Results 101 to 110 of about 229,436 (314)

Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on "system to system" mode

, 2012
Background Shuanglong formula (SLF), a Chinese medicine composed of panax ginseng and salvia miltiorrhiza exhibited significant effect in the treatment of myocardial infarction (MI) in clinical. Because of the complex nature and lack of stringent quality
Yuan-Yuan Xie, Chen, Xi, Lv Shu-Feng, Liang, Q-L, Xu, Qing-Bo, Qing-Bo Xu, Liang Qiong-Lin, Cheng, Yi-Jun, Zhang, Q-L, Rong Gao, Xu, Q-B, Yi-Ming Wang, Zhang, Rong-Li, Xue Li, Gao, Rong, Lv, Shu-Feng, Zhang Rong-Li, Shu-Feng Lv, Xu Qing-Bo, Xi Chen, Xue-Mei Fan, Liang, Xiao-Ping, Liang Xiao-Ping, Jun Wu, Wu Jun, Xie Yuan-Yuan, Luo Guo-An, Zhang, Qing-Li, Zhang Hong-Yang, Xiao-Ping Liang, Gao, R, Luo, Guo-An, Xie, Yuan-Yuan, Zhang, Hong-Yang, Cheng, Y-J, Fan Xue-Mei, Zhang Qing-Li, Liang, Qiong-Lin, Xiao, Q-Z, Zhang, H-Y, Xiao, Qing-Zhong, Zhang, R-L, Yi-Jun Cheng, Chen, X, Wu, Jun, Xie, Y-Y, Luo, G-A, Qing-Li Zhang, Qiong-Lin Liang, Wang, Yi-Ming, Qing-Zhong Xiao, Lv, S-F, Gao Rong, Li Xue, Wang, Y-M, Wu, J, Fan, Xue-Mei, Cheng Yi-Jun, Hong-Yang Zhang, Wang Yi-Ming, Fan, X-M, Li, Xue, Liang, X-P, Guo-An Luo, Chen Xi, Xiao Qing-Zhong, Li, X, Rong-Li Zhang   +67 more
core   +1 more source

Improved Left Ventricular Aneurysm Repair with Cell- and Cytokine-Seeded Collagen Patches

Stem Cells International, 2018
Background. Engineered heart tissues (EHTs) present a promising alternative to current materials for surgical ventricular restoration (SVR); however, the clinical application remains limited by inadequate vascularization postimplantation.
Hui Qu, Bao-dong Xie, Jian Wu, Bo Lv, Jun-bo Chuai, Jian-zhong Li, Jun Cai, Hua Wu, Shu-lin Jiang, Xiao-ping Leng, Kai Kang   +10 more
doaj   +1 more source

Enhancing Blood Circulation With Epsilon‐Near‐Zero (ENZ) Materials via the Far‐Infrared Window of Human Skin

Advanced Science, EarlyView.
Epsilon‐near‐zero (ENZ) silicon carbide enables a selective far‐infrared emitter spectrally aligned with the human skin window around 10 µm for wavelength‐matched thermal therapy. In 25 within‐subject trials (50 hands) monitored by laser speckle contrast imaging, SiC increases blood perfusion by 30.2% versus a broadband graphite emitter while ...
Wen‐Teng Yao, Shan‐Chiao Yang, Ming‐Feng Tsai, Hsuen‐Li Chen   +3 more
wiley   +1 more source

Silent Myocardial Ischemia

Circulation Journal, 2009
Although much progress has been made in reducing mortality from ischemic cardiovascular disease, this condition remains the leading cause of death throughout the world. This might in part be due to the fact that over half of patients have a catastrophic event (heart attack or sudden death) as their initial manifestation of coronary disease ...
openaire   +3 more sources

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

Advanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng, Shiteng Cai, Jinfeng Gao, Sheng Zhao, Bohan Wei, Xueyi Weng, Zhengmin Wang, Qiaozi Wang, Qiyu Li, Chengzhi Han, Weiyan Li, Yiwen Tan, Yuyuan Fu, Meng Ji, Zheyong Huang, Yanan Song, Juying Qian, Junbo Ge   +17 more
wiley   +1 more source

Comprehensive age-specific metabolic phenotyping in myocardial infarction

BMC Cardiovascular Disorders
Aging is a main risk factor for the development of myocardial infarction (MI), with worse clinical outcomes. However, the understanding of age-related metabolic profiles in MI remains unclear. This study aimed to identify the clinical implications of age-
Xiaoxuan Bai, Ming Zeng, Tianyu Wu, Ying Lv, Chen Zhao, Xing Luo, Boling Yi, Huahui Ren, Yixuan Zhang, Liangxiao Xu, Xiuzhu Weng, Shan Zhang, Yuxiao Zhu, Sining Hu, Bo Yu, Haibo Jia   +15 more
doaj   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling

, 2001
The "metabolic cocktail" comprising glucose-insulin-potassium administrated at reperfusion reduces infarct size in the in vivo rat heart. We propose that insulin is the major component mediating this protection and acts via Akt prosurvival signaling ...
Sack, M.N., Yellon, D.M., Jonassen, A.K., Mjøs, O.D.   +3 more
core  

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

“Intrapericardial Approach” for Venous Outflow Reconstruction in Living‐Donor Liver Transplantation for Budd‐Chiari Syndrome: Surgical Techniques and LongTerm Outcomes

Annals of Gastroenterological Surgery, EarlyView.
Unlike deceased‐donor liver transplantation, living‐donor liver transplantation (LDLT) for Budd‐Chiari Syndrome (BCS) presents distinctive challenges in hepatic venous (HV)‐outflow reconstruction because diseased HV–inferior vena cava (IVC) cannot be entirely replaced with healthy donor vessels.
Koichiro Hata, Tetsuya Tajima, Satoshi Ogiso, Shinji Uemoto, Etsuro Hatano   +4 more
wiley   +1 more source