Results 101 to 110 of about 159,601 (304)

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Sex Differences in Timeliness of Reperfusion in Young Patients With ST‐Segment–Elevation Myocardial Infarction by Initial Electrocardiographic Characteristics

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundYoung women with ST‐segment–elevation myocardial infarction experience reperfusion delays more frequently than men. Our aim was to determine the electrocardiographic correlates of delay in reperfusion in young patients with ST‐segment–elevation
Aakriti Gupta, Jose A. Barrabes, Kelly Strait, Hector Bueno, Andreu Porta‐Sánchez, J. Gabriel Acosta‐Vélez, Rosa‐Maria Lidón, Erica Spatz, Mary Geda, Rachel P. Dreyer, Nancy Lorenze, Judith Lichtman, Gail D'Onofrio, Harlan M. Krumholz   +13 more
doaj   +1 more source

Remote ischemic preconditioning in patients with intermittent claudication [PDF]

, 2013
OBJECTIVE: Remote ischemic preconditioning (RIPC) is a phenomenon in which a short period of sub-lethal ischemia in one organ protects against subsequent bouts of ischemia in another organ.
Chehuen, M, Cucato, Gabriel, Farah, BQ, Puech-Leão, P, Ragazzo, L, Ritti-Dias, RM, Rosoky, RM, Saes, GF, Wolosker, N, Zerati, AE   +9 more
core   +5 more sources

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Role of cardiac renin angiotensin system in ischemia reperfusion injury and preconditioning of heart

Indian Heart Journal, 2016
Cardio-vascular diseases are the leading cause of morbidity and mortality. Ischemia is a state of oxygen deprivation in tissues, whereas reperfusion is restoration of blood flow in ischemic tissues.
Vimal Agrawal, Jeetendra Kumar Gupta, Shaiba Sana Qureshi, Vishal Kumar Vishwakarma   +3 more
doaj   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

THE EFFECTIVENESS OF PRECONDITIONING AND POSTCONDITIONING WITH ADENOSINE IN PREVENTION OF REPERFUSION DAMAGE IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION

Архивъ внутренней медицины, 2018
The study aimed to evaluate the effectiveness of pharmacological preconditioning and postconditioning with sublingual adenosine in prevention of reperfusion damage in patients with ST-segment elevation myocardial infarction.Material and methods.
N. T. Vatutin, A. N. Shevelok, V. S. Kolesnikov   +2 more
doaj   +1 more source

Reference invasive tests of microvascular injury in myocardial infarction [PDF]

, 2017
No abstract ...
Berry, Colin, Maznyczka, Annette Marie, McCartney, Peter   +2 more
core   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source