Results 21 to 30 of about 2,538,825 (248)

Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI) [PDF]

, 2014
AimDespite prompt revascularization of acute myocardial infarction (AMI), substantial myocardial injury may occur, in part a consequence of ischaemia reperfusion injury (IRI). There has been considerable interest in therapies that may reduce IRI.
Singh, Satnam, Lim, Pitt O, Christopher Neil (433186), Bruce, M, Broadhurst, Paul, Madhani, Melanie; id_orcid, Nishat Siddiqi (7733786), Schwarz, Konstantin, Awsan, Noman, Jansen, Else, McPherson, Gladys, Dawson, Dana, Slattery, Elaine, Struthers, Allan, McDonald, Alison, Rhodes, Jonathan, Neil, Christopher, Toff, William, Bruce, M., Garg, Deepak, Siddiqi, N, Firoozi, Sami, Kaski, JC, Madhani, M., Nicholas Boon (7733804), Kaski, Juan-Carlo, Sofia Papadopoulou (7733789), Horowitz, J, Bennett, Lorraine, Horowitz, J., Frenneaux, Michael, Boon, N., Bruce, Margaret, Hildick-Smith, David, Lim, P., Neil, C., Nightingale, Peter, Pitt O. Lim (7733795), Graeme MacLennan (275485), Hannah, Andrew, Feelisch, M., Melanie Madhani (3851305), Roberts, Elved, Dawson, D, David Hildick-Smith (7733798), Madhani, M, Kaski, Juan Carlos, Lim, PO, Stewart, Andrew, Cooter, Nina, Rajendran, Sharmalar, Horowitz, John, Lang, Chim, Papadopoulou, Sofia A., NIAMI investigators, Jagpal, Baljit, Cotton, S, Siddiqi, N., Gonzalvez, Fatima, Feelisch, Martin, Madhani, Melanie, Boon, Nicholas, Nicholas Bunce (7733792), Brown, Sue, Roy, David, Bunce, N., Bunce, N, Papadopoulou, S, Dawson, D., Frenneaux, M., Michael Frenneaux (3576296), Davidson, Tracey, Siddiqi, Nishat, Dargie, Henry, Feelisch, M, Neil, C, Dana Dawson (7020656), Hildick-Smith, D., Frenneaux, M, Hildick-Smith, D, Bunce, Nicholas, NIAMI investigators (7733810), Cotton, Seonaidh, Seonaidh Cotton (503485), de Belder, Adam, Papadopoulou, S., Black, Marilyn, Kaski, J., Hogg, Duncan, Dautov, Rustem, Metcalfe, Malcolm, Bogle, Richard, Cotton, S., Boon, N, Martin Feelisch (358503), John Horowitz (7733801), Margaret Bruce (782483), Lim, Pitt O., MacLennan, G, Cotton, Seonaidh Claire, Juan Carlos Kaski (7733807), Maclennan, Graeme, Papadopoulou, Sofia, MacLennan, G.   +103 more
core   +1 more source

The role of signal transducer and activator of transcription-3 (STAT-3) in ischaemic and pharmacological preconditioning [PDF]

, 2006
Includes bibliographical references (leaves 150-177).Ischemic preconditioning is a protective mechanism whereby repetitive transient ischaemia confer protection against the subsequent prolonged lethal ischaemia that is observed during myocardial ...
Suleman, Naushaad
core   +1 more source

Effect of Del Nido cardioplegia solution on myocardial protection in adult cardiac surgery under cardiopulmonary bypass: a Meta-analysis

Di-san junyi daxue xuebao, 2021
Objective To compare the efficacy of Del Nido cardioplegia solution and conventional cardioplegia in adult patients. Methods Systematic searches were performed to identify related studies using PubMed, EMbase, Cochrane Library, International Clinical ...
XU Xu, WANG Weifan, YU Min, LI Yongnan
doaj   +1 more source

Myocardial Expression of Estrogen Receptor-mRNA Is Associated With Lower Markers of Post-operative Organ Damage in Young Patients With Congenital Cardiac Defect

