Results 231 to 240 of about 159,601 (304)

Editorial Note: Tilianin attenuates inflammasome activation in endothelial progenitor cells to mitigate myocardial ischemia-reperfusion injury. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

Annals of Neurology, Volume 99, Issue 5, Page 1210-1223, May 2026.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito, P. Calleja, L. Alzamora, A. Ruiz‐García, A. Martínez‐Salio, M. Muñoz‐García, F. Ostos, A. García‐Culebras, A. Moraga, M.A. Moro, I. Lizasoain   +10 more
wiley   +1 more source

Cardiogenic Shock (SCAI Stage D) Following Pharmacological Reperfusion of Anterior ST-Segment Elevation Myocardial Infarction in a Young Woman: A Case Report. [PDF]

Cureus
Torres-Verduzco JI, Balderas-Santoyo JI, Torres-Salazar QL.   +2 more
europepmc   +1 more source

Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders

Advanced NanoBiomed Research, Volume 6, Issue 5, May 2026.
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng, Yu‐Ge Wang, Ya‐Bing Zhang, Yuan‐Xin Bai, Si‐Tong Lin, Ting‐Ting Zhu, Yan‐Bo Zhou, Wei‐Tong Pan, Pan‐Miao Liu, Jian‐Jun Yang   +9 more
wiley   +1 more source

Cardioprotective effects of the ranolazine in myocardial infarction mediated by stimulation of the endogenous mediators involved in ischemic preconditioning. [PDF]

Acta Cir Bras
Tantray J, Menezes-Rodrigues FS, Podanosque JM, Tallo FS, Caricati-Neto A, Sharma AK, Patel A, Sharma RK, Singh S, Beibituly BA.   +9 more
europepmc   +1 more source

MicroRNA‐Mediated Regulation of Brain Aging Hallmarks: Implications for Neurodegeneration and Neural Recovery

Brain and Behavior, Volume 16, Issue 5, May 2026.
Hallmarks of brain aging regulated by microRNAs (miRNAs). This graphical abstract illustrates the central role of miRNAs in coordinating key biological processes associated with brain aging. miRNAs regulate multiple interconnected hallmarks, including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis and impaired ...
Mustafa T. Ardah, Pareshkumar N. Patel, Omayma Salim Waleed, Jamuna K. V., Vandana Tripathi, L. Lakshmi, Rajashree Panigrahi, Manoj Kumar Mishra   +7 more
wiley   +1 more source

Plasma EDA2R and Risk of Cardiovascular Diseases and All‐Cause Mortality: Analysis of the UK Biobank Cohort

Clinical Cardiology, Volume 49, Issue 5, May 2026.
In this large‐scale UK Biobank analysis, elevated plasma EDA2R was associated with a 74% higher risk of cardiovascular disease and a 177% higher risk of all‐cause mortality, with a 7.2‐year loss in life expectancy in the highest EDA2R group, suggesting its potential as a prognostic biomarker and therapeutic target.
Ziqing Ruan, Jiabin Tu, Hongli Xu, Yupeng Zhi, Chun Chen, Kaiyang Lin, Yansong Guo   +6 more
wiley   +1 more source

Cardioprotective effects of puerarin against myocardial ischemia-reperfusion injury: a preclinical systematic review and meta-analysis. [PDF]

Front Pharmacol
Chen D, Xue C, Liang Z, Wang X, Shi Z, Yao M, Wang Y, Jiang L.   +7 more
europepmc   +1 more source

Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
Adenosine, as a key metabolic and neurotransmitter in the brain, has become an important therapeutic target for improving the efficacy of immunotherapy for stroke. However, gaps in knowledge about its metabolic pathways have become a key factor limiting its clinical translation.
Shu Zhu, Shanshan Zhong, Xiaoru Lin, Chuansheng Zhao, Yugang Li   +4 more
wiley   +1 more source

HBO‐PC Reprograms Neuroimmune Metabolism Through Disruption of the LRG1‐HIF‐1α‐IL‐6‐STAT3 Amplification Loop Attenuates Pyroptosis and Ischemia–Reperfusion Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
A mouse CIRI model was generated by middle cerebral artery occlusion. HBO‐PC and LRG1 siRNA knockdown were applied. Neurological function and molecular changes were evaluated. We confirmed that HBO‐PC reprograms neuroimmune metabolism through disruption of the LRG1‐HIF‐1α‐IL‐6‐STAT3 amplification Loop attenuates pyroptosis and ischemia–reperfusion ...
Wenying Lv, Junzhe Lv, Kexin Xiong, Shunshun Yuan, Jingyao Yang, Dazhi Guo   +5 more
wiley   +1 more source