Results 51 to 60 of about 3,593 (184)

Intra-operative hypertension and myocardial injury and/or mortality and acute kidney injury after noncardiac surgery

, 2022
Background: Whether intra-operative hypertension causes postoperative complications remains unclear. Objective: We sought to assess whether there is an absolute systolic hypertensive threshold associated with increased odds of a composite of ...
Tetsuya Shimada, Ilker Ince, Daniel I. Sessler, İnce, İlker, Eva Rivas, Yang, Dongsheng, Dongsheng Yang, Edward J. Mascha, Turan, Alparslan, Alparslan Turan, Sessler, Daniel I., Mauro Bravo, Mascha, Edward J., Shimada, Tetsuya, Rivas, Eva, Bravo, Mauro   +15 more
core   +1 more source

Ivabradine in the Prevention, and Reduction in Size, of Perioperative Myocardial Injury in Patients Undergoing Orthopedic Surgery for Acute Fracture

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Perioperative myocardial injury is common after major noncardiac surgery and is associated with adverse outcomes. This study investigated the use of ivabradine in patients undergoing urgent surgery for fracture.
Rifly Rafiudeen, Peter Barlis, Raphael Hau, Sheran Vasanthakumar, Reginald Ng, Philip Wu, Mark Tacey, Adrian Banning, William van Gaal   +8 more
doaj   +1 more source

Myocardial injury after noncardiac surgery [PDF]

Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2022
P. J. Devereaux, Daniel Sessler, Manoj Lalu   +2 more
openaire   +2 more sources

Mechanisms underlying perioperative myocardial injury [PDF]

, 2022
Troponin is a biomarker for myocardial injury: it is associated with poor outcomes after noncardiac surgery, but the underlying mechanisms remain unclear.
May, S
core  

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao, Ling‐Ling Sun, Xiao‐Hua Shen, Min Wang, Mei‐Hui Wang, Lu‐Lu Liu, Kai Zhang   +6 more
wiley   +1 more source

Targeted heart rate control using the funny current inhibitor ivabradine to reduce morbidity in patients undergoing noncardiac surgery: study protocol for a phase 2a, triple-blind, placebo-controlled randomised trial

BJA Open
Background: Myocardial injury is strongly associated with excess morbidity and mortality after noncardiac surgery. Higher heart rate may result in perioperative myocardial injury through demand–supply mismatch.
Bernardo Bollen Pinto, Benjamin Shelley, Priyanthi Dias, Salma Begum, Florence Ennahdi-Elidrissi, Tom E.F. Abbott, Russell Hewson, Akshaykumar Patel, Kamran Khan, Rupert M. Pearse, Gareth L. Ackland, Bernardo Bollen Pinto, Benjamin Shelley, Priyanthi Dias, Salma Begum, Florence Ennahdi-Elidrissi, Russell Hewson, Anna Wozniak, Shaun M. May, Mareena Joseph, Agustine Miguel Saavedra, Tim Martin, Onika Ottley, Ana Santos, Fatima Seidu, Stéphanie Mulin, Stéphane Luise, Isabelle Pichon, John Daniels, Béatrice Gil-Wey, Soraya Bicher, Gaël Rais, Christene Aitken, Elizabeth Boyd, Patricia Griffen, Charlene Hamilton, Kathryn Valdeavella, Rhiannon McAreavey, Phillip McCall, Alfie Lloyd, Jocelyn Barr, Julie Buckley, Anne Marie Tiah, Henrike Janssen, Lisa Kandala, Angela Fitzpatrick, Alexander Lysomirski, Ahmed Ahltobi, Ana Gutierrez del Arroyo, Tom E.F. Abbott, Akshaykumar Patel, Kamran Khan, Rupert M. Pearse, Gareth L. Ackland   +53 more
doaj   +1 more source

Intraoperative Cardiac Events During Pediatric Cardiac Magnetic Resonance Imaging Under Anesthesia: A Retrospective Cohort Study

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Children with congenital heart disease (CHD) frequently undergo cardiac magnetic resonance imaging (MRI) under anesthesia. Although these procedures lack surgical stimulus, patients remain physiologically vulnerable, and the incidence of perioperative cardiovascular instability in this setting is poorly defined.
Theodora Wingert, Justine Liang, Kelly Feldman, Amelie Delaporte, Christine Nguyen‐Buckley, Tristan Grogan, Alexandre Joosten, John Paul Finn, Ihab Ayad   +8 more
wiley   +1 more source

Prehabilitation and Postoperative Outcomes in Major Surgery: A Retrospective Cohort Study Using MarketScan Claims Data

World Journal of Surgery, EarlyView.
Prehabilitation, including preoperative exercise, nutrition optimization, behavioral support, and smoking cessation services, may improve physiological reserve in patients undergoing surgery; however, large administrative and claims‐based real‐world evaluations across diverse procedure types have remained limited.
Meher Angez, Zayed Rashid, Odysseas P. Chatzipanagiotou, Areesh Mevawalla, Elemosho Abdulaziz, Qaidar Alizai, Timothy M. Pawlik   +6 more
wiley   +1 more source

Development and external validation of a perioperative clinical model for predicting myocardial injury after major abdominal surgery: A retrospective cohort study

Heliyon
Purpose: We aimed to develop and validate a predictive model for myocardial injury in individuals undergoing major abdominal surgery. Methods: This multicenter retrospective cohort analysis included 3546 patients aged ≥45 years who underwent major ...
Guifen Fan, Hanjin Lai, Xiwen Wang, Yulu Feng, Zhongming Cao, Yuxin Qiu, Shihong Wen   +6 more
doaj   +1 more source

Wearable Electronic Monitoring of Vital Signs in Hospitalised Adults: A Nursing Focused Scoping Review of Clinical, Economic and Implementation Outcomes

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To synthesise evidence on wearable devices for continuous vital signs monitoring in adult hospital inpatients, focusing on clinical effectiveness, nursing perspectives, workflow impact, patient experience and resource implications. Design Scoping review.
Sian Myfanwy Shaw, Sophie Bethan Shaw, Gillian Janes   +2 more
wiley   +1 more source