Frontiers in Pediatrics, 2021
Background: Estrogen receptors (ERs) relate to cardio-protection in adults, but their role in younger patients is not known. We aimed to assess the myocardial expression of ERα- and ERβ- mRNA in young patients with congenital cardiac disease and to ...
Hatem Rouatbi, Nesrine Farhat, Ruth Heying, Jaime F. Vazquez-Jimenez, Anne-Simone Parent, Marie-Christine Seghaye   +5 more
doaj   +1 more source

COMPARISON OF THE EFFECT OF ANTEGRADE AND ANTEGRADE/RETROGRADE CARDIOPLEGIA ON THE OUTCOME OF CORONARY ARTERY BYPASS GRAFT SURGERY FOR SEVERE CORONARY ARTERY DISEASE

Pakistan Armed Forces Medical Journal, 2020
Objective: To compare the early outcome of Coronary Artery Bypass Graft surgery using a combination of antegrade and retrograde cardipoplegia with that utilizing antegrade cardioplegia alone in triple vessel coronary artery disease.
Ali Gohar Zamir, Asif Mahmood Janjua, Musfireh Siddiqeh, Farrah Pervaiz, Noor Shah, Muhammad Afsheen Iqbal, Muhammad Ashfaq   +6 more
doaj   +1 more source

Comparative Analysis of the Effectiveness of Different Options for the Administration of Cardioplegic Solution during Surgical Correction of an Aortic Aneurysm Combined with Coronary Artery Lesions

Український журнал серцево-судинної хірургії, 2023
The aim. To determine the effectiveness of myocardial protection in various variants of administration of cardioplegic solution in patients with aortic aneurysms combined with coronary artery lesions. Materials and methods.
Ihor I. Zhekov, Oleh I. Sarhosh, Andrii V. Grytsiuk, Andrii I. Perepeliuk, Anatoliy V. Rudenko   +4 more
doaj   +1 more source

Neutrophils incite and macrophages avert electrical storm after myocardial infarction [PDF]

, 2022
Sudden cardiac death, arising from abnormal electrical conduction, occurs frequently in patients with coronary heart disease. Myocardial ischemia simultaneously induces arrhythmia and massive myocardial leukocyte changes.
Schloss, Maximilian J., Foy, Brody H., Capen, Diane, Sosnovik, David E, Lewis, Andrew JM, Grune, Jana, Channon, Keith M, Timm, Kerstin, King, Kevin R., Neubauer, Stefan, Swirski, Filip K, Brown, Dennis, Swirski, Filip K., Ferreira, Vanessa M, Ellinor, Patrick T, Hulsmans, Maarten, Ott, Christiane, Nahrendorf, Matthias, Foy, Brody H, Channon, Keith M., Wojtkiewicz, Gregory R., Pulous, Fadi E., Milan, David J., Zhou, Yirong, Lewis, Andrew J. M., Aguirre, Aaron D, Calcagno, David M, Calcagno, David M., Rohde, David, Sosnovik, David E., Grune, Tilman, Yamazoe, Masahiro, Milan, David J, Higgins, John, Pulous, Fadi E, Zhang, Shuang, Iwamoto, Yoshiko, Aguirre, Aaron D., Shanmuganathan, Mayooran, Schloss, Maximilian J, Ellinor, Patrick T., Wojtkiewicz, Gregory R, Xiao, Ling, Vinegoni, Claudio, Herring, Neil, King, Kevin R, Ferreira, Vanessa M.   +46 more
core   +1 more source

Altered gene expression pattern in peripheral blood mononuclear cells in patients with acute myocardial infarction. [PDF]

, 2012
In the acute phase of STEMI, dozens of genes from several pathways linked with lipid/glucose metabolism, platelet function and atherosclerotic plaque stability show altered expression.
Burzynska, Beata, Kochanowski, Janusz, Michalak, Marcin, Gajda, Ewa, Winkler, Aleksandra, Maciejak, Agata, Kiliszek, Marek, Opolski, Grzegorz, Gora, Monika, Leszczynska, Agata   +9 more
core   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling [PDF]

, 2001
The "metabolic cocktail" comprising glucose-insulin-potassium administrated at reperfusion reduces infarct size in the in vivo rat heart. We propose that insulin is the major component mediating this protection and acts via Akt prosurvival signaling ...
Sack, M.N., Yellon, D.M., Jonassen, A.K., Mjøs, O.D.   +3 more
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