Results 11 to 20 of about 137,417 (261)

Hypertensive myocardial fibrosis [PDF]

Nephrology Dialysis Transplantation, 2005
A variety of cardiac structural and functional changes, such as increased left ventricular mass (LVM), left atrial and aortic root enlargement, LV dysfunction, impairment of coronary reserve and prolonged ven- tricular repolarization, have been described in patients with long-standing arterial hypertension [1,2].
CUSPIDI, CESARE, Ciulla, M, Zanchetti, A.   +2 more
openaire   +5 more sources

MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension

Cardiovascular Therapeutics, 2022
Background. Pulmonary arterial hypertension (PAH) usually causes right ventricular dysfunction, which is closely related to cardiac fibrosis. But cardiac fibrosis mechanism remains unclear.
Yi Tang, Xiaowei Huo, Junyu Liu, Yijin Tang, Min Zhang, Wenlin Xie, Zhaofen Zheng, Jin He, Jiayan Lian   +8 more
doaj   +1 more source

SARC Gene Mutation Is Associated With Myocardial Fibrosis Measured by Histopathology and Cardiac Magnetic Resonance in Patients With Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Sarcomere gene mutation and myocardial fibrosis are both associated with poorer clinical outcomes in patients with hypertrophic cardiomyopathy (HCM).
Manyun Huang, Jian Zhang, Changpeng Song, Shuiyun Wang, Zhou Zhou, Hongyue Wang, Shihua Zhao, Kunlun Yin, Li Li, Shujuan Yang, Xinxin Zheng, Jie Lu, Xiaohong Huang   +12 more
doaj   +1 more source

Methyl Ferulic Acid Attenuates Human Cardiac Fibroblasts Differentiation and Myocardial Fibrosis by Suppressing pRB-E2F1/CCNE2 and RhoA/ROCK2 Pathway

Frontiers in Pharmacology, 2021
Background: Myocardial fibrosis is a key pathological process after myocardial infarction, which leads to poor outcomes in patients at the end stage. Effective treatments for improving prognosis of myocardial fibrosis are needed to be further developed ...
Rongheng Liao, Zhen Qi, Ri Tang, Renrong Wang, Yongyi Wang   +4 more
doaj   +1 more source

Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis

Chinese Medicine, 2022
Background Myocardial fibrosis changes the structure of myocardium, leads to cardiac dysfunction and induces arrhythmia and cardiac ischemia, threatening patients’ lives.
Wenchuan Qi, Xiang Li, Yanrong Ren, Xueying Liu, Hongjuan Fu, Xiao Wang, Xiao Li, Jian Xiong, Qianhua Zheng, Dingjun Cai, Fanrong Liang   +10 more
doaj   +1 more source

Morphological and Functional Characteristics of Animal Models of Myocardial Fibrosis Induced by Pressure Overload

International Journal of Hypertension, 2020
Myocardial fibrosis is characterized by excessive deposition of myocardial interstitial collagen, abnormal distribution, and excessive proliferation of fibroblasts.
Yuejia Ding, Yuan Wang, Qiujin Jia, Xiaoling Wang, Yanmin Lu, Ao Zhang, Shichao Lv, Junping Zhang   +7 more
doaj   +1 more source

Fragmented QRS complex as a marker of myocardial fibrosis in patients with coronary artery disease [PDF]

Наука и инновации в медицине, 2022
Aim– to analyze the relationship between fQRS and myocardial fibrosis in CAD patients using SPECT. Material and methods.Retrospectively, we have analyzed the anamnesis and examinations of 116 patients with suspected coronary heart disease.
Mariya S. Gordeeva, Elena V. Parmon, Veronika A. Karlina, Darya V. Ryzhkova   +3 more
doaj   +1 more source

Elucidating the role of circNFIB in myocardial fibrosis alleviation by endogenous sulfur dioxide

BMC Cardiovascular Disorders, 2022
Background To investigate the role of circNFIB in the alleviation of myocardial fibrosis by endogenous sulfur dioxide (SO2). Methods We stimulated cultured neonatal rat cardiac fibroblasts with transforming growth factor-β1 (TGF-β1) and developed an in ...
Jia Liu, Ranran Zhang, Dahai Wang, Yi Lin, Cui Bai, Nana Nie, Shan Gao, Qiuye Zhang, Hong Chang, Chongmin Ren   +9 more
doaj   +1 more source

Myocardial fibrosis — a new component of heart remodeling in athletes?

Кардиоваскулярная терапия и профилактика, 2019
Studies on the myocardial fibrosis are a new direction in sports medicine. Much data indicate the formation of myocardial hypertrophy, as a natural myocardial response to systematic physical activity, while the fibrosis development in this category of ...
A. S. Sharykin, V. A. Badtieva, I. I. Trunina, I. M. Osmanov   +3 more
doaj   +1 more source

Evaluation of myocardial fibrosis by cardiac magnetic resonance imaging in patient with myotonic dystrophy type 1 [PDF]

Zhenduanxue lilun yu shijian, 2021
Objective: To evaluate myocardial fibrosis by cardiac magnetic resonance (CMR) in the patients with myo-tonic dystrophy type 1 (DM1), and compare the value of CMR and ECG.
HUANG Shaohua, LIANG Zonghui, TONG Huan, GUAN Xueni, GUO Ying, ZHANG Yan, CAO Bin, SUN Yumin
doaj   +1 more source