Results 71 to 80 of about 229,436 (314)

Association between triglyceride levels and hypertension in patients with coronary artery disease undergoing percutaneous coronary intervention: a retrospective cross-sectional study

Frontiers in Cardiovascular Medicine
BackgroundThis study aimed to investigate the association between serum triglyceride (TG) levels and the presence of hypertension in patients with coronary artery disease (CAD) and hypertension undergoing percutaneous coronary intervention (PCI ...
Zhanqun Gao, Zhanqun Gao, Zhanqun Gao, Yubo Gao, Yubo Gao, Chao Fang, Chao Fang, Chen Zhao, Chen Zhao, Dirui Zhang, Dirui Zhang, Wei Hao, Wei Hao, Haibo Jia, Haibo Jia, Sining Hu, Sining Hu, Bo Yu, Bo Yu   +18 more
doaj   +1 more source

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

Advanced Science, EarlyView.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

Effect of physical exercise on pain thresholds and plasma beta-endorphins in patients with silent and symptomatic myocardial ischaemia

, 1988
In a double-blind study, eight patients with symptomatic myocardial ischaemia and nine with asymptomatic myocardial ischaemia were compared during physical exercise under naloxone (6 mg i.v.) or placebo. Plasma beta-endorphin, cortisol and catecholamines
Roskamm, H., Droste, C., Meyer-Blankenburg, H., Greenlee, Mark W.   +3 more
core   +1 more source

Disparate effects of adhesion and degranulation of platelets on myocardial and coronary function in postischaemic hearts [PDF]

, 1998
Beside the major effect of acute thrombus formation, little is known about the interaction of platelets with the coronary endothelium in an ischaemia–reperfusion situation.
Welsch, Ulrich, Heindl, Bernhard, Zahler, Stefan, Becker, Bernhard F.   +3 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling

, 2009
Background: Mild therapeutic hypothermia following cardiac arrest is neuroprotective, but its effect on myocardial dysfunction that is a critical issue following resuscitation is not clear.
Meybohm, Patrick, Zitta, Karina, Matthias Gruenewald, Nguyen Tran, Grünewald, Matthias Lars, Martin Albrecht, Koch, Alexander, Karina Zitta, Lucius, Ralph, Scholz, Jens, Kai D Zacharowski, Patrick Meybohm, Bein, Berthold Helmut, Berthold Bein, Albrecht, Martin, Ralph Lucius, Jens Scholz, Alexander Koch, Zacharowski, Kai, Tran, Thi Hoai Nguyen   +19 more
core   +1 more source

Novel insights into the cardio-protective effects of FGF21 in lean and obese rat hearts [PDF]

, 2014
Aims: Fibroblast growth factor 21 (FGF21) is a hepatic metabolic regulator with pleotropic actions. Its plasma concentrations are increased in obesity and diabetes; states associated with an increased incidence of cardiovascular disease.
Muhammad F Bari, Bari Muhammad F., Jing Chen, Edward W. Hillhouse (519261), Bari, Muhammad F., Raghu Adya (519258), Patel Vanlata, Bhudia, Sunil K., Edward W Hillhouse, Harpal S Randeva, Vanlata Patel, Raghu Adya, Chen Jing, Manjunath Ramanjaneya, Bee K. Tan (417731), Ramanjaneya, Manjunath, Jing Chen (4762), Patel, Vanlata H., Ramanjaneya Manjunath, Harpal S. Randeva (417734), Randeva Harpal S., Muhammad F. Bari (417733), Tan, Bee K., Adya Raghu, Adya, Raghu, Tan Bee K., Bhudia Sunil K., Randeva, Harpal S., Bee K Tan, Manjunath Ramanjaneya (519259), Sunil K Bhudia, Sunil K. Bhudia (519260), Hillhouse Edward W., Vanlata Patel (519257), Hillhouse, Edward W., Chen, Jing   +35 more
core   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

DNMT1 deficiency promotes pulmonary vascular remodeling in pulmonary hypertension through epigenetic upregulation of BMP7

Respiratory Research
Background Pulmonary hypertension (PH) is a progressive cardiopulmonary disorder marked by pathological vascular remodeling, predominantly driven by the hyperproliferation of pulmonary artery smooth muscle cells (PASMCs).
Yong-Bing Wang, Lei Gao, Jia-Xin Wang, Zhe Mei, You-Li Fan, Xuan Gao, Jing Huang, Bin-Feng Sun, Yu-Fei Gao, Na Sun, Xiao-Dong Zheng, Bing-Xiang Wu   +11 more
doaj   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source