Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao +13 more
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Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury. [PDF]
Houang EM +6 more
europepmc +1 more source
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte +3 more
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Identification of splenic IRF7 as a nanotherapy target for tele-conditioning myocardial reperfusion injury. [PDF]
Long Q +26 more
europepmc +1 more source
Amentoflavone, a preferentially TGF‐ββ receptor 1 inhibitor, attenuates transverse aortic constriction (TAC)‐triggered cardiac hypertrophy, fibrosis, and dysfunction by suppressing downstream Smad and MAPK signaling cascades in cardiomyocytes and cardiac fibroblasts.
Jiangjiao Wu +10 more
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Mitochondrial transplantation combined with mitoquinone and melatonin: A survival strategy against myocardial reperfusion injury in aged rats. [PDF]
Mokhtari B +3 more
europepmc +1 more source
Correction to "Failure to Protect Against Myocardial Ischemia-Reperfusion Injury With Sevoflurane Postcondioning in Old Rats In Vivo". [PDF]
Acta Anaesthesiologica Scandinavica, Volume 70, Issue 3, March 2026.
europepmc +2 more sources
Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley +1 more source
A novel intracoronary hypothermia device reduces myocardial reperfusion injury in pigs. [PDF]
Pei Z +14 more
europepmc +1 more source
Apigenin Alleviates Myocardial Reperfusion Injury in Rats by Downregulating miR-15b. [PDF]
Wang P, Sun J, Lv S, Xie T, Wang X.
europepmc +1 more source

