116 patients with suspected coronary heart disease.
Mariya S. Gordeeva +3 more
doaj +1 more source
Elucidating the role of circNFIB in myocardial fibrosis alleviation by endogenous sulfur dioxide
Background To investigate the role of circNFIB in the alleviation of myocardial fibrosis by endogenous sulfur dioxide (SO2). Methods We stimulated cultured neonatal rat cardiac fibroblasts with transforming growth factor-β1 (TGF-β1) and developed an in ...
Jia Liu +9 more
doaj +1 more source
Roles of Biomarkers in Myocardial Fibrosis [PDF]
Myocardial fibrosis is observed in various cardiovascular diseases and plays a key role in the impairment of cardiac function. Endomyocardial biopsy, as the gold standard for the diagnosis of myocardial fibrosis, has limitations in terms of clinical application.
Ding, Yuejia +7 more
openaire +2 more sources
Serum proteome profiling identifies novel and powerful markers of cystic fibrosis liver disease. [PDF]
Cystic Fibrosis associated liver disease (CFLD) develops in approximately 30% of CF patients. However, routine sensitive diagnostic tools for CFLD are lacking. Within this study, we aimed to identify new experimental biomarkers for the detection of CFLD.
Richard Schulz +26 more
core +1 more source
AIMS Myocardial involvement is common in patients with systemic sclerosis (SSc) and causes myocardial fibrosis and subtle ventricular dysfunction.
Gastl, Mareike +15 more
core +1 more source
Evaluation of myocardial fibrosis by cardiac magnetic resonance imaging in patient with myotonic dystrophy type 1 [PDF]
Objective: To evaluate myocardial fibrosis by cardiac magnetic resonance (CMR) in the patients with myo-tonic dystrophy type 1 (DM1), and compare the value of CMR and ECG.
HUANG Shaohua, LIANG Zonghui, TONG Huan, GUAN Xueni, GUO Ying, ZHANG Yan, CAO Bin, SUN Yumin
doaj +1 more source
Non-invasive imaging of fibrosis with positron emission tomography in a rat model with systemic hypertension and myocardial fibrosis [PDF]
Heart failure is one of the leading causes of death worldwide. Hypertension can initiate myocardial remodelling processes which, often via fibrotic triggers through the renin-angiotensin-aldosterone system, can lead to the development of heart failure. A
Balogh, Viktoria
core +1 more source

