Results 41 to 50 of about 696,855 (303)

Diagnosis of Diffuse Myocardial Fibrosis [PDF]

Circulation, 1959
Diffuse myocardial fibrosis is a disease of diverse etiology; the commonest cause is coronary artery disease. Physiologically, it produces a restriction of diastolic filling and thus resembles constrictive pericarditis and endocardial fibroelastosis. Clinically, it resembles constrictive pericarditis so closely that in many patients the differential ...
C S, BURWELL, E D, ROBIN
openaire   +2 more sources

Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosis [PDF]

, 2014
Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. The interaction of TG2 with the heparan sulfate proteoglycan syndecan-4 (Sdc4) regulates the cell surface trafficking, localization, and ...
Schroeder, N, Johnson, TS, Verderio, EAM, Funck, M, Scarpellini, A, Burhan, I, Huang, L   +6 more
core   +1 more source

Non-Ischemic Myocardial Fibrosis in End-Stage Kidney Disease Patients: A New Perspective

Kidney and Dialysis, 2023
Cardiovascular medicine, especially for ischemic heart disease, has evolved and advanced over the past two decades, leading to substantially improved outcomes for patients, even those with chronic kidney disease.
Kenji Nakata, Nobuhiko Joki
doaj   +1 more source

Lung Cancer in Pulmonary Fibrosis: Tales of Epithelial Cell Plasticity [PDF]

, 2011
Lung epithelial cells exhibit a high degree of plasticity. Alterations to lung epithelial cell function are critically involved in several chronic lung diseases such as pulmonary fibrosis.
Königshoff, M., Melanie Königshoff, Königshoff, Melanie   +2 more
core   +1 more source

Effects of statins on functional capacity and cardiac remodeling in patients with heart failure and preserved ejection fraction: a randomized open-label pilot trial

Frontiers in Cardiovascular Medicine
BackgroundSystemic inflammation is an essential pathophysiological factor of heart failure with preserved ejection fraction (HFpEF) that supports the use of statins.
Artem Ovchinnikov, Artem Ovchinnikov, Alexandra Potekhina, Olga Svirida, Tatiana Arefieva, Tamila Martynyuk, Fail Ageev, Marijana Tadic, Evgeny Belyavskiy   +8 more
doaj   +1 more source

Myocardial fibrosis in stroke survivors [PDF]

International Journal of Cardiology, 2015
Stroke survivors are most likely to die of cardiac death, yet few undergo comprehensive cardiac assessment to look for reversible causes. Myocardial fibrosis (MF) is not only the hallmark of cardiomyopathy, but also a substrate for sudden cardiac death, ventricular tachyarrhythmia and heart failure.
Wong, K., Sze, S., Wong, S., McSwiggan, S., Allgar, V., MacWalter, R., Struthers, A. D.   +6 more
openaire   +3 more sources

Non-invasive ventilation and clinical outcomes in cystic fibrosis: Findings from the UK CF registry [PDF]

, 2018
Background: Non-invasive ventilation (NIV) for respiratory failure and airway clearance is an established intervention in cystic fibrosis (CF), but its therapeutic benefit on lung function and survival remains under-investigated. Methods: Using data from
Bilton, D, Banya, W, Archangelidi, O, Cullinan, P, Carr, SB, Simmonds, NJ   +5 more
core   +1 more source

Effects of empagliflozin on functional capacity, LV filling pressure, and cardiac reserves in patients with type 2 diabetes mellitus and heart failure with preserved ejection fraction: a randomized controlled open-label trial

Cardiovascular Diabetology
Background Clinical trials have established the prognostic benefits of sodium‒glucose cotransporter 2 (SGLT2) inhibitors in patients with type 2 diabetes mellitus (T2DM) and heart failure (HF) with preserved ejection fraction (HFpEF), although the ...
Artem Ovchinnikov, Alexandra Potekhina, Anastasiia Filatova, Olga Svirida, Kristina Zherebchikova, Fail Ageev, Evgeny Belyavskiy   +6 more
doaj   +1 more source

Recent advances in positron emission tomography for detecting early fibrosis after myocardial infarction

Frontiers in Cardiovascular Medicine
Cardiac remodeling after myocardial infarction is one of the key factors affecting patient prognosis. Myocardial fibrosis is an important pathological link of adverse ventricular remodeling after myocardial infarction, and early fibrosis is reversible ...
Qiuyan Wu, Qiuyan Wu, Jialin Song, Jialin Song, Wenyan Liu, Wenyan Liu, Li Li, Li Li, Sijin Li, Sijin Li   +9 more
doaj   +1 more source

Low prevalence of fibrosis in thalassemia major assessed by late gadolinium enhancement cardiovascular magnetic resonance

Journal of Cardiovascular Magnetic Resonance, 2011
Background Heart failure remains a major cause of mortality in thalassaemia major. The possible role of cardiac fibrosis in thalassemia major in the genesis of heart failure is not clear.
Tanner Mark A, Carpenter John, Kirk Paul, Pennell Dudley J   +3 more
doaj   +1 more source