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Myocardial protection during myocardial revascularization: Preductal®MR

Медицинский совет, 2013
Myocardial revascularization procedures (coronary artery bypass surgery, percutaneous coronary intervention) raise the question of protecting the myocardium. Trimetazidine is an adequate method of myocardial protection.
Editorial Article
doaj   +1 more source

Comparative Analysis of the Effectiveness of Different Options for the Administration of Cardioplegic Solution during Surgical Correction of an Aortic Aneurysm Combined with Coronary Artery Lesions

Український журнал серцево-судинної хірургії, 2023
The aim. To determine the effectiveness of myocardial protection in various variants of administration of cardioplegic solution in patients with aortic aneurysms combined with coronary artery lesions. Materials and methods.
Ihor I. Zhekov, Oleh I. Sarhosh, Andrii V. Grytsiuk, Andrii I. Perepeliuk, Anatoliy V. Rudenko   +4 more
doaj   +1 more source

Diazoxide Post-conditioning Activates the HIF-1/HRE Pathway to Induce Myocardial Protection in Hypoxic/Reoxygenated Cardiomyocytes

Frontiers in Cardiovascular Medicine, 2021
Background: Previous studies have shown that diazoxide can protect against myocardial ischemia-reperfusion injury (MIRI). The intranuclear hypoxia-inducible factor-1 (HIF-1)/hypoxia-response element (HRE) pathway has been shown to withstand cellular ...
Xi-Yuan Chen, Xi-Yuan Chen, Jia-Qi Wang, Si-Jing Cheng, Yan Wang, Meng-Yuan Deng, Tian Yu, Hai-Ying Wang, Wen-Jing Zhou, Wen-Jing Zhou   +9 more
doaj   +1 more source

Mechanisms of Volatile Anesthetic-Induced Myocardial Protection [PDF]

, 2003
Volatile anesthetics protect myocardium against reversible and irreversible ischemic injury. Experimental evidence from several in vitro and in vivo animal models demonstrates that volatile agents enhance the recovery of stunned myocardium and reduce the
Gu, Weidong, Kersten, Judy R., LaDisa, John F., Ludwig, Lynda M., Pagel, Paul S., Tanaka, Katsuya, Warltier, David C.   +6 more
core   +1 more source

A modified technique for reducing the duration of ischemic time of the heart and myocardial reperfusion in multivalve correction combined with coronary grafting

Кардіохірургія та інтервенційна кардіологія, 2023
The aim – to develop and put into practice a method of reducing the ischemic time of the heart during long-term cardiac surgery interventions. Materials and methods. A modified technique of coronary artery bypass grafting has been developed for combined
P.M. Semeniv
doaj   +1 more source

Minimally Invasive Mitral Valve Surgery II: Surgical Technique and Postoperative Management. [PDF]

, 2016
Techniques for minimally invasive mitral valve repair and replacement continue to evolve. This expert opinion, the second of a 3-part series, outlines current best practices for nonrobotic, minimally invasive mitral valve procedures, and for ...
Agnihotri, Arvind K, Ailawadi, Gorav, Barnhart, Glenn R, Farivar, R Saeid, Fayers, Trevor M, Goldman, Scott M, Grossi, Eugene A, Guy, T Sloane, Hargrove, W Clark, Hummel, Brian W, Khan, Junaid H, Lehr, Eric J, Lewis, Clifton TP, Malaisrie, S Chris, Mehall, John R, Moront, Michael G, Murphy, Douglas A, Rodriguez, Evelio, Ryan, William H, Salemi, Arash, Segurola, Romualdo J, Shemin, Richard J, Smith, J Michael, Smith, Robert L, Weldner, Paul W, Wolfe, J Alan   +25 more
core   +1 more source

Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction

Nature Communications, 2019
The primary cause of heart failure is the loss of cardiomyocytes in the diseased adult heart. Previously, we reported that the miR-17-92 cluster plays a key role in cardiomyocyte proliferation.
F. Gao, M. Kataoka, N. Liu, T. Liang, Zhan-Peng Huang, Fei Gu, Jian Ding, Jianming Liu, Feng Zhang, Qing Ma, Yingchao Wang, Mingming Zhang, Xiaoyun Hu, J. Kyselovič, Xinyang Hu, W. Pu, Jian’an Wang, Jinghai Chen, Da-Zhi Wang   +18 more
semanticscholar   +1 more source

Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis

Cell Death and Disease, 2023
The glutathione (GSH) system is considered to be one of the most powerful endogenous antioxidant systems in the cardiovascular system due to its key contribution to detoxifying xenobiotics and scavenging overreactive oxygen species (ROS).
Ming-yue Tan, Yunfei Yin, Xiao Ma, Jun Zhang, Wanqian Pan, Minghao Tan, Yongjian Zhao, Tianke Yang, Tingbo Jiang, Hongxia Li   +9 more
semanticscholar   +1 more source

Modulation of Mitochondrial Bioenergetics in the Isolated Guinea Pig Beating Heart by Potassium and Lidocaine Cardioplegia: Implications for Cardioprotection [PDF]

, 2009
Mitochondria are damaged by cardiac ischemia/reperfusion (I/R) injury but can contribute to cardioprotection. We tested if hyperkalemic cardioplegia (CP) and lidocaine (LID) differently modulate mitochondrial (m) bioenergetics and protect hearts against ...
Aldakkak, Mohammed, Camara, Amadou K.S., Chen, Qun, Heisner, James S., Lesnefsky, Edward J., Stowe, David F.   +5 more
core   +2 more sources

Myocardial Protection: An Overview

The Journal of ExtraCorporeal Technology, 2000
The goals of myocardial protection during cardiac surgery are not only to facilitate the operation by providing a quiet bloodless field, thereby facilitating the precision of the operation, but also to avoid iatrogenic injury induced by cardiopulmonary bypass itself or by surgically imposed ischemia.
J, Vinten-Johansen, V H, Thourani
openaire   +2 more sources