Results 11 to 20 of about 3,082,827 (354)

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology [PDF]

Basic Research in Cardiology, 2018
Due to its poor capacity for regeneration, the heart is particularly sensitive to the loss of contractile cardiomyocytes. The onslaught of damage caused by ischaemia and reperfusion, occurring during an acute myocardial infarction and the subsequent ...
A Ames 3rd, A Carvalho, A Gaspar, A Maulik, AA Neuhaus, AC Schinzel, AD Sloth, Arjun K. Ghosh, AS Hazell, B Ibanez, B Ibanez, Borja Ibanez, CC Smith, CE Murry, CP Baines, D Li, Daniel I. Bromage, Derek M. Yellon, DI Bromage, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, ET Chouchani, F Chauveau, F Chen, F Pedersen, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, GA Donnan, GA Donnan, Gerd Heusch, GF Baxter, GP Fadini, GW Stone, H Sandhu, HA Cabrera-Fuentes, Hans Erik Bøtker, HE Botker, Helen Maddock, I Eitel, J Aronowski, J Astrup, J Bai, J Inserte, J Johnsen, JC Wang, JE Jung, JL Saver, JM Vicencio, John Cunningham, JP Audia, JPG Sluijter, JS Balami, JV McGowan, K Szummer, KL Furie, L Zhang, M Fisher, M Gharanei, M Gharanei, M Schmidt, M Thielmann, Malcolm Walker, Marlene Wiart, Maryna V. Basalay, MD Ginsberg, Michel Ovize, MV Cohen, N Nighoghossian, P Kleinbongard, P Meybohm, PA Lapchak, PA Lapchak, Petra Kleinbongard, R Bell, R Bonita, R Chung, R Madonna, RA Kloner, Richard D. Carr, RM Bell, RM Bell, Robert M. Bell, RR Liu, RR Moustafa, S Lecour, S Pundik, SA Crone, Sandrine Lecour, Sapna Arjun, Sean M. Davidson, SI Savitz, SM Davidson, SM Davidson, SM Davidson, SM Davidson, SP Jones, TA Zelniker, VE O’Collins, VE O’Collins, VL Feigin, W Li, X Rossello, X Rossello, X Xu, Y Li, Z Vermeulen   +117 more
core   +7 more sources

Evaluation of Myocardial Protection in Prolonged Aortic Cross-Clamp Times: Del Nido and HTK Cardioplegia in Adult Cardiac Surgery [PDF]

Medicina
Background and Objectives: Effective myocardial protection is essential for successful cardiac surgery outcomes, especially in complex and prolonged procedures.
Murat Yücel, Emre Demir Benli, Kemal Eşref Erdoğan, Muhammet Fethi Sağlam, Gökay Deniz, Hakan Çomaklı, Emrah Uğuz   +6 more
doaj   +2 more sources

Comparison of routine del Nido cardioplegia vs two types of modified del Nido cardioplegias for myocardial protection among patients undergoing coronary artery bypass grafting (CABG) surgeries: A randomized double-blind clinical trial [PDF]

The Journal of ExtraCorporeal Technology
Background: The del Nido cardioplegia solution is a widely used method for myocardial protection in various settings. However, there is limited evidence of its effectiveness in adult cardiac surgery, and the baseline solution, Plasma Lyte A, is not ...
Ali Babar, Butt Salman Pervaiz, Nour Mohammad Ghazi, Khosravi Mohammad Bagher, Asmarian Naeimehossadat, Shoul Ali Raza, Kumar Arun, Darr Umer, Bhatnagar Gopal   +8 more
doaj   +2 more sources

Myocardial protection in cardiac surgery: a comprehensive review of current therapies and future cardioprotective strategies [PDF]

Frontiers in Medicine
Cardiac surgery with cardiopulmonary bypass results in global myocardial ischemia–reperfusion injury, leading to significant postoperative morbidity and mortality.
Pascal Chiari, Pascal Chiari, Jean-Luc Fellahi, Jean-Luc Fellahi   +3 more
doaj   +2 more sources

Corrigendum: Diazoxide post-conditioning activates the HIF-1/HRE pathway to induce myocardial protection in hypoxic/reoxygenated cardiomyocytes [PDF]

Frontiers in Cardiovascular Medicine, 2023
Xi-Yuan Chen, Xi-Yuan Chen, Jia-Qi Wang, Si-Jing Cheng, Yan Wang, Meng-Yuan Deng, Tian Yu, Hai-Ying Wang, Wen-Jing Zhou, Wen-Jing Zhou   +9 more
doaj   +2 more sources

Aortic Dissection Type a in Combination with Acute Anterior Myocardial Infarction. Myocardial Protection [PDF]

Journal of Biomedical & Clinical Research, 2023
Acute aortic dissection is an extremely serious condition with a high mortality risk. Symptoms may mimic other emergencies such as myocardial ischemia, often leading to misdiagnosis.
Georgi Stoitsev, Veselin Gavrilov, Vassil Gegouskov   +2 more
doaj   +3 more sources

Myocardial Protection in Cardiac Surgery-Hindsight from the 2020ies.

European Journal of Cardio-Thoracic Surgery, 2023
Myocardial protection and specifically cardioplegia have been extensively investigated in the beginnings of cardiac surgery. After cardiopulmonary bypass had become routine, more and more cardiac operations were possible, requiring reliable and ...
M. Mukharyamov, Ulrich Schneider, H. Kirov, T. Caldonazo, T. Doenst   +4 more
semanticscholar   +1 more source

MiR-486 attenuates cardiac ischemia/reperfusion injury and mediates the beneficial effect of exercise for myocardial protection.

Molecular Therapy, 2022
Exercise and its regulated molecules have myocardial protective effects against cardiac ischemia/reperfusion (I/R) injury. The muscle-enriched miR-486 was previously identified to be upregulated in exercised heart, which prompted us to investigate the ...
Yihua Bei, Dongchao Lu, C. Bär, Shambhabi Chatterjee, Alessia Costa, I. Riedel, F. Mooren, Yujiao Zhu, Zhenzhen Huang, Meng Wei, Meiyu Hu, Sunyi Liu, Pujiao Yu, Kun Wang, T. Thum, Junjie Xiao   +15 more
semanticscholar   +1 more source

MOF-derived bimetallic nanozyme to catalyze ROS scavenging for protection of myocardial injury

Theranostics, 2023
Rationale: Myocardial injury triggers intense oxidative stress, inflammatory response, and cytokine release, which are essential for myocardial repair and remodeling.
Kaiyan Xiang, Haoguang Wu, Yu Liu, Sheng-Jie Wang, Xue-lin Li, Bowei Yang, Yunming Zhang, Long Ma, Guangming Lu, Liangcan He, Qianqian Ni, Longjiang Zhang   +11 more
semanticscholar   +1 more source

Sevoflurane Postconditioning Attenuates Hypoxia/Reoxygenation Injury of Cardiomyocytes Under High Glucose by Regulating HIF-1α/MIF/AMPK Pathway

Frontiers in Pharmacology, 2021
Subject: Cardiovascular disease, as a very common and serious coexisting disease in diabetic patients, and is one of the risk factors that seriously affect the prognosis and complications of surgical patients. Previous studies have shown that sevoflurane
Haiping Ma, Yongjie Li, Tianliang Hou, Jing Li, Long Yang, Hai Guo, Lili Li, Mingxiu Xin, Zhongcheng Gong   +8 more
doaj   +1 more source