Results 31 to 40 of about 129,108 (303)

How early can myocardial iron overload occur in Beta thalassemia major?

, 2014
BACKGROUND: Myocardial siderosis is the most common cause of death in patients with beta thalassemia major(TM). This study aimed at investigating the occurrence, prevalence and severity of cardiac iron overload in a young Chinese population with beta TM.
Gaohui Yang, Pan Hongfei, He, T, Lai, Y, Peng, P, Liu Rongrong, Long, X, Taigang He, Tan Shaohong, Liu, R, Hongfei Pan, Yang Weijia, Xingjiang Long, Rongrong Liu, Lai Yongrong, Yang Gaohui, He Taigang, Weijia Yang, Yang, G, Xinhua Zhang, Tan, S, Liling Long, Anderson Lisa, Lisa Anderson, Long Xingjiang, Yang, W, Zhang, X, Anderson, L, Peng Peng, Yongrong Lai, Zhang Xinhua, Long Liling, Pan, H, Shaohong Tan, Long, L   +34 more
core   +1 more source

Myocardial Protection

Ismail A, Semien G.
europepmc   +2 more sources

Improved ventricular function during inhalation of PGI(2) aerosol partly relies on enhanced myocardial contractility [PDF]

, 2005
Inhaled prostacyclin (PGI(2)) aerosol induces selective pulmonary vasodilation. Further, it improves right ventricular ( RV) function, which may largely rely on pulmonary vasodilation, but also on enhanced myocardial contractility.
Thein, E., Kisch-Wedel, H., Kemming, G., Bruhn, S., Meisner, F., Meisner, D., Kreyling, W., Zwissler, B., Flondor, M., Kreyling, W.G., Zwissler, Bernhard, Hofstetter, C., Kemming, Gregor   +12 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Diazoxide Post-conditioning Activates the HIF-1/HRE Pathway to Induce Myocardial Protection in Hypoxic/Reoxygenated Cardiomyocytes

Frontiers in Cardiovascular Medicine, 2021
Background: Previous studies have shown that diazoxide can protect against myocardial ischemia-reperfusion injury (MIRI). The intranuclear hypoxia-inducible factor-1 (HIF-1)/hypoxia-response element (HRE) pathway has been shown to withstand cellular ...
Xi-Yuan Chen, Xi-Yuan Chen, Jia-Qi Wang, Si-Jing Cheng, Yan Wang, Meng-Yuan Deng, Tian Yu, Hai-Ying Wang, Wen-Jing Zhou, Wen-Jing Zhou   +9 more
doaj   +1 more source

Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis [PDF]

, 2006
The use of cyclo-oxygenase 2 selective nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with increased risk of acute myocardial infarction (AMI). The association between the risks of AMI with nonselective NSAIDs is less clear.
Madhok, R., Langhorne, P., Wu, O., Singh, G.   +3 more
core   +1 more source

Effects of swimming training on myocardial protection in rats

, 2023
Swimming is important for promoting and maintaining health, as it can increase the efficiency of the cardiovascular system and decrease the occurrence of cardiovascular diseases. The objective of the present study was to examine whether swimming training
Chang-Chi Lai, Chia-Yu Tang, Szu-Kai Fu, Wei-Chin Tseng, Kuo-Wei Tseng
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

A modified technique for reducing the duration of ischemic time of the heart and myocardial reperfusion in multivalve correction combined with coronary grafting

Кардіохірургія та інтервенційна кардіологія, 2023
The aim – to develop and put into practice a method of reducing the ischemic time of the heart during long-term cardiac surgery interventions. Materials and methods. A modified technique of coronary artery bypass grafting has been developed for combined
P.M. Semeniv
doaj   +1 more